The Relationship Between Melanoma Subtype and Organ-Specific Metastases: An Observational Study [0.03%]
恶性黑色素瘤亚型与转移部位关系的观察研究
Geethika Ameneni,Sabine Obagi,Ahmad Alamer et al.
Geethika Ameneni et al.
The Upgrading Clinical Subtype Classification of Basal Cell Carcinoma is Useful to Correlate With Its Histologic Subtype and Local Invasiveness [0.03%]
基底细胞癌的升级临床亚型分类有助于其组织学亚型和局部侵袭性的关联
Jungsoo Lee,Soobin Cha,Hyun-Chang Ko et al.
Jungsoo Lee et al.
Background: The existing clinical subtype classification of basal cell carcinoma (BCC) does not adequately reflect tumor invasiveness or its relationship with histologic patterns. ...
Clinical Efficacy and Scalp Microbiome Changes Induced by AMPamide-Containing Shampoo in Patients With Seborrheic Dermatitis [0.03%]
含阳离子肽洗发水治疗脂溢性皮炎患者的临床疗效及其对头皮微生物组的影响
Yi Na Yoon,Sae Hee Kim,Ji Won Lim et al.
Yi Na Yoon et al.
Background: Seborrheic dermatitis (SD) is a chronic inflammatory scalp disorder associated with Malassezia dysbiosis and increased sebum production. AMPamide has been suggested to have anti-inflammatory and sebum-regulati...
Effects of Botulinum Toxin A on Rosacea-Like Inflammation in an LL-37-Induced Rosacea Mouse Model [0.03%]
肉毒杆菌A型毒素对LL-37诱导的酒渣鼻小鼠模型中酒渣鼻样炎症的影响
Daewon Yoon,Jung Ok Lee,You Na Jang et al.
Daewon Yoon et al.
Background: Rosacea is a chronic inflammatory disorder characterized by flushing, erythema, papules/pustules, and telangiectasia. Several clinical studies have investigated the efficacy of botulinum neurotoxin A (BoNT/A) ...
Clinical Importance of Autoantibodies to SOX10 and Lamin A/C as Potential Biomarkers in Sera From Vitiligo Patients [0.03%]
自身抗体SOX10和核纤层A / C作为潜在生物标志物在白癜风患者血清中的临床意义
Jung-Hwan Kim,Hyun Jeong Ju,Dong-Wha Yoo et al.
Jung-Hwan Kim et al.
Background: The discovery and evaluation of reliable biomarkers of vitiligo are important; however, no clinically established serological markers exist for predicting the clinical prognosis of vitiligo. ...
A 11β-Hydroxysteroid Dehydrogenase Type 1 (11β-HSD1) Inhibitor, 11b-0048, Effectively Suppresses the Expression of 11β-HSD1 Activated in Cultured Keratinocytes and in Diabetic Murine Skin [0.03%]
一种选择性11β-氢化可的松脱氢酶Ⅰ型抑制剂11b-0048能够有效抑制培养的人皮肤角质形成细胞和糖尿病小鼠皮肤中11β-HSD1的激活表达
Ju Yeong Lee,Hyun Jee Hwang,Eunjung Kim et al.
Ju Yeong Lee et al.
Background: Elevated active glucocorticoids (GCs) are implicated in skin barrier dysfunction, notably in aging and diabetes. The enzyme 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) converts inactive GCs to active ...
The Role of Inflammasome in the Pathogenesis of Alopecia Areata: NLRP3 and Its Cascade Contribute to the Onset and Early Stage of Alopecia Areata [0.03%]
炎性小体在斑秃发病中的作用：NLRP3及其下游信号通路参与斑秃的起病及早发阶段病理过程
Ji-Hoon Lim,Da-Hyun Kang,Haena Moon et al.
Ji-Hoon Lim et al.
Background: The inflammasome, a multiprotein complex, is crucial in the pathogenesis of various autoinflammatory disorders. In particular, the NOD-like receptor family pyrin domain-containing 3 (NLRP3) inflammasome has re...
Topical Application of Probiotic-Derived EGF From Pediococcus pentosaceus Improves UVB-Induced Photoaging in Hairless Mice [0.03%]
枯草芽孢杆菌衍生的EGF外用改善无毛小鼠紫外线损伤诱导的皮肤光老化作用研究
Yoon Jin Roh,Yoon Hwan Lee,Sun Young Yuh et al.
Yoon Jin Roh et al.
Background: Epidermal growth factor (EGF) is widely applied in dermatology for its regenerative effects; however, its clinical utility is limited by low stability and high production costs. To overcome these limitations, ...
Baricitinib for Itch-Dominant Atopic Dermatitis: A 52-week Baricitinib Real-World Experience in Korea [0.03%]
巴利昔单抗治疗特应性皮炎患者瘙痒的疗效和安全性：一项为期52周的韩国真实世界研究
Narang Hong,Ho Eun Gwag,So Yun Park et al.
Narang Hong et al.
Background: Baricitinib is one of the front-runners among targeted agents for the treatment of atopic dermatitis (AD). Although many studies have been conducted on the real-world use of baricitinib, the sample size is oft...
Crisaborole 2% for Pediatric Periorificial Dermatitis: A Randomized, Double-Blind, Vehicle-Controlled Pilot Study [0.03%]
克利萨博罗尔治疗儿童口周皮炎二期临床试验
Ayelet Ollech,Bat-El Bar Aluma,Adi Weiss-Fink et al.
Ayelet Ollech et al.
Background: Periorificial dermatitis (POD) is a common inflammatory skin condition primarily affecting infants, children, and young women. Novel therapies such as phosphodiesterase 4 (PDE4) inhibitors provide promising no...