Unveiling miR-451a and miR-142-3p as prognostic markers in non-small cell lung cancer via small extracellular vesicle liquid biopsy [0.03%]
通过小型细胞外囊泡液体活检在非小细胞肺癌中揭示范miR-451a和miR-142-3p作为预后标志物的作用
Miranda Burdiel,Ana Arauzo-Cabrera,Julia Jiménez et al.
Miranda Burdiel et al.
Single-cell multi-omics analysis of the tumour microenvironment for colorectal cancer liver metastasis [0.03%]
结直肠癌肝转移肿瘤微环境的单细胞多组学分析
Jiao Guan,Mingwei Guo,Min Hu et al.
Jiao Guan et al.
P2X7R deficiency alleviates cardiac senescence by enhancing mitophagy via the HuR/TRIM26/NR4A1 axis [0.03%]
P2X7受体缺乏通过HuR/TRIM26/NR4A1轴增强线粒体自噬缓解心脏衰老
Yixin Zhou,Xin Zhong,Zhijie Mao et al.
Yixin Zhou et al.
Background: Ageing is a significant risk factor for pathophysiological alterations in the heart, but the intrinsic mechanisms by which these occur have yet to be fully elucidated. Purinergic 2×7 receptor (P2X7R) is impor...
Revolutionising acute aortic syndrome diagnosis: The role of artificial intelligence in non-contrast computed tomography [0.03%]
人工智能在非对比度CT急性主动脉综合征诊断中的作用
Qiqi Wang,Yujian Hu,Yan-Jie Zhou et al.
Qiqi Wang et al.
The insider's perspective: The intracellular complosome and immune cell dynamics in cancer [0.03%]
insiders'视角：癌症的细胞内complosome和免疫细胞动力学
Alexandra Bennion,Joanne Lysaght,Niamh Lynam-Lennon
Alexandra Bennion
Complement is increasingly recognised as a driver and modulator of antitumour immunity, with context-dependent effects across T cells, myeloid subsets, stromal elements and tumour cells. Although best known for pathogen clearance and membra...
Two pathogens, one disease: Rethinking leprosy diversification through ancient and modern genomes [0.03%]
两种病原体，一种疾病：通过古代和现代基因组重新思考麻风病的分化问题
Maria Lopopolo,Charlotte Avanzi,Nicolás Rascovan
Maria Lopopolo
Lactylation in colorectal cancer: Unveiling novel mechanisms in metabolism, progression and therapeutic targeting [0.03%]
结直肠癌中的乳酰化：代谢、进展及治疗靶点的新机制研究
Ming Liu,Weiwei Li,Yi Ji et al.
Ming Liu et al.
Background: Colorectal cancer is a leading cause of cancer mortality characterised by a unique metabolic microenvironment and complex interactions with the gut microbiota. Lactylation, a novel post-translational modificat...
Milk fat globule-EGF factor 8/ATP-binding cassette subfamily E member 1 axis maintains mitophagy flux homeostasis to suppress ferroptosis in acute pancreatitis [0.03%]
急性胰腺炎中维持线粒体自噬稳态以抑制铁死亡的乳脂肪球表皮生长因子因子8/ATP结合盒转运蛋白亚家族E成员1轴
Yifan Ren,Yuxuan Lu,Qing Cui et al.
Yifan Ren et al.
Background: Acute pancreatitis (AP) is a severe inflammatory disorder in which mitochondrial dysfunction and ferroptosis critically drive acinar cell injury. Our previous work suggested a protective role for exogenous mil...
Decreased adipokine CTRP4 in CAD patients: CTRP4 attenuates atherosclerosis via inhibition of RAGE and TLR4 [0.03%]
冠心病患者体内抗动脉粥样硬化因子CTRP4减少及其功能研究
Xinyi Shu,Feifei Li,Jiawei Chen et al.
Xinyi Shu et al.
Background: C1q/TNF-related proteins (CTRPs) belong to the adipokine family. Here, we aimed to assess the relation of CTRP4 levels in serum and perivascular adipose tissue (PVAT) with coronary artery disease (CAD), and in...
HepAssis2® bioartificial liver system in treating acute-on-chronic liver failure patients: Findings from a phase 1 randomised, open-label clinical trial [0.03%]
一种治疗急性肝衰竭患者的生物人工肝脏系统（HepAssis2®）：一项1期随机开放标记临床试验的结果
Zibiao Zhong,Wenjin Liang,Yong&#x;an Dai et al.
Zibiao Zhong et al.