Fumiaki Ishibashi,Sho Suzuki
Fumiaki Ishibashi
Colorectal cancer (CRC) is a leading cause of cancer-related deaths worldwide. Worldwide, population-based systematic screening programs for the disease, which is essential to address this burden, rely primarily on fecal immunochemical test...
Identification of Poor Prognosis-Associated Fibroblast Subpopulation Signature Genes Utilizing the Scissor Algorithm to Classify Colorectal Cancer Subtypes and Evaluate the Immune Landscape [0.03%]
利用Scissor算法识别不良预后相关成纤维细胞亚群特征基因以分类结直肠癌亚型并评估免疫图谱
Meng Wang,Jianhui Gu,Jie Zhang et al.
Meng Wang et al.
Background/aims: Colorectal cancer (CRC) shows high heterogeneity. Conventional bulk transcriptome-based classification methods fail to capture the complex tumor microenvironment of CRC, limiting precision therapy advance...
Sex-Dependent Microbial and Host Profiles Following Fecal Microbiota and Bifidobacterium longum Treatment in Stress-Induced Gut Dysbiosis [0.03%]
压力引起的小鼠肠道菌群紊乱的粪菌移植及长双歧杆菌干预的性别差异性研究
Chin-Hee Song,Nayoung Kim,Ryoung Hee Nam et al.
Chin-Hee Song et al.
Background/aims: Irritable bowel syndrome (IBS) is a chronic functional gastrointestinal disorder influenced by stress, microbial dysbiosis, and immune activation. Microbiota-directed therapies, including fecal microbiota...
Comparative Effectiveness of a Prophylactic Application for the Prevention of Postpolypectomy Bleeding in Pedunculated Colonic Polyps: A Network Meta-Analysis [0.03%]
预防带蒂结肠息肉电切术后出血的药物选择网络 meta 分析
Jae Hyun Kim,Jung Won Lee,Hyun Jung Kim et al.
Jae Hyun Kim et al.
Background/aims: Postpolypectomy bleeding (PPB) is a major complication of pedunculated colonic polyps. Various prophylactic interventions, including clips, endoloops, and epinephrine injections, have been proposed to pre...
Preclinical Analysis of Bone Marrow-Derived Stem Cell Therapy Response and Transcriptomic Overlap Analysis in a Severe Alcoholic Hepatitis Mouse Model [0.03%]
重度酒精性肝炎小鼠模型中骨髓源性干细胞治疗反应的临床前分析及转录组重叠分析
Soonchang Hong,Seul Ki Han,Mi Ra Lee et al.
Soonchang Hong et al.
Background/aims: Severe alcoholic hepatitis (SAH) is a life-threatening form of alcoholic liver disease resulting in high short-term mortality. Mesenchymal stem cells (MSCs) have potent immunomodulatory effects and have b...
Comparison of Long-Term Outcomes between Curative and Non-Curative Resection after Endoscopic Submucosal Dissection for Superficial Esophageal Squamous Cell Carcinoma [0.03%]
内镜下黏膜下剥离术治疗浅表性食管鳞癌的治愈性与非治愈性切除的长期结局比较
Minkyu Choi,Byeong Yun Ahn,Quanxin Zheng et al.
Minkyu Choi et al.
Background/aims: Given the limited data on the long-term outcomes of non-curative resection (non-CR) following endoscopic submucosal dissection (ESD) for patients with superficial esophageal squamous cell carcinoma (SESCC...
Randomized, Double-Blind, Active-Controlled, Parallel, Phase 3 Clinical Trial for Evaluating the Efficacy and Safety of Zastaprazan in Patients with Gastric Ulcers [0.03%]
泽拉普唑治疗胃溃疡患者的有效性和安全性的随机、双盲、阳性对照、平行组间比较的III期临床试验
Kyung Sik Park,Hyun-Soo Kim,Jung-Hwan Oh et al.
Kyung Sik Park et al.
Background/aims: Zastaprazan (JP-1366) is a novel potassium-competitive acid blocker with a fast onset and prolonged duration. This study aimed to assess the efficacy and safety of zastaprazan versus lansoprazole in patie...
Lean Metabolic Dysfunction-Associated Steatotic Liver Disease and Dementia Risk: A High-Risk Phenotype beyond Body Mass Index [0.03%]
代谢功能异常相关性脂肪肝病与痴呆风险增加有关：超越体质指数的高危表型
Seogsong Jeong
Seogsong Jeong
Editorial
Gut and liver. 2026 Jan 15;20(1):3-4. DOI:10.5009/gnl250606 2026
Unmasking Kidney Risk in Steatotic Liver Disease: A Call for Metabolic Precision [0.03%]
揭开脂肪肝病肾脏风险的面纱：代谢精准医学的呼唤
Chan-Young Jung
Chan-Young Jung
Editorial
Gut and liver. 2026 Jan 15;20(1):1-2. DOI:10.5009/gnl250617 2026
Is It Time to Replace the Duodenal Self-Expandable Metal Stent with Endoscopic Ultrasonography-Guided Gastroenterostomy for Malignant Gastric Outlet Obstruction in Patients with Pancreatic Cancer? [0.03%]
在胰腺癌患者中，是否应该用内镜超声引导胃肠造口术替代十二指肠金属支架治疗恶性幽门狭窄？
Hsiao-Sheng Lu,Kuei-Chuan Lee,Ming-Chih Hou
Hsiao-Sheng Lu
Malignant gastric outlet obstruction (MGOO) occurs in 2% to 25% of patients with pancreatic ductal adenocarcinoma (PDAC) who do not undergo surgical intervention. Over the past decade, duodenal self-expandable metal stent (D-SEMS) has been ...
Review
Gut and liver. 2026 Jan 2. DOI:10.5009/gnl250354 2026