Recent opportunities and application of gellan gum based drug delivery system for intranasal route [0.03%]
recent opportunities and application of gellan gum based drug delivery system for intranasal route用于鼻腔途径的gellan gum基药物递送系统的最近机遇和应用
Anuj Garg,Khushboo Lavania
Anuj Garg
Objectives: In the recent years, in-situ hydrogel based on gellan gum has been investigated for delivery of various drug molecules particularly to treat neurological disorders via intranasal route. The major objective of ...
One-pot synthesis of polysaccharide/gelatin amorphous hydrogels impregnated with a bioflavonoid derived from Elaeis guineensis leaf: wound healing and drug release properties [0.03%]
以非洲油棕叶来源生物类黄酮为原料的一锅法合成多糖/明胶无定形水凝胶及其伤口愈合和药物释放性能研究
Mohamad Shazeli Che Zain,Mohammed Danish,Khozirah Shaari et al.
Mohamad Shazeli Che Zain et al.
Background: Amorphous hydrogel is a strategic wound healing dressings that comprised of water, polymers and excipients with no shape. The dense cross-linked network of polymer is interspersed by the immobilized water comp...
Ameliorative effect of Melatonin on 5-Fluorouracil-induced reproductive toxicity in male rats [0.03%]
褪黑素改善5-氟尿嘧啶致雄性大鼠生殖毒性的作用研究
Darya Almasi,Sohrab Kazemi,Mohammad Hossien Asghari et al.
Darya Almasi et al.
5-Fluorouracil (5-FU) is an antimetabolite chemotherapeutic agent that can cause oxidative stress and complications in normal organs, including the reproductive system. This study was conducted to investigate the effect of melatonin (MEL) o...
Zvanaka Mazhandu,Tebogo Mashifana
Zvanaka Mazhandu
Global water availability has been affected by a variety of factors, including climate change, water pollution, urbanization, and population growth. These issues have been particularly acute in many parts of the world, where access to clean...
Structure based exploration of mitochondrial alpha carbonic anhydrase inhibitors as potential leads for anti-obesity drug development [0.03%]
基于结构的线粒体α碳酸酐酶抑制剂抗肥胖药物研发中的作用及其机制研究
Ipsa Padhy,Tripti Sharma,Biswajit Banerjee et al.
Ipsa Padhy et al.
Background: Obesity has emerged as a major health challenge globally in the last two decades. Dysregulated fatty acid metabolism and de novo lipogenesis are prime causes for obesity development which ultimately trigger ot...
Fatemeh Rahimi,Ali Massoudifar,Roya Rahimi
Fatemeh Rahimi
Objectives: Tobacco smoking is a worldwide health problem and one of the leading causes of premature deaths in last years. As there are lots of researches focusing on cessation strategies with attention to pharmacotherapy...
Lipid management strategies for diabetic patients align with an evidence-based guideline [0.03%]
糖尿病患者的血脂管理策略符合基于证据的指南
Mona Kargar,Noushid Zare,Aarefeh Jafarzadeh Kohneloo et al.
Mona Kargar et al.
Background: Diabetes mellitus (DM) increases the risk of cardiovascular diseases (CVD) significantly. Statins are recommended for all diabetic patients aged ≥ 40 years to alleviate this risk. ...
Glatiramer acetate in situ forming gel, a new approach for multiple sclerosis treatment [0.03%]
一种新的治疗多发性硬化症的方法：原位凝胶成型的醋酸格拉默注射液
Anahita Shobeirean,Hossein Attar,Reyhaneh Varshochian et al.
Anahita Shobeirean et al.
Background: Glatiramer acetate (GA), a commonly used treatment for multiple sclerosis (MS), requires long-term frequent injections to ensure its effectiveness. This often leads to adverse effects, patient noncompliance, a...
A review of the ethnomedicinal, phytochemical, and pharmacological properties of the Ferulago genus based on Structure-Activity Relationship (SAR) of coumarins [0.03%]
基于香豆素的结构活性关系（SAR），对Ferulago属草药、次生代谢产物和药理特性的综述研究
Farid Dabaghian,Shokoufeh Aalinezhad,Alaleh Riazati Kesheh et al.
Farid Dabaghian et al.
Background: The Ferluago W.D.J. Koch genus includes 48 accepted perennial herbs that are distributed in the Mediterranean region, Southeast Europe, Central and Middle East of Asia. These plants are widely used in folk and...
Population Pharmacokinetics of Loxoprofen and its alcoholic metabolites in healthy Korean men [0.03%]
韩国健康男性患者体内柳氮酚和其酒精代谢产物的群体药代动力学分析
Ji-Hun Jang,Ho-Suk Kang,Seung-Hyun Jeong
Ji-Hun Jang
Background: Loxoprofen has been actively used clinically to relieve musculoskeletal pain and inflammatory symptoms. However, there are few reports on quantitative pharmacokinetic (PK) prediction tools and diversity analyz...