Clinical, humanistic, and economic outcomes of Passiflora alata Curtis use in participants with mild to moderate anxiety: a non-randomized experimental study [0.03%]
柯里辛香藤治疗轻中度焦虑的临床、人文和经济效益：一项实验性研究
Thatiane Bárbara de Barros,Astrid Wiens,Tiago Marques Dos Reis
Thatiane Bárbara de Barros
Background: Anxiety is a disorder treated through psychotherapy and/or pharmacotherapy. Passiflora alata Curtis is a herbal medicine used as a therapeutic alternative, although clinical evidence supporting its effectivene...
Plant-derived compounds as potential candidates for atrial fibrillation drug discovery: A review on phytochemicals with atrial-selective activity [0.03%]
植物源化合物作为心房颤动药物发现的潜在候选物：具有心房选择性活性的植物化学物质综述
Bayan Azizi,Danesh Soltani,Arian Tavasol et al.
Bayan Azizi et al.
Evaluation of metformin's effect on 5-fluorouracil-induced cardiotoxicity through cellular protection [0.03%]
评估二甲双胍对5-氟尿嘧啶致心肌毒性的细胞保护效应
Nahlah Fahad Alreshidi,Reham Abdullah Al-Dhelaan,Amjad Yousuf et al.
Nahlah Fahad Alreshidi et al.
Background: 5-Fluorouracil (5-FU) is a chemotherapeutic agent used primarily to treat various cancers. While it has been successful in improving cancer survival rates, 5-FU is also known to be cardiotoxic. Treatment optio...
The effect of physical activity on epileptic seizures and consequentlearning and memory impairment in electrical amygdala kindling model [0.03%]
运动对电惊厥诱导的大鼠海马痫性发作及学习记忆障碍的影响
Abbas Kebriaeezadeh,Reza Zaferi,Mohammad Sharifzadeh et al.
Abbas Kebriaeezadeh et al.
Background: A recent body of evidence has suggested regular exercise as a promising complementary therapeutic strategy in the management of epilepsy and its related cognitive impairments. ...
Falcarindiol induces apoptosis, ROS accumulation, and cell cycle arrest via EGFR/mTOR pathway modulation: an integrated in silico and in vitro study in cervical cancer [0.03%]
法卡令醇通过调节EGFR/mTOR途径诱导宫颈癌细胞凋亡、ROS积累和细胞周期停滞：一种集成的体内体外研究
Ganesh Timalsina,Bishnu Prasad Parida,Megha Radhakrishnan et al.
Ganesh Timalsina et al.
Background: Falcarindiol, a bioactive polyacetylene, has shown cytotoxic effects in several cancers including breast, colorectal, and oral squamous carcinoma, but its pharmacological actions in cervical cancer are not wel...
Unveiling the multitarget anticancer potential of Cochlospermum religiosum: phytochemical profiling, molecular docking, and in vitro/in vivo validation [0.03%]
Cochlospermum religiosum的多靶抗肿瘤潜力：植物化学分析、分子对接及体内外验证
SaiPrasanna Rasamalla,Jayhind Bharti,Priyadharshini Gogu et al.
SaiPrasanna Rasamalla et al.
Background: Cochlospermum religiosum (CR) is a traditionally valued medicinal plant, but its anticancer constituents and mechanisms remain poorly understood. ...
Comparative efficacy of obicetrapib and anacetrapib in reducing low-density lipoprotein (LDL) levels: a network meta-analysis of clinical trials [0.03%]
obicetrapib与anacetrapib降低低密度脂蛋白(LDL)水平疗效的网络Meta分析研究
Abdel Rahman Jaber,Jihad Abu Zayed,Zaid Alabed et al.
Abdel Rahman Jaber et al.
Background: Cholesteryl ester transfer protein (CETP) inhibitors, specifically anacetrapib and obicetrapib, have shown strong lipid-modifying effects by lowering low-density lipoprotein cholesterol (LDL-C) and altering ot...
Development and evaluation of chitosan-xanthan gum-based controlled release nanoparticles of mebeverine hydrochloride for targeted IBS therapy: in silico, in vitro, and in vivo investigations [0.03%]
基于壳聚糖-黄原胶的羟氯曲美布丁缓释纳米颗粒的开发及评价：针对IBS治疗的模拟、体外和体内研究
V V Siva Krishna Pushadapu,Grandhi Srikar
V V Siva Krishna Pushadapu
Background: Irritable bowel syndrome (IBS) requires long-term, site-specific therapy. Mebeverine hydrochloride is effective but limited by rapid metabolism and frequent dosing. This study aimed to develop colon-targeted, ...
Resveratrol and caffeic acid attenuate diet-induced obesity by inhibiting the SREBP-1/ACLY lipogenic axis in adipose tissue of rats [0.03%]
白藜芦醇和咖啡酸通过抑制SREBP-1/ACLY脂生成轴减少大鼠脂肪组织中高脂饮食诱导的肥胖作用
Mohamed M Elseweidy,Dalia G Hagraous,Abdelmoniem A Ali et al.
Mohamed M Elseweidy et al.
Obesity is a health problem with an economic burden. This study examined the anti-obesogenic impact of caffeic acid (Caf) or resveratrol (Res) and their effect on lipogenic enzymes. Wister albino rats received high-fat diet (HFD) for 16 wee...
Harnessing therapeutic potential of bromelain and its nanoformulations: sojourn of pineapple from food to nanomedicine [0.03%]
菠萝蛋白酶及其纳米递送制剂的治疗潜力探索——从食物到药物的旅程
Rajge Rahul Ravindra,Jaskiran Kaur,Sukriti Vishwas et al.
Rajge Rahul Ravindra et al.
Background: Bromelain is a proteolytic enzyme obtained from pineapple stems, possessing diverse pharmacological properties such as antioxidant, antidiabetic, anticancer, anti-inflammatory, anthelmintic, cardioprotective, ...