Multifaceted Cooperation Between WNT and PI3K Signaling Axis through the Long Noncoding RNA SNHG16 and TCF7 in de novo Acute Lymphoblastic Leukemia Patients [0.03%]
长链非编码RNA SNHG16通过WNT和PI3K信号轴中的TCF7在初发急性淋巴细胞白血病患者中发挥多面作用
Mohadeseh Khani,Atbin Latifi,Mohammad Sayyadi
Mohadeseh Khani
Background: Acute lymphoblastic leukemia is the most prevalent form of acute leukemia in children, arising from the known and unknown factors. This complexity has limited advancements in patient recovery. Recently, lncRNA...
Atorvastatin-Infused Carboxymethyl Cellulose-Gelatin Hydrogel: A Synergistic Strategy for Enhanced Wound Healing and Skin Tissue Regeneration [0.03%]
阿托伐他汀浸膏羧甲基纤维素-明胶水凝胶：一种增强伤口愈合和皮肤组织再生的协同策略
Seyed Reza Mousavi,Mojtaba Rashidi,Azam Khedri et al.
Seyed Reza Mousavi et al.
Background: Skin tissue engineering is an innovative alternative to traditional methods for addressing skin injuries. The aim of this study is to synthesize a hydrogel consisting of carboxymethyl cellulose (CMC) and gelat...
Development of Experimental Platforms to Assess Helicobacter pylori HopQ Interaction with Host CEACAM Molecules [0.03%]
Hp菌HopQ与宿主CEACAM分子相互作用的实验平台建立
Nazanin Shans,Maryam Esmaeili,Kimia Abraheh et al.
Nazanin Shans et al.
Background: Helicobacter pylori is an extracellular bacterium responsible for various gastrointestinal diseases, such as peptic ulcers and gastric cancer. It uses multiple mechanisms to colonize the harsh, acidic environm...
Effects of Peptides and Bioactive Peptides on Acute Kidney Injury: A Review Study [0.03%]
肽和生物活性肽对急性肾损伤影响的研究进展综述
Zeynab Mohamadi Yarijani,Houshang Najafi
Zeynab Mohamadi Yarijani
Acute kidney injury is the sudden loss of kidney function that occurs within hours or days, resulting in the accumulation of waste materials in the blood and disruption of fluid balance. AKI is prevalent among hospitalized patients, especia...
Migration Pattern and Tissue Tropism of Toxascaris leonina (Linstow, 1902) Larvae: An in vivo Evaluation [0.03%]
托新虫（Toxascaris leonina）幼虫的移行模式及其组织嗜性：体内评价
Mohammad Sardari,Alireza Nourian,Farzad Parsa et al.
Mohammad Sardari et al.
Background: The role of Toxascaris leonina in visceral larva migrans is controversial. This study aimed to investigate the migratory behavior of T. leonina larvae across different organs in mice. ...
Upregulation of CircCSPP1, CircNRIP1, and CircSAMD2 in Breast Cancer and Their Potential as Diagnostic Biomarkers [0.03%]
circCSPP1、circNRIP1和circSAMD2在乳腺癌中的上调及其作为诊断生物标志物的潜力
Mahsa Keshavarz-Fathi,Farzaneh Darbeheshti,Rangarirai Makuku et al.
Mahsa Keshavarz-Fathi et al.
Background: Identifying novel diagnostic biomarkers with stable structures, such as circRNAs can improve the early detection and management of BC. Herein, we conducted this study to analyze the expression profile of four circRNAs, including...
Engineering of the Caspase-3 Gene in Recombinant CHO Cells Caused More Apoptosis Resistance and enhanced Recombinant Protein Production Than the BAX Gene [0.03%]
工程化重组CHO细胞中的Caspase-3基因比BAX基因导致更多的抗凋亡和增强型重组蛋白生成
Amirabbas Rahimi,Morteza Karimipoor,Reza Mahdian et al.
Amirabbas Rahimi et al.
Background: BAX and caspase-3 are essential genes in the apoptotic pathway of cells, promoting the apoptotic cascade through different mechanisms. Inhibition of these genes can increase the longevity of cells in cell cult...
Antifungal Potential of Streptomyces-Derived Metabolites Against Fluconazole-Resistant Oral Candida albicans: In vitro Evaluation and Mechanistic Insights [0.03%]
链霉菌衍生代谢物抗口腔念珠菌的抗真菌潜力：体外评价及机制研究
Mahtab Karami-Feli,Zahra Jahanshiri,Akram Sadeghi
Mahtab Karami-Feli
Background: Oropharyngeal candidiasis, primarily caused by C. albicans, is the most common opportunistic fungal infection in patients with head and neck cancer. The increasing emergence of FLZ resistance has led to higher...
Role of hsa_Circ_0001821 in Colorectal Cancer Pathogenesis and Response to 5-Fluorouracil through miR-203a-3p/FGF-2 Axis [0.03%]
hsa_circ_0001821通过miR-203a-3p/FGF-2轴在结直肠癌发病机制和氟尿嘧啶反应中的作用
Pejman Molaei,Ali Mahdavinezhad,Rezvan Najafi et al.
Pejman Molaei et al.
Background: Chemoresistance, the primary cause of disease relapse and treatment failure, poses a significant challenge in the treatment of CRC. Understanding the molecular mechanisms that underlie the pathogenesis and che...
Unraveling Leishmania major Metacyclogenesis: A Comprehensive Analysis of Transcriptomic and Metabolomic Profiles [0.03%]
解缠盘利什曼原虫成熟过程：转录组和代谢组分析
Mansour Aminzadeh,Fariborz Bahrami,Zeynab Piryaei et al.
Mansour Aminzadeh et al.
Background: Metacyclogenesis is a critical developmental process in the life cycle of Leishmania parasites, particularly in their transition from non-infective procyclic to infective metacyclic promastigotes. This transfo...