Pharmacokinetics of micronized and water dispersible palmitoylethanolamide in comparison with standard palmitoylethanolamide following single oral administration in male Sprague-Dawley rats [0.03%]
微粉化和水中可分散的棕榈酰乙醇胺与标准棕榈酰乙醇胺单次口服给药在雄性Sprague-Dawley大鼠体内的药动学比较研究
S Mehkri,K G Dinesh,G Ashok et al.
S Mehkri et al.
Background: Palmitoylethanolamide (PEA) is an endogenous fatty acid amide signaling molecule that may indirectly modulate the endocannabinoid system. It has poor water solubility and, therefore, is not readily absorbed in...
Comparative Study
Indian journal of pharmacology. 2025 Jul 1;57(4):219-225. DOI:10.4103/ijp.ijp_964_24 2025
Potent antiurolithiasis activity of Phaseolus vulgaris aqueous extract and its nano-formulation on ethylene glycol-induced urolithiasis in rats [0.03%]
Phaseolus vulgaris的水提取物及其纳米配方对大鼠诱导尿路结石的抗尿路结石活性研究
S Jayaprakash,C Sankar,G Sivakumar
S Jayaprakash
Introduction: The proper allopathy treatment is unavailable, and the recurrent is very commonly observed for urolithiasis; therefore, there is a need to find out phytochemical options to prevent and treat urolithiasis. Ou...
Vipul Bharati,Sandhya Rajaram,Ajay Prakash et al.
Vipul Bharati et al.
Hemoglobin estimation by the classical method should be adhered to for understanding anemia following lead exposure: Old is gold [0.03%]
铅中毒后的贫血仍然需要依靠传统的方法来估计血红蛋白水平:经典依旧闪烁着光芒
Sumanpreet Kaur,Deepak Kumar,Rajasri Bhattacharyya et al.
Sumanpreet Kaur et al.
Acute accidental methotrexate poisoning: Fatal consequences - An Indian experience [0.03%]
急性意外甲氨蝶呤中毒:一项印度经验研究及其致命后果
Mauli M Shah,Priya K Ghoghara,Shree Dhanani et al.
Mauli M Shah et al.
Methotrexate (MTX) is a versatile drug used in various fields, including oncology and rheumatology, acting by inhibitory effects on DNA synthesis and cellular replication. While low-dose MTX is a first-line treatment for rheumatoid arthriti...
Portal vein thrombosis as a complication of Eltrombopag used in the treatment of immune thrombocytopenia in a patient of chronic liver disease [0.03%]
慢性肝病患者使用艾曲波帕治疗免疫性血小板减少症的并发症门静脉血栓形成
Sangita D Kamath,Manish Kumar,Sudip Saha et al.
Sangita D Kamath et al.
Eltrombopag is a thrombopoietin receptor agonist which is used an off-label treatment for thrombocytopenia in chronic liver disease (CLD). It is US Food and Drug Administration approved in the treatment of immune thrombocytopenia. However, ...
Effects of zinc status on cell cycle and viability: An in vitro study in monocytes (THP-1) and muscle (Rhabdomyosarcoma) cells [0.03%]
锌状态对细胞周期和存活的影响:单核细胞(THP-1)和肌肉瘤细胞的体外研究
Sarath Babu Srivalliputturu,Srinivasa Reddy Yathapu
Sarath Babu Srivalliputturu
Monocyte and muscle cells are considered Zn reservoirs and sensitive to Zn fluctuations, especially in terms of viability. The current study aimed to understand the effect of Zn sufficiency and deficiency on THP-1 monocyte and rhabdomyosarc...
A simple patch test (empty tablet cover patch test) demonstrating ornidazone as offending agent in a patient of fixed drug eruption: Report of a clinical case, a new modified technique and systematic review of literature [0.03%]
一项简单的斑贴试验(空药片皮试)检测出固定性药物疹患者的 offendin 为联苯胺中间体:临床病例、新的改良技术和系统文献综述
R Balamurugan,Phulen Sarma,Prabhakaran Nagendran et al.
R Balamurugan et al.
A 49-year-old male presented with the complaints of sudden-onset redness and watering of both the eyes following the intake of fixed drug combination of ofloxacin-ornidazole for diarrhea. Following this, he developed redness of both the lip...
Global prescription patterns and practices: Utilization of statins in diabetes management across nations [0.03%]
全球处方模式和实践:各国在糖尿病管理中使用他汀类药物的情况
Smruti Besekar,Sangita Jogdand,Satyawan Singh Patel
Smruti Besekar
Cardiovascular disease (CVD) poses a significant risk for individuals with type 2 diabetes mellitus (T2DM), and statins are integral in preventing such complications. However, global statin prescription practices often diverge from clinical...
Therapeutic potential of novel tin metal complex of embelin isolated from Embelia ribes fruits [0.03%]
来自Embela ribes果实中的新型金属锡配位化合物Embeline的治疗潜力
Ruchi Singh,Durga K Mewara
Ruchi Singh
Background: Dried Embelia ribes berries can be used to extract Embelin (2,5-Dihydroxy-3-undecylcyclohexa-2,5-diene -1,4-dione), a herbal p-benzoquinone derived from general quinones. This plant shows potential for scienti...