Intrathecal injections of non-peptide oxytocin receptor agonists, WAY 267,464 and TC OT 39, induce significant anti-hyperalgesia in both male and female rats with inflammatory pain [0.03%]
非肽催产素受体激动剂WAY 267,464和TC OT 39脊髓内注射对炎性痛大鼠产生明显的抗高敏作用
Lok-Hi Chow,Yuan-Hao Chen,Ying-Jie Chen et al.
Lok-Hi Chow et al.
Objectives: Hyperalgesia is a clinical condition related to chronic pain in which patients experience increased nociceptive sensitivity. Intrathecal oxytocin has been shown to induce significant anti-hyperalgesia in both ...
Sustained neutrophil infiltration and bacterial grain morphology underlie chronic mycetoma pathology in a murine model [0.03%]
小鼠模型中持续的中性粒细胞浸润和真菌颗粒形态决定了慢性霉菌瘤的病理变化
Maria L Ruiz-de la Cruz,Anna V Vazquez-Marmolejo,Manuel G Mejia-Torres et al.
Maria L Ruiz-de la Cruz et al.
Objectives: This study aimed to characterize the progression of chronic mycetoma caused by Nocardia brasiliensis in a BALB/c murine model, focusing on the interplay between host cellular immune responses, bacterial burden...
Chrysin promotes oral ulcer healing via modulating matrix metalloproteinases and vascular endothelial growth factor in rats [0.03%]
染料木素通过调节大鼠口腔溃疡中基质金属蛋白酶和血管内皮生长因子的表达促进口腔溃疡的愈合
Abeer Salama,Rania Elgohary
Abeer Salama
Objectives: Oral ulcers are a common inflammatory condition affecting the mucosal lining, often causing pain and discomfort. Chrysin is a natural flavonoid with well-documented anti-oxidant and anti-inflammatory propertie...
Estrogen and progesterone attenuate CD4-positive immune cell traffic to the penumbra region of rat's ischemic stroke brain [0.03%]
雌激素和黄体酮通过减少CD4免疫细胞迁移到缺血性卒中脑半暗带区域发挥神经保护作用
Abutaleb Tamtaji,Sayyed Alireza Talaei,Homayoun Naderian et al.
Abutaleb Tamtaji et al.
Objectives: Stroke is an acute cerebrovascular disease with a high incidence, high disability rate, and high mortality. Stroke damages the integrity of the blood-brain barrier. Immune cells are concerned with multiple fac...
Heat shock protein 90 mediates the protective effects of vericiguat on myocardial ischemia/reperfusion injury by inhibiting toll-like receptor 4 and c-Jun N-terminal kinases [0.03%]
热休克蛋白90介导维立西呱通过抑制 Toll 样受体 4 和 c-Jun 氨基末端激酶对抗心肌缺血/再灌注损伤的保护作用
Si-Jie Pan,Jun-Yan Chen,Dong-Xiao Wang et al.
Si-Jie Pan et al.
Objectives: This study aimed to investigate whether vericiguat exerts a protective effect against myocardial ischemia-reperfusion injury (MIRI) by inhibiting toll-like receptor 4 (TLR4) and c-Jun N-terminal kinases (JNK) ...
Spermine: A prospective treatment for high glucose-induced myocardial fibrosis in db/db mice [0.03%]
spermidine：有望成为治疗db/db小鼠高糖诱导的心肌纤维化的方法
Yong Liu,Xinyu Liu,Shuang Li et al.
Yong Liu et al.
Objectives: This study explored the molecular mechanism by which exogenous spermine attenuates diabetic cardiomyopathy (DCM)-induced myocardial fibrosis. ...
Corrigendum: Anticancer activity of Pseudomonas aeruginosa derived peptide with iRGD in colon cancer therapy [0.03%]
简报：铜绿假单胞菌衍生的含iRGD肽在结肠癌治疗中的抗肿瘤活性校正原文发表日期：2019年8月1日
[This corrects the article DOI: 10.22038/IJBMS.2023.68331.14913.].
Published Erratum
Iranian journal of basic medical sciences. 2025;28(7):962. DOI:10.22038/ijbms.2025.25959 2025
Thymoquinone prevents valproic acid-induced hepatotoxicity via modulation of cytochrome P450, PPARs, and apoptotic pathways [0.03%]
胡椒酚通过调节细胞色素P450、PPAR及其凋亡途径预防丙戊酸诱导的肝毒性
Sebile Azırak,Sedat Bilgiç,Deniz Taştemir Korkmaz et al.
Sebile Azırak et al.
Objectives: Thymoquinone (TQ) is the main bioactive component of Nigella sativa L. and has anti-oxidant, anti-hepatotoxic, anti-cancer, anti-hypertensive, hypoglycemic, anti-inflammatory, and lipid-lowering properties. In...
Maximizing the therapeutic benefits of biopolymer-derived nanoparticles in wound healing [0.03%]
最大化生物聚合物衍生纳米颗粒在伤口愈合中的治疗益处
Seyedeh Farnaz Darghiasi,Fatemeh Rajabi,Ashkan Farazin
Seyedeh Farnaz Darghiasi
Nanoparticles have emerged as a cornerstone of nanomedicine, offering transformative potential to modern healthcare through their multifunctional capabilities. Their adaptability positions them as ideal candidates for wound management, eith...
Substrate engineering using naturally biomimicking corneal cell topography for preserving stemness of corneal limbal epithelial-stem cells [0.03%]
利用仿生角膜细胞拓扑结构的基底工程来保持角膜缘上皮干细胞的干性
Tahereh Manoochehrabadi,Ali Samadikuchaksaraei,Amin Solouki et al.
Tahereh Manoochehrabadi et al.
Objectives: Substrate engineering is one of the attractive fields of changing cell behavior and fate, especially for stem cell (SC) therapies. The SC pool is an essential factor in transplantation outcomes. Here, the obje...