Microbiological acceptance criteria, specifications of herbal drugs and herbal drug preparations in various pharmacopoeias: a global scenario [0.03%]
药典中草药及中草药制剂的微生物可接受标准及规格：全球概况
Ramesh Munukuntla,Akhilesh Tiwari,Ravi Shankar Yadav et al.
Ramesh Munukuntla et al.
Purpose: A pharmacopoeia is a compendium of guidelines and criteria for drug quality. It was established by a national or regional entity and has legal significance. This applies to administration of drugs in a particular...
Developing an AI-based prediction model for anaphylactic shock from injection drugs using Japanese real-world data and chemical structure-based analysis [0.03%]
基于日本真实世界数据和化学结构分析的注射药物过敏性休克的AI预测模型开发
Tomoyuki Enokiya,Kaito Ozaki
Tomoyuki Enokiya
Background: This study aims to develop an AI-based prediction model for injection drugs that cause anaphylactic shock using Japanese Real-World Data (JADER database) and chemical structure-based analysis. ...
New amide and diterpene alkaloids with anticholinesterase activity from Delphinium cyphoplectrum roots [0.03%]
具有抗乙酰胆碱酯酶活性的毛茛属植物藏边银莲花根中的amide和二萜类生物碱成分
Arash Salehi,Behzad Zolfaghari,Mahmoud Aghaei et al.
Arash Salehi et al.
Background: The cholinergic hypothesis posits a robust correlation between the onset of Alzheimer's disease and a pronounced deficit in acetylcholine, a pivotal neurotransmitter crucial for the central cholinergic nervous...
Educational interventions in pharmacovigilance to improve the knowledge, attitude and the report of adverse drug reactions in healthcare professionals: Systematic Review and Meta-analysis [0.03%]
药品警戒中的教育干预措施以提高医疗卫生专业人员对不良药物反应的认识，态度和报告：系统评价和荟萃分析
Mónica J Cervantes-Arellano,Osvaldo D Castelán-Martínez,Yolanda Marín-Campos et al.
Mónica J Cervantes-Arellano et al.
Objectives: Underreporting of adverse drug reactions (ADRs) limits and delays the detection of signs. The aim of this systematic review with meta-analyses was to synthesize the evidence of educational interventions (EIs) ...
Freeze-drying of bupivacaine lipospheres: preparation, characterization, and evaluation of anti-microbial properties [0.03%]
布比卡因脂质微粒的冻干：制备、特征以及抗菌性能评估
Sepehr Labanian,Homa Faghihi,Hamed Montazeri et al.
Sepehr Labanian et al.
Purpose: To prepare freeze-dried bupivacaine lipospheres intended for topical application in burn injuries. The aim was improving the storage stability and developing a prolonged release pattern to tackle the adverse reac...
Dexmedetomidine alleviates Hypoxia/reoxygenation-induced mitochondrial dysfunction in cardiomyocytes via activation of Sirt3/Prdx3 pathway [0.03%]
右美托咪定通过激活Sirt3/Prdx3途径减轻心肌细胞缺氧/复氧诱导的线粒体功能障碍
Qingyun Tan,Wenming Dong,Qingdong Wang et al.
Qingyun Tan et al.
Background: Myocardial ischemia/reperfusion injury (MIRI) seriously threatens the health of people. The mitochondrial dysfunction in cardiomyocytes can promote the progression of MIRI. Dexmedetomidine (Dex) could alleviat...
Activity of zinc oxide and zinc borate nanoparticles against resistant bacteria in an experimental lung cancer model [0.03%]
锌氧纳米粒子和硼酸锌纳米粒子在实验性肺癌模型中对耐药菌的活性研究
Demet Celebi,Ozgur Celebi,Ali Taghizadehghalehjoughi et al.
Demet Celebi et al.
Background: Recent research indicates a prevalence of typical lung infections, such as pneumonia, in lung cancer patients. Klebsiella pneumoniae, Pseudomonas aeruginosa, and Acinetobacter baumannii stand out as antibiotic...
Antimicrobial activity and mechanism of anti-MRSA of phloroglucinol derivatives [0.03%]
取代三溴酚抗MRSA活性及机制研究
Xianjing Yang,Xinjiao Gao,Jiayi Ou et al.
Xianjing Yang et al.
Background: In previous studies, authors have completed the total synthesis of several phloroglucinol natural products and synthesized a series of their derivatives, which were tested with good biological activities. ...
Oral regimen for high dose methotrexate urine alkalinization: a systematic review and meta-analysis [0.03%]
大剂量甲氨蝶呤尿碱化口服方案：系统回顾与荟萃分析
Romina Kaveh-Ahangaran,Mohammad Abdollahi,Mohammad Vaezi et al.
Romina Kaveh-Ahangaran et al.
Objective: Urine alkalinization prevents nephrotoxicity in patients receiving high-dose methotrexate (HDMTX). While the standard approach involves IV sodium bicarbonate, alternative oral bicarbonate regimens are crucial i...
A critical overview of challenging roles of medicinal plants in improvement of wound healing technology [0.03%]
药用植物在伤口愈合技术改进中的挑战性作用的批判性概述
Deepika Pathak,Avijit Mazumder
Deepika Pathak
Purpose: Chronic diseases often hinder the natural healing process, making wound infections a prevalent clinical concern. In severe cases, complications can arise, potentially leading to fatal outcomes. While allopathic t...