Sun-Ju Ahn
Sun-Ju Ahn
Seunghee Lee,Yeri Alice Rim,Juryun Kim et al.
Seunghee Lee et al.
To address the limitations of animal testing, scientific research is increasingly focused on developing alternative testing methods. These alternative tests utilize cells or tissues derived from animals or humans for in vitro testing, as we...
Taehwan Kwak,Si-Hyung Park,Siyoung Lee et al.
Taehwan Kwak et al.
This study offers a comprehensive overview of brain organoids for researchers. It combines expert opinions with technical summaries on organoid definitions, characteristics, culture methods, and quality control. This approach aims to enhanc...
Hyang-Ae Lee,Dong-Hun Woo,Do-Sun Lim et al.
Hyang-Ae Lee et al.
Cardiac organoids have emerged as invaluable tools for assessing the impact of diverse substances on heart function. This report introduces guidelines for general requirements for manufacturing cardiac organoids and conducting cardiac organ...
Kyungtae Lim,Mi-Ok Lee,Jinwook Choi et al.
Kyungtae Lim et al.
The objective of standard guideline for utilization of human lung organoids is to provide the basic guidelines required for the manufacture, culture, and quality control of the lung organoids for use in non-clinical efficacy and inhalation ...
Hye-Ran Moon,Seon Ju Mun,Tae Hun Kim et al.
Hye-Ran Moon et al.
Recent amendments to regulatory frameworks have placed a greater emphasis on the utilization of in vitro testing platforms for preclinical drug evaluations and toxicity assessments. This requires advanced tissue models capable of accurately...
Hyun Mi Kang,Dong Sung Kim,Yong Kyun Kim et al.
Hyun Mi Kang et al.
Recent advancements in organoid technology have led to a vigorous movement towards utilizing it as a substitute for animal experiments. Organoid technology offers versatile applications, particularly in toxicity testing of pharmaceuticals o...
Sun-Ju Ahn,Sungin Lee,Dayeon Kwon et al.
Sun-Ju Ahn et al.
An organoid is a self-organized three-dimensional structure derived from stem cells that mimics the structure, cell composition, and functional characteristics of specific organs and tissues and is used for evaluating the safety and effecti...
Guidelines for Packaging, Transport, and Storage of Source Cells for Organoids [0.03%]
器官oid源细胞的包装、运输和储存指南
Sungin Lee,Dayeon Kwon,Han Byeol Lee et al.
Sungin Lee et al.
This paper presents guidelines for the systematic management of packaging, storage, transportation, and traceability of source cells used for organoid research. Given the important role of source cells in organoid studies, it is important t...
Gastric Organoid, a Promising Modeling for Gastric Stem Cell Homeostasis and Therapeutic Application [0.03%]
胃类器官在胃干细胞稳态及治疗应用中的研究展望
Subin Lee,Jang-Hyun Choi,So-Yeon Park et al.
Subin Lee et al.
The elucidation of the pathophysiology underlying various diseases necessitates the development of research platforms that faithfully mimic in vivo conditions. Traditional model systems such as two-dimensional cell cultures and animal model...