Synergistic effect of carbomer polymer and graphene oxide nanoparticles on the rat wound healing process [0.03%]
卡波姆聚合物和氧化石墨烯纳米粒子对大鼠伤口愈合过程的协同作用
Yousef Moradian,Tahereh Sadat Tabatabai,Tayebeh Sadat Tabatabai et al.
Yousef Moradian et al.
Objectives: Wound healing is a multifaceted process involving inflammation, proliferation, and remodeling phases. Effective wound management requires materials that can promote tissue regeneration while preventing infecti...
Protective role of astaxanthin against bisphenol A induced biochemical and histopathological alterations in rat kidneys [0.03%]
虾青素对双酚A致大鼠肾脏生化和组织病理损伤的保护作用研究
Burcu Gültekin,Seda Çetinkaya Karabekir,İlknur Çınar Ayan et al.
Burcu Gültekin et al.
Objectives: This study investigates the ability of astaxanthin (ASTX), a powerful anti-oxidant, to protect kidney tissue from oxidative and cellular damage resulting from bisphenol A (BPA) toxicity, a widespread global to...
Advances in cancer immunotherapy: Strategies and innovations strategies for adoptive immunotherapy of cancer [0.03%]
癌症免疫治疗进展：肿瘤适应性免疫治疗策略及创新疗法
Leila Moeinzadeh,Mohammad-Reza Mahmoudian-Sani,Daryush Purrahman et al.
Leila Moeinzadeh et al.
Cancer immunotherapy has emerged as a transformative approach in oncology, offering alternatives beyond traditional treatments. This narrative review focuses on major innovations, including adoptive cell therapy (ACT), chimeric antigen rece...
Comparing transplantation sites of mouse immature testicular tissue fragments embedded in chitosan scaffold to maintain tissue integrity: Epididymal fat pad or under the back skin [0.03%]
比较透明质封装的小鼠不成熟睾丸组织片移植部位：附睾脂肪垫或背部皮肤下
Alireza Anvari,Mansoureh Movahedin,Fariba Ganji
Alireza Anvari
Objectives: Cryopreservation of immature testicular tissue (ITT) is currently the only technique available for restoring fertility in adolescent boys with cancer. Preclinical investigations assessing the development of hu...
Toxicological evaluation and preliminary phytochemical characterisation of a Nigerian Cannabis sativa chemovar [0.03%]
尼日利亚大麻化学变种的毒理学评估和初步植物化学特征分析
Ebele Joan Ajagun,Babatunde Adebola Alabi,Abdul-Musawwir Alli-Oluwafuyi et al.
Ebele Joan Ajagun et al.
Objectives: Different Cannabis sativa chemovars produce diverse pharmacological and behavioral effects. With the widespread use of cannabis in Nigeria, detailed toxicological effects of Nigerian chemovars are lacking. Thi...
Innovative strategies and nanocarrier approaches for enhancing the oral bioavailability of macromolecular therapeutics [0.03%]
用于提高大分子治疗药物口服生物利用度的创新策略和纳米递送系统方法学研究进展
Pallavi Guduganahalli Manjunath,Nithin Kikkeri Ravi,Srikruthi Kunigal Sridhar et al.
Pallavi Guduganahalli Manjunath et al.
This review focuses on identifying the primary limitations affecting the oral administration of biologics and evaluates current strategies designed to improve their bioavailability. It also incorporates a bibliometric mapping approach to as...
Examining the role of trans-sodium crocetinate in alleviating colistin-induced cytotoxicity through apoptosis and autophagy pathways on HEK-293 cells [0.03%]
探讨trans-钠金丝桃素通过凋亡和自噬途径缓解多粘菌素致HEK-293细胞毒性的机制研究
Karim Naraki,Mahboobeh Ghasemzadeh Rahbardar,Bibi Marjan Razavi et al.
Karim Naraki et al.
Objectives: Colistin is a crucial antibiotic for multidrug-resistant Gram-negative bacterial infections, but its nephrotoxicity limits clinical use. Trans sodium crocetinate (TSC), a synthetic crocetin derivative, exhibit...
Preclinical efficacy assessment of umbilical cord mesenchymal stem cell therapy for acute liver failure [0.03%]
评估胎盘间充质干细胞治疗急性肝衰竭的药效学作用力
Danpeng Shen,Fan Xie,Weikang Chen et al.
Danpeng Shen et al.
Objectives: Acute liver failure (ALF) is a life-threatening condition marked by rapid hepatocellular damage. This study investigates the therapeutic efficacy of human umbilical cord-derived mesenchymal stem cells (hUCMSCs...
Acute exposure to 27.12 MHz radiofrequency electromagnetic field disrupts blood-brain barrier integrity via eNOS activation and occludin down-regulation [0.03%]
27.12兆赫射频电磁场急性暴露通过激活内皮型一氧化氮合酶和闭锁蛋白下调破坏血脑屏障完整性
Arzu Ulusoy,Halil Asci,Rumeysa Taner et al.
Arzu Ulusoy et al.
Objectives: Controlled modulation of blood-brain barrier (BBB) permeability without inducing damage represents a promising strategy for enhancing central nervous system drug delivery. ...
Effects of chitosan-titanium dioxide-Glucantime nanoassemblies on Leishmania major: An in vitro and in vivo study [0.03%]
壳聚糖-二氧化钛-Glucantime纳米组装对利什曼原虫的作用：体外和体内研究
Sanaz Tavakoli,Jaleh Varshosaz,Sedigheh Saberi et al.
Sanaz Tavakoli et al.
Objectives: Leishmaniasis, a neglected tropical disease, remains a public health concern. Meglumine antimonate (Glucantime®) is associated with high toxicity, prolonged treatment duration, and the emergence of drug resis...