Semen Discoloration Following Upadacitinib Therapy in Patients with Inflammatory Bowel Disease [0.03%]
乌帕替尼治疗炎症性肠病患者的精液变色现象
Jeong Hwa Lee,Hae Chang Cho,Jae Myung Cha et al.
Jeong Hwa Lee et al.
Upadacitinib, a selective Janus kinase 1 inhibitor, has demonstrated efficacy in moderate-to-severe inflammatory bowel disease (IBD). Although its safety profile has been well established, genitourinary adverse events have rarely been repor...
Real-World Application of a Machine Learning-Based Early Recurrence Model for Guiding Adjuvant Chemotherapy Use in Patients with Gallbladder Cancer [0.03%]
基于机器学习的早期复发模型在指导胆囊癌辅助化疗应用中的真实世界研究
Won-Gun Yun,Youngmin Han,Yoon Soo Chae et al.
Won-Gun Yun et al.
Background/aims: Although recent randomized controlled trials have reported the efficacy of adjuvant chemotherapy for resected biliary tract cancer, discrepancies remain between recommendations and real-world practice. Th...
Adverse Events Associated with Advanced Therapy Compared with Conventional Therapy in Patients with Inflammatory Bowel Disease: A Common Data Model Analysis [0.03%]
与炎症性肠病患者接受传统治疗相比，先进疗法相关的不良事件：常用数据模型分析
Hyoung Il Choi,Myoungsuk Kim,Jung Rock Moon et al.
Hyoung Il Choi et al.
Background/aims: Although clinical trials have reported adverse events (AEs) associated with advanced therapies (ATs) in patients with inflammatory bowel disease (IBD), the risks of AEs may be underestimated due to the se...
Metabolic Dysfunction-Associated Fibrosis 5 Score and the Risk of Liver-Related Events in the General Population [0.03%]
代谢紊乱相关肝纤维化5分评分与一般人群的肝脏事件风险之间的关系
Byeong Geun Song,Goeun Park,Myung Ji Goh et al.
Byeong Geun Song et al.
Background/aims: The metabolic dysfunction-associated fibrosis 5 (MAF-5) tool has been proposed for identifying individuals at high risk of liver fibrosis, but its ability to predict liver-related events (LREs) remains un...
A Phase III, Randomized, Double-Blind, Active-Controlled, Multicenter Study Evaluating the Safety and Efficacy of Tegoprazan for the Prevention of Peptic Ulcer in Patients on Continuous Long-Term Treatment with Nonsteroidal Anti-Inflammatory Drugs [0.03%]
一项在非甾体抗炎药长期治疗的患者中评估替加环素预防 peptic ulcer的安全性和有效性的 III 期、随机、双盲、阳性对照、多中心研究
Sang Gyun Kim,Tae-Oh Kim,Sung Woo Jung et al.
Sang Gyun Kim et al.
Background/aims: Long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs) increases the risk of peptic ulcers. Tegoprazan, a novel potassium-competitive acid blocker, provides rapid and potent inhibition of acid pro...
Real-World Data on the Efficacy and Safety of Fexuprazan in Patients with Gastroesophageal Reflux Disease: Interim Analysis of Post-Marketing Surveillance [0.03%]
富克斯拉唑治疗胃食管反流病有效性和安全性的真实世界数据：上市后监测中期分析
Jie-Hyun Kim,Ki Hong Lee,Woo Seok Lee et al.
Jie-Hyun Kim et al.
Background/aims: Fexuprazan, a novel potassium-competitive acid blocker, has emerged as a promising alternative to proton pump inhibitors for the treatment of gastroesophageal reflux disease (GERD). Although its efficacy ...
Effects of Chemotherapy on Survival Outcomes in Older Patients with Metastatic Pancreatic Cancer: A Nationwide Population-Based Study [0.03%]
化疗对老年转移性胰腺导管腺癌患者生存结局的影响：基于全国人口的队列研究
Kangju Son,Byung Kyu Park,Chan Su Park et al.
Kangju Son et al.
Background/aims: Clinical data on chemotherapy outcomes in older patients with pancreatic cancer are limited. This population-based study aimed to evaluate the effects of chemotherapy on survival outcomes in older patient...
Optimal Sampling Site for the Diagnosis of Helicobacter pylori Infection with the Rapid Urease Test: A Prospective Cohort Study [0.03%]
快速尿素酶试验诊断幽门螺杆菌感染的最佳取材部位：前瞻性队列研究
Yuri Kim,Heonwoo Lee,Ga Hee Kim et al.
Yuri Kim et al.
Background/aims: The rapid urease test (RUT) is widely used as a first-line method because of its rapidity and low cost. We aimed to determine the diagnostic accuracy of the RUT versus immunohistochemical (IHC) staining o...
Endoscopic Ultrasound-Guided Drainage of an Intra-Abdominal Abscess in a Patient with Crohn's Disease [0.03%]
内镜超声引导下的腹腔脓肿引流术在克罗恩病患者中的应用
Shin Gil Kim,Jingu Kang,Young Woo Chae et al.
Shin Gil Kim et al.
Data-Informed Intuition in Hepatology: Integrating Evidence, Context, and Clinical Reasoning [0.03%]
数据驱动的肝病学直觉：证据、背景与临床推理的整合
Jin Dong Kim,Mi Na Kim,Do Young Kim
Jin Dong Kim
Artificial intelligence and data-driven models are changing hepatology, but expert clinical judgment remains essential. Liver diseases are complex and evolve over time, requiring reasoning that links numerical data with clinical context. We...