Valproate-induced hyperammonemic delirium in a patient with bipolar affective disorder: A clinical caution [0.03%]
双相情感障碍患者出现丙戊酸诱导高氨血症性谵妄的临床警戒案例
Shruti Gupta,Sanyam Tyagi,Sumit Rana et al.
Shruti Gupta et al.
Pathum Sookaromdee,Viroj Wiwanitkit
Pathum Sookaromdee
A rare drug reaction: Toxic epidermal necrolysis following polymyxin B administration in a post-Bentall procedure [0.03%]
布entall术后应用多粘菌素B致中毒性表皮坏死松解症1例
Bhavin B Patel,Rachana B Patel,Nisarg R Hajariwala et al.
Bhavin B Patel et al.
Polymyxin B is a last-resort antibiotic used to treat multidrug-resistant (MDR) Gram-negative infections. While nephrotoxicity and neurotoxicity are well-documented, severe dermatologic adverse reactions such as toxic epidermal necrolysis (...
Adverse drug reaction due to concomitant vaccine administration of Covishield and Hepatitis-B in a patient with multidrug allergies [0.03%]
新冠Shield和乙肝疫苗联合使用导致多药过敏患者药物不良反应
Abhishek Sharma,Gulnaz Bano
Abhishek Sharma
A 33-year-old male patient having multiple drug allergies but well tolerated to Hepatitis-B vaccine (vaccinated in April 2016) on receiving a second booster dose of Hepatitis-B vaccine (GeneVac-B) within 10 days of Covishield first dose imm...
Rare manifestation of paclitaxel-induced cardiotoxicity: A case of restrictive cardiomyopathy in an elderly breast cancer patient [0.03%]
紫杉醇引起的心脏毒性罕见表现——一位老年乳腺癌患者的限制型心肌病病例报告
Kumar Masum,Sandeep Srinivas,Balakeshwa Ramaiah
Kumar Masum
Paclitaxel, a widely used taxane in the treatment of breast and other solid tumors, rarely causes cardiovascular complications such as restrictive cardiomyopathy and often underrecognized. A 78-year-old woman with estrogen receptor/progeste...
Reporting and critical appraisal of evidence-based research: Making the journal club most effective [0.03%]
基于证据的研究的报告和批判性评价：使期刊俱乐部最有效
Rashmi Ranjan Das,Akash Bang
Rashmi Ranjan Das
Evidence-based research (EBR) has become a cornerstone in the scientific, medical, and social sciences disciplines, informing decision-making processes and advancing knowledge across various fields. Evidence-based practice emphasizes integr...
Fluoxetine inhibits severe acute respiratory syndrome coronavirus 2 replication in vitro [0.03%]
氟西汀体外抑制严重急性呼吸系统综合症冠状病毒2的复制
Yethindra Vityala,Tugolbai Tagaev,Elmira Mainazarova et al.
Yethindra Vityala et al.
No drugs exist that effectively inhibit the cell entry or genomic replication of severe acute respiratory syndrome coronavirus 2 (SARSCoV2). This study evaluated the effects of fluoxetine on SARSCoV2 replication in vitro. Cytotoxicity of bo...
Efficacy and safety of remdesivir for patients with severe acute respiratory syndrome coronavirus 2 infection: A systematic review of randomized controlled trials [0.03%]
瑞德西韦治疗严重急性呼吸系统综合征冠状病毒2型感染的疗效和安全性：随机对照试验的系统评价
Jitendra Meena,Amit Agarwal,Amit Sandhu et al.
Jitendra Meena et al.
In view of the pandemic of coronavirus disease 2019 (COVID-19), there is a need to identify a specific antiviral therapy. We performed this systematic review to assess the efficacy of remdesivir in the treatment of COVID-19. We searched thr...
A cross-sectional clinical analysis on diabetic foot ulcer and associated risk management [0.03%]
糖尿病足溃疡的风险因素及风险管理的临床分析
Mohamed Arsath Shamsudeen,Subash C B Gopinath,Mohamad Zahin Hafiz Zulkiple
Mohamed Arsath Shamsudeen
Background: Diabetic foot ulcers (DFUs) are a serious complication of diabetes mellitus, leading to significant morbidity and an increased risk of amputation. This study aimed to determine the clinical profile and associa...
Hexarelin promotes the survival of retinal ganglion cells after optic nerve transection [0.03%]
Hexarelin促进视神经切断后视网膜节细胞的存活
Kevin Bing Shui Chow
Kevin Bing Shui Chow
Objective: Hexarelin is a growth hormone secretagogue receptor type 1a agonist with a potent anti-apoptotic effect. We studied the neuroprotective effect of hexarelin on the survival of retinal ganglion cells (RGCs) in th...