Identification of Renal Transplantation Rejection Biomarkers in Blood Using the Systems Biology Approach [0.03%]
使用系统生物学方法识别血液中的肾移植排斥生物标志物
Fatemeh Saberi,Zeinab Dehghan,Effat Noori et al.
Fatemeh Saberi et al.
Background: Renal transplantation plays an essential role in the quality of life of patients with end-stage renal disease. At least 12% of the renal patients receiving transplantations show graft rejection. One of the met...
Lessons from COVID-19 Pandemic: A Successful Policy and Practice by Pasteur Institute of Iran [0.03%]
新冠大流行带来的启示：伊朗巴斯德研究所的成功政策和实践
Mona Sadat Larijani,Alireza Biglari,Rahim Sorouri et al.
Mona Sadat Larijani et al.
The present study aims to provide an insight to the comprehensive efforts of Pasteur Institute of Iran (PII) regarding COVID-19 management, research, achievements, and vaccine production, though there are many challenges. The relevant liter...
The Role of High-Fructose Diet in Liver Function of Rodent Models: A Systematic Review of Molecular Analysis [0.03%]
高果糖饮食在啮齿动物模型肝功能中的作用：分子分析的系统回顾
Roya Mirzaei,Roya Khosrokhavar,Sepideh Arbabi Bidgoli
Roya Mirzaei
The present systematic review of animal studies on long-term fructose intake in rodents revealed a significant decrease in the activities of antioxidant enzymes due to a fructose-rich diet. The reduced activity of these enzymes led to an in...
Identification of Novel Mutations in the MMAA and MUT Genes among Methylmalonic Aciduria Families [0.03%]
MMAA和MUT基因中甲基马尿酸血症家系中新型突变的识别
Mahboobeh Jafari,Fatemeh Karami,Aria Setoodeh et al.
Mahboobeh Jafari et al.
Background: Methylmalonic aciduria is a rare inherited metabolic disorder with autosomal recessive inheritance pattern. There are still MMA patients without known mutations in the responsible genes. This study aimed to id...
Decoding the Genetic and Structural Features of HPV16 E5 Oncogene in Cervical Cancer Isolates from Pakistan: A Pilot Study [0.03%]
对巴基斯坦宫颈癌分离株中HPV16 E5癌基因的遗传和结构特征进行了解码：初步研究
Naureen Ehsan Ilahi,Nayyer Siddique,Muhammad Ibrahim Rashid et al.
Naureen Ehsan Ilahi et al.
Background: Many anogenital cancers are caused by high-risk HPV. The most common subtype is HPV16, which is prevalent in the world, including Pakistan. Various amino acid residues in HPV16 E5 are associated with high cell...
Osteoproductivity in Experimentally Induced Cranial Bone Defects in Rabbits [0.03%]
兔实验性颅骨缺损的骨生成能力研究
Alkın Ünsal,Ercan Durmuş,İlhami Çelik
Alkın Ünsal
Background: Autogenous bone grafts are the gold standard for being used as graft materials in maxillofacial surgery. However, a limited amount of these materials is available from the donor site, and there is also more ne...
Increased Expression of NOTCH-1 and T Helper Cell Transcription Factors in Patients with Acquired Aplastic Anemia [0.03%]
获得性再生障碍性贫血患者NOTCH-1信号转导途径及T淋巴细胞活化的研究
Vandana Sharma,Manju Namdeo,Prabin Kumar et al.
Vandana Sharma et al.
Background: Acquired aplastic anemia is an autoimmune disease in which auto-aggressive T cells destroy hematopoietic progenitors. T-cell differentiation is controlled by transcription factors that interact with NOTCH-1, w...
Nona-Arginine Mediated Anti-E6 ShRNA Delivery Suppresses the Growth of Hela Cells in vitro [0.03%]
由瓜尔豆胶衍生的非精氨酸低聚肽介导的抗E6 shRNA传递抑制体外HeLa细胞增殖
Razieh Taghizadeh Pirposhteh,Ehsan Arefian,Arash Arashkia et al.
Razieh Taghizadeh Pirposhteh et al.
Background: The E6 oncoprotein of HPV plays a crucial role in promoting cell proliferation and inhibiting apoptosis, leading to tumor growth. Non-viral vectors such as nona-arginine (R9) peptides have shown to be potentia...
Evaluation of Vascular Endothelial Growth Factor Gene Expression in Recellularized Liver Tissue by Mouse Embryo Fibroblast [0.03%]
利用小鼠胚胎成纤维细胞评价再细胞化肝组织中血管内皮生长因子基因表达
Motahare Homayoon Vala,Hamed Bagheri,Sargazi Zinat et al.
Motahare Homayoon Vala et al.
Background: The aim of the present study was to evaluate alterations in the vegf gene expression as an angiogenic factor in mouse embryo fibroblasts seeded on the decellularized liver fragments. ...
In silico Analysis of Two Novel Variants in the Pyruvate Carboxylase (PC) Gene Associated with the Severe Form of PC Deficiency [0.03%]
与丙酮酸羧化酶缺乏症严重型相关的两个新型变异的计算机分析研究
Fereshteh Maryami,Elham Rismani,Elham Davoudi-Dehaghani et al.
Fereshteh Maryami et al.
Background: Inborne errors of metabolism are a common cause of neonatal death. This study evaluated the acute early-onset metabolic derangement and death in two unrelated neonates. ...