Evaluation of clinical and safety outcomes of generic tacrolimus (Suprotac ®) versus branded tacrolimus (Prograf ®) in de novo liver transplant patients: a randomized clinical trial [0.03%]
他克莫司仿制药与原研药在肝脏移植受者中临床及安全性的评估：一项随机对照试验
Mojtaba Shafiekhani,Mohammad Amin Jafarzadeh,Mohammad Ahmadi et al.
Mojtaba Shafiekhani et al.
Background: Tacrolimus is a critical calcineurin inhibitor used in the management of liver transplant recipients. Currently, several pharmaceutical companies have developed and introduced generic formulations of Tacrolimu...
Randomized Controlled Trial
Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences. 2025 Oct 24;33(2):35. DOI:10.1007/s40199-025-00574-x 2025
Pharmaceutical additive manufacturing of a pH-responsive core-shell tablet of beta-galactosidase to treat lactase intolerance [0.03%]
用于治疗乳糖不耐受的pH响应型β-半乳糖苷酶核壳片剂的制药增材制造技术
Tahmineh Karami,Mohammad Akrami,Ismaeil Haririan et al.
Tahmineh Karami et al.
Lactose intolerance affects a significant portion of the global population. Among the proposed treatments for the disease, the main strategy is the use of Lactase, beta-galactosidase, and enzyme before consuming dairy products. The beta-gal...
Effect of blueberry extract on enhancement of radiosensitivity in non-Hodgkin lymphoma by modulating proliferation and apoptosis [0.03%]
蓝莓提取物通过调节增殖和凋亡增强非霍奇金淋巴瘤放射敏感性的效果研究
Neda Moradloo,Samaneh Arab,Hamed Rezaee Jam et al.
Neda Moradloo et al.
Background: Non-Hodgkin lymphoma, a major cancer type, is usually treated with radiotherapy but encounters challenges with resistance and toxicity. Therefore, the treatment of non-Hodgkin lymphoma needs agents to be very ...
Innovative triamcinolone acetonide microsuspension for Non-Invasive ocular management of inflammation [0.03%]
创新研制的曲安奈德微悬液用于非侵入性眼部抗炎治疗
Forouhe Zahir-Jouzdani,Sepehr Ashrafi,Zahra Ghaemmaghamian et al.
Forouhe Zahir-Jouzdani et al.
Enhancing the bioavailability of insoluble active agents in the eye through topical administration is a key focus in formulation science. This study aims to develop a microsuspension-based drug delivery system to effectively deliver anti-in...
Nanoformulations in epilepsy therapy - a systematic review of emerging strategies in status epilepticus [0.03%]
用于癫痫治疗的纳米药物配方-急性发作期新兴策略系统回顾
Nuraziemah Ahmad,Mohmad Farooq Shaikh,Mohammed Tahir Ansari et al.
Nuraziemah Ahmad et al.
Status epilepticus (SE) presents a life-threatening medical emergency condition characterized by prolonged seizures, leading to severe neuronal damage, morbidity and mortality, if not promptly treated. Immediate intervention is crucial, yet...
In vitro evaluation of CeO2 nanoparticles on doxorubicin induced cardiotoxicity: focused on oxidative stress, inflammation, apoptosis, and mitochondrial function [0.03%]
CeO2纳米颗粒对多柔比星致心毒性的体外评价：重点关注氧化应激、炎症、凋亡和线粒体功能
Fahad Alsaikhan
Fahad Alsaikhan
Background: Doxorubicin (Dox) is a chemotherapy medication used in the therapy of cancers. However, despite its killing of cancer cells, Dox is toxic to the heart and can lead to heart failure. This outcome in turn poses ...
New psychoactive substances: a multidisciplinary review of challenges and their diverse character [0.03%]
新型精神活性物质：对其多样性的多学科挑战及特征审查
Ilinca-Mihaela Marandiuc,Anca Oana Docea,Andreea Camelia Hîrjău et al.
Ilinca-Mihaela Marandiuc et al.
Background: New psychoactive substances (NPS) pose a rapidly evolving public health challenge due to their diverse chemical structures and psychoactive effects, necessitating a comprehensive understanding of their classif...
Co-delivery of SN38 and rapamycin albumin bound nanoparticles against breast Cancer [0.03%]
白蛋白结合型纳米颗粒联合递送SN38和雷帕霉素用于乳腺癌治疗
Sanaz Jamshidfar,Marzieh Ebrahimi,Reyhaneh Varshochian et al.
Sanaz Jamshidfar et al.
Background: The co-delivery of two therapeutic agents within a single nanoparticle platform offers a potential strategy to improve treatment efficacy while minimizing adverse effects. Albumin as a biocompatible carrier co...
Evaluation and comparison of the anti-proliferative and anti-metastatic effects of urolithin A and urolithin B against esophageal cancer cells: an in vitro and in silico study [0.03%]
基于体外和分子对接研究的去氢松香酸抗肝癌活性及其机制探讨
Maryam Shojaee,Mehdi Rostami,Mohammad Soukhtanloo et al.
Maryam Shojaee et al.
Introduction: Esophageal squamous cell carcinoma (ESCC) is a prevalent and lethal cancer, with traditional treatments often ineffective. This study investigates the anti-proliferative and anti-metastatic effects of natura...
The effect of Fe3O4 biosynthesized through the green synthesis of Silybum marianum and HA in the targeted delivery of 5-Fluorouracil to HCT116 cell line [0.03%]
通过乳蓟和HA绿色合成Fe3O4对HCT116细胞系靶向递送5-氟尿嘧啶的影响
Atefeh Mansuryar,Shima Bourang,Mehran Noruzpour et al.
Atefeh Mansuryar et al.
Background and objectives: The administration of 5-FU as the first chemotherapeutic agent for colorectal cancer, showed difficulties including short half-life and the development of resistance. One prominent approach to o...