Extracting Potential New Targets for Treatment of Adenoid Cystic Carcinoma using Bioinformatic Methods [0.03%]
利用生物信息学方法寻找涎腺腺样囊性癌潜在治疗新靶点
Tayebeh Forooghi Pordanjani,Bahareh Dabirmanesh,Peyman Choopanian et al.
Tayebeh Forooghi Pordanjani et al.
Background: Adenoid cystic carcinoma is a slow-growing malignancy that most often occurs in the salivary glands. Currently, no FDA-approved therapeutic target or diagnostic biomarker has been identified for this cancer. T...
Formulation and Characterization of a Novel Oxidized Alginate-Gelatin-Silk Fibroin Bioink with the Aim of Skin Regeneration [0.03%]
一种用于皮肤再生的新型氧化海藻酸-明胶-家蚕丝蛋白生物墨水的制备及表征
Khadijeh Sanaei,Ali Zamanian,Shohreh Mashayekhan et al.
Khadijeh Sanaei et al.
Background: In the present study, a novel bioink was suggested based on the oxidized alginate (OAlg), gelatin (GL), and silk fibroin (SF) hydrogels. Metho...
Development of Stable CHO-K1 Cell Lines Overexpressing Full-Length Human CD20 Antigen [0.03%]
人全长CD20抗原高效表达中国仓鼠卵巢细胞系的构建及筛选
Niloufar Mohammadkhani,Azam Rahimpour,Reyhaneh Hoseinpoor et al.
Niloufar Mohammadkhani et al.
Background: CD20 is a differentiation-related antigen exclusively expressed on the membrane of B lymphocytes. CD20 amplification is observed in numerous immune-related disorders, making it an ideal target for immunotherap...
Antimicrobial Effects of Mouse Adipose-Derived Mesenchymal Stem Cells Encapsulated in Collagen-Fibrin Hydrogel Scaffolds on Bacteroides fragilis Wound Infection in vivo [0.03%]
包裹脂肪源性间充质干细胞的胶原-纤粘蛋白水凝胶支架对小鼠伤口感染脆弱拟杆菌的抗菌作用研究
Mansoor Khaledi,Mohammad Hossein Ahmadi,Parviz Owlia et al.
Mansoor Khaledi et al.
Background: Anaerobes are the causative agents of many wound infections. B. fragilis is the most prevalent endogenous anaerobic bacterium causes a wide range of diseases, including wound infections. This study aimed to as...
Human Umbilical Cord Mesenchymal Stem Cell-Derived Microvesicles Could Induce Apoptosis and Autophagy in Acute Myeloid Leukemia [0.03%]
人源脐带间充质干细胞衍生微泡可通过诱导凋亡及自噬杀伤急性髓系白血病细胞
Mohammad Khani-Eshratabadi,Seyed Hadi Mousavi,Morteza Zarrabi et al.
Mohammad Khani-Eshratabadi et al.
Background: Microvesicles (MV) have been identified as candidate biomarkers for treating acute myeloid leukemia (AML). This study investigated the effects of human umbilical cord-derived mesenchymal stem cell (hUCMSC)-der...
CRISPR-Cas Technology as a Revolutionary Genome Editing tool: Mechanisms and Biomedical Applications [0.03%]
CRISPR-Cas技术作为革命性的基因编辑工具：机制及生物医药应用
S Ebrahimi,Mohammad Ali Khosravi,Abbasali Raz et al.
S Ebrahimi et al.
Programmable nucleases are powerful genomic tools for precise genome editing. These tools precisely recognize, remove, or change DNA at a defined site, thereby, stimulating cellular DNA repair pathways that can cause mutations or accurate r...
Evaluation of mRNA Expression of CD244 and Its Adapter Molecules in CD8+ T Cells in Acute Leukemia [0.03%]
急性白血病CD8+t细胞中CD244及其衔接分子的表达检测
Maryam Mohammadi,Hossein Asgarian-Omran,Ahmad Najafi et al.
Maryam Mohammadi et al.
Background: This study investigated the role of the immune-checkpoint receptor (ICR), CD244, and its adapter molecules, in CD8+ T cells in acute leukemia. ...
Isorhamnetin Exerts Antifibrotic Effects by Attenuating Platelet-Derived Growth Factor-BB-induced HSC-T6 Cells Activation via Suppressing PI3K-AKT Signaling Pathway [0.03%]
山柰酚通过抑制PI3K-Akt信号通路减轻血小板源性生长因子诱导的HSC-T6细胞活化及肝纤维化的研究
Mojtaba Rashidi,Emad Matour,Hasti Beheshti Nasab et al.
Mojtaba Rashidi et al.
Background: Currently, liver fibrosis is growing worldwide; unfortunately, there is no definite cure for this disease. Hence, understanding the molecular pathways involved in the development of liver fibrosis can help to ...
Identification, Characterization, and Modeling of a Bioinsecticide Protein Isolated from Scorpion Venom gland: A Three-Finger Protein [0.03%]
来源于蝎毒腺生物杀虫剂蛋白的鉴定、表征及建模：一个三指蛋白
Masoumeh Baradaran,Masoud Mahdavinia,Maryam Naderi Soorki et al.
Masoumeh Baradaran et al.
Background: The majority of insecticides target sodium channels. The increasing emergence of resistance to the current insecticides has persuaded researchers to search for alternative compounds. Scorpion venom gland as a ...
Anticancer Effect of Enterococcus faecium, Isolated from Vaginal Fluid, on Ovarian Cancer Cells [0.03%]
从阴道液中分离的肠球菌FM-01及其提取物对卵巢癌细胞的抗癌作用研究
Soraya Pourmollaei,Azizeh Farshbaf-Khalili,Abolfazl Barzegari et al.
Soraya Pourmollaei et al.
Background: Given the association between cervicovaginal microbiota and OVC, we investigated the effect of Enterococcus faecium conditioned medium (CM) on OVC (Caov-4) cells. ...