Safety assessment of dexmedetomidine: Real-world adverse event analysis from the Food and Drug Administration Adverse Events Reporting System public dashboard [0.03%]
右美托咪定安全性评价:基于美国食品药品监督管理部门不良事件公开报告系统分析
Yi Yin,Jie Jiang,Youpeng Jin
Yi Yin
Dexmedetomidine (DEX), as a widely used medication for sedation, its usage has increased significantly. The concerns about its side effects remain, making a thorough safety evaluation necessary. Data on adverse drug events related to DEX fr...
Dzana Lukac,Tanja Vojinovic,Pinaki Dutta et al.
Dzana Lukac et al.
Background: In this century, antimicrobial resistance (AMR) presents a major public health problem, because it is a leading cause of death worldwide. Antimicrobial resistance is caused by the overprescription of antibioti...
Impact of the timing of antibiotic prophylaxis on the surgical site infections in patients undergoing elective general surgery [0.03%]
择期普通外科手术患者抗生素预防性用药时间对其手术部位感染的影响研究
Aayush Lakkanna,Guguloth Rajender,Yashwant Raj Sakaray et al.
Aayush Lakkanna et al.
Introduction: Surgical site infections are one of the major challenges in surgical practice. The antibiotic prophylaxis, though scientific, still lacks clarity on the timing of the administration of the drugs. ...
Randomized Controlled Trial
Indian journal of pharmacology. 2025 Sep 1;57(5):334-337. DOI:10.4103/ijp.ijp_797_24 2025
Sodium glucose co-transporter 2 inhibitors safety depending on their adverse drug reactions and glucose monitoring parameters in type 2 diabetes mellitus [0.03%]
钠葡萄糖共转运体2抑制剂的安全性取决于其不良反应及血糖监测指标的2型糖尿病患者中的研究
Dhanush Bellapu,Ronald Darwin
Dhanush Bellapu
Introduction: SGLT2 inhibitors have a wide extent of restorative movement and higher chance of hypoglycemia because of their affront autonomous action in treating type 2 diabetes. SGLT2 inhibitors have great security and ...
Synergistic activity of meropenem and sulbactam against carbapenem-resistant Acinetobacter baumannii [0.03%]
美罗培南/舒巴坦联合治疗碳青霉烯类耐药的鲍曼不动杆菌体外试验研究
I Amruthavarshini,Deepashree Rajshekar,Raghavendra Rao et al.
I Amruthavarshini et al.
Objective: The purpose of this study was to determine the in vitro synergistic effect of meropenem and sulbactam drug combinations through checkerboard assay against Carbapenem-resistant Acinetobacter baumannii (CRAB) to ...
In silico drug repurposing targeting fusion and nucleoprotein of human metapneumovirus: A step toward pandemic preparedness [0.03%]
针对人副流感病毒融合蛋白和核蛋白的药物再利用的计算机辅助研究:迈向大流行病应对措施的第一步
Harshita Rajput,Gajendra Choudhary,Hadiya Siddiqui et al.
Harshita Rajput et al.
Background: Human metapneumovirus (HMPV) is an emerging respiratory pathogen affecting children, elderly individuals, and immunocompromised patients. Despite its disease burden, no antiviral treatment has been approved to...
Reporting negative Ames test results for Indian Acorus calamus L., rhizome, extracts, and beta asarone [0.03%]
印度Acorus calamus L.根茎提取物及β-阿萨醇的Ames试验阴性报告
D B Anantha Narayana,Alka Mukne
D B Anantha Narayana
Objective: Acorus calamus L. (Sweet Flag), known in India as "Vacha," is widely used in traditional medicine, particularly for cognitive enhancement in infants. While traditionally considered safe, β-asarone - a key cons...
Pharmacokinetic study of the synthetic cannabinoid, 5F-MDMB-PICA, in male Wistar rats [0.03%]
关于合成大麻素5F-MDMB-PICA在雄性Wistar大鼠体内药代动力学的研究
Elkhatim Hassan Abdelgadir,Bashayer Mohammed Alharbi,Noor Hassan Dammas et al.
Elkhatim Hassan Abdelgadir et al.
Background: This research focused on establishing a highly sensitive and reliable gas chromatography-mass spectrometry (GC-MS) method for detecting and quantifying 5F-MDMB-PICA in rat plasma, as well as thoroughly assessi...
Leprosy research registry a global perspective: Need of hour for a newer vision in India towards zero leprosy [0.03%]
全球麻风病研究登记簿:印度实现零麻风病的新视角需求不容忽视
Pugazhenthan Thangaraju,Krishnapriya Neelambaran,Bikash Medhi
Pugazhenthan Thangaraju
Abhijit Saha,Subhra Dhar,Swarnali Maiti et al.
Abhijit Saha et al.