A hairy encounter: Black hairy tongue after linezolid therapy in an ecthyma patient [0.03%]
一例依托泊苷致黑毛舌的不良反应事件
Parth Rathi,Prakhar Srivastava,Niti Khunger et al.
Parth Rathi et al.
Jitendra Singh,Nilesh Kumar,Kailash Kumar et al.
Jitendra Singh et al.
Heparin, a commonly used anticoagulant, has been associated with several cutaneous adverse effects, including skin necrosis, bruising/ecchymosis, urticaria, angioedema, red plaques, nodular lesions, and allergic contact dermatitis. Bullous ...
K Jagadish Kumar,Shivani Kundur,Lalitha Vasudha Bulusu et al.
K Jagadish Kumar et al.
Metoclopramide is a dopamine-2 antagonist and is generally used as an antiemetic in clinical practice. Extrapyramidal reactions are the important adverse effects of metoclopramide which are reported in 0.2% of cases. In young children, the ...
Internal validation of researcher-centered translational model: A mixed-method study [0.03%]
基于研究者的转化医学模型的内部验证——一项混合方法研究
S Supriya,Shantanu Patil,Bagavandas Mappillairaju
S Supriya
The study aimed to examine the impact of the researcher-centered Basic Fit Translational Model and Delivery Design framework on outcomes such as visualization, progression, and self-reflection. We collected data through questionnaires, with...
Efficacy and safety of dextromethorphan-bupropion combination (AXS-05) in the treatment of depression: A systematic review and network meta-analysis [0.03%]
右美沙芬-安非他酮联合治疗抑郁症的疗效和安全性：系统评价和网络meta分析
J V Ashwin,Mohit Kumar Shahi,Astha Singh et al.
J V Ashwin et al.
This network meta-analysis evaluated the efficacy and safety of the dextromethorphan-bupropion combination (AXS-05) in treating major depressive disorder (MDD). Data were retrieved from multiple databases, including PubMed, Embase, Scopus, ...
Comparison of renal function of the patients receiving linagliptin or vildagliptin in uncontrolled type 2 diabetes mellitus: An observational study in the backdrop of the COVID-19 pandemic [0.03%]
与COVID-19大流行背景下未经控制的2型糖尿病患者接受利格列汀或维格列汀治疗的肾功能比较：一项观察性研究
Sailayee Chaudhuri,Supreeti Biswas,Sandip Mukhopadhyay et al.
Sailayee Chaudhuri et al.
Background: Dipeptidyl peptidase 4 (DPP-4) inhibitors are primarily excreted renally. Linagliptin is an exception with excretion primarily through enterohepatic system and is expected to have a better renal profile, thoug...
Observational Study
Indian journal of pharmacology. 2025 Jul 1;57(4):254-261. DOI:10.4103/ijp.ijp_492_24 2025
Human oral pharmacokinetics of 4-hydroxy isoleucine and dosage simulation studies for predicting its pharmacodynamics in diabetes [0.03%]
4-羟异亮氨酸的人体口腔药代动力学及剂量模拟研究以预测其在糖尿病中的药效学效应
Thirumurthy Velpandian,Lakshminarayanan Gowtham,Madhu Nath et al.
Thirumurthy Velpandian et al.
Introduction: 4-hydroxy isoleucine (4-HIL), a potent glucose-lowering agent and insulin secretagogue, is widely available in nutraceutical market as fenugreek seed extract formulations. This study aims to elucidate the or...
Appropriateness of antimicrobial therapy in medical wards of a tertiary care referral hospital and its effect on antibiotic consumption and in-hospital mortality [0.03%]
三级医疗保健转诊医院内科病房抗菌药物治疗的适宜性及其对抗菌药物使用量和住院死亡率的影响
Challa Madhuri,Deepanjali Surendran,Apurba Sankar Sastry et al.
Challa Madhuri et al.
Objectives: This study was conducted to find out the appropriateness of antimicrobial therapy in Medical wards of a tertiary care referral hospital in South India. Other objectives were to study the association between ap...
Co-treatment of trigonelline and everolimus synergistically prevented chronic steatohepatitis induced by fast food diet and thioacetamide in a novel murine nonalcoholic steatohepatitis model [0.03%]
trigonelline和everolimus联合治疗可协同预防高脂饮食和硫乙酰胺诱导的慢性steatohepatitis
Raghu Rai Sharma,Love Sharma,Haroon Rashid et al.
Raghu Rai Sharma et al.
Objectives: Nonalcoholic steatohepatitis (NASH) is a strong risk factor for end-stage liver disease. Trigonelline (TG) is a plant alkaloid with anti-oxidant, anti-dyslipidemic, and anti-insulin resistance activities. Ever...
Molecular docking and in vitro anticancer evaluation of potential compounds derived from Indonesian sponge Agelas nakamurai [0.03%]
印度尼西亚海绵Agelas nakamurai衍生物潜在抗肿瘤化合物的分子对接及体外评价研究
Fitri Budiyanto,Bustanussalam Bustanussalam,Yatri Hapsari et al.
Fitri Budiyanto et al.
Objective: This study evaluated the anticancer activity (in silico and in vitro) of compounds derived from the Agelas nakamurai collected from Indonesian waters against the triple-negative breast cancer cancer cell line M...