Rahaman Shaik,M Shaheer Malik,Sreevani Basavaraju et al.
Rahaman Shaik et al.
Objectives: Cancer drug resistance is a multifaceted phenomenon. The present review article aims to comprehensively analyze the cellular and molecular aspects of drug resistance in cancer and the strategies employed to ov...
Seyed Hossein Hajimiri,Fatemeh Soleymani
Seyed Hossein Hajimiri
The pharmaceutical industry is poised for transformative advancements amid rapid technological developments and rising challenges. This editorial emphasizes the need to incorporate STEM (Science, Technology, Engineering, and Mathematics) di...
Advances in artificial intelligence-based technologies for increasing the quality of medical products [0.03%]
基于人工智能技术提高医疗产品质量的研究进展
Nidhi Srivastava,Sneha Verma,Anupama Singh et al.
Nidhi Srivastava et al.
Artificial intelligence (AI) is a technology that combines machine learning (ML) and deep learning. It has numerous usages in the domains of medicine and other sciences. Artificial intelligence can forecast the behavior of a drug's target p...
Therapeutic role of erythropoietin in methanol induced optic neuropathy: a systematic review [0.03%]
促红细胞生成素在甲醇性视神经病中的治疗作用：系统综述
Neda Feizi,Mahsa Mohamadzadeh-Nabiei,Hadi Vahedi et al.
Neda Feizi et al.
Purpose: Despite various therapeutic attempts, an approved treatment for Methanol-induced optic neuropathy (MION), a sight-threatening disorder, is still lacking. Erythropoietin known as an erythropoietic cytokine, posses...
Pharmacogenetic DPYD allele variant frequencies: A comprehensive analysis across an ancestrally diverse Iranian population [0.03%]
DPYD基因型变异频率的药理遗传学全面分析：伊朗多祖先人群中的研究
Negar Sarhangi,Fatemeh Rouhollah,Negar Niknam et al.
Negar Sarhangi et al.
Background: Cancer treatment has improved over the past decades, but many cancer patients still experience adverse drug reactions (ADRs). Pharmacogenomics (PGx), known as personalized treatment, is a pillar of precision m...
A synthetic curcumin-like diarylpentanoid analog inhibits rhinovirus infection in H1 hela cells via multiple antiviral mechanisms [0.03%]
一种合成的类似姜黄素的二芳基戊烷类衍生物通过多种抗病毒机制抑制H1 HeLa细胞中的鼻病毒感染
Kong Yen Liew,Hui-Yee Chee,Faridah Abas et al.
Kong Yen Liew et al.
Background: Rhinovirus (RV) infection is a major cause of common colds and asthma exacerbations, with no antiviral drug available. Curcumin exhibits broad-spectrum antiviral activities, but its therapeutic effect is limit...
Relieving postherpetic neuralgia pain via gabapentin-loaded bigels as an auspicious topical drug delivery system [0.03%]
用于治疗带状疱疹后神经痛的加巴喷丁载药双凝胶制剂作为颇具前景的局部给药系统
Wessam H Abd-Elsalam,Abdulaziz Mohsen Al-Mahallawi,Amal Makhlouf
Wessam H Abd-Elsalam
Background: Over the past decades, a substantial portion of the population worldwide has been infected with varicella zoster and most cases developed shingles. Unfortunately, shingles is usually accompanied by postherpeti...
Recent opportunities and application of gellan gum based drug delivery system for intranasal route [0.03%]
recent opportunities and application of gellan gum based drug delivery system for intranasal route用于鼻腔途径的gellan gum基药物递送系统的最近机遇和应用
Anuj Garg,Khushboo Lavania
Anuj Garg
Objectives: In the recent years, in-situ hydrogel based on gellan gum has been investigated for delivery of various drug molecules particularly to treat neurological disorders via intranasal route. The major objective of ...
One-pot synthesis of polysaccharide/gelatin amorphous hydrogels impregnated with a bioflavonoid derived from Elaeis guineensis leaf: wound healing and drug release properties [0.03%]
以非洲油棕叶来源生物类黄酮为原料的一锅法合成多糖/明胶无定形水凝胶及其伤口愈合和药物释放性能研究
Mohamad Shazeli Che Zain,Mohammed Danish,Khozirah Shaari et al.
Mohamad Shazeli Che Zain et al.
Background: Amorphous hydrogel is a strategic wound healing dressings that comprised of water, polymers and excipients with no shape. The dense cross-linked network of polymer is interspersed by the immobilized water comp...
Ameliorative effect of Melatonin on 5-Fluorouracil-induced reproductive toxicity in male rats [0.03%]
褪黑素改善5-氟尿嘧啶致雄性大鼠生殖毒性的作用研究
Darya Almasi,Sohrab Kazemi,Mohammad Hossien Asghari et al.
Darya Almasi et al.
5-Fluorouracil (5-FU) is an antimetabolite chemotherapeutic agent that can cause oxidative stress and complications in normal organs, including the reproductive system. This study was conducted to investigate the effect of melatonin (MEL) o...