Concentration and Preservation of Very Low Abundance Biomarkers in Urine, such as Human Growth Hormone (hGH), by Cibacron Blue F3G-A Loaded Hydrogel Particles [0.03%]
Cibacron Blue F3G-A负载的水凝胶颗粒浓缩并保存尿液中的痕量生物标志物（如人绒毛膜生长激素(hGH)）
Claudia Fredolini,Francesco Meani,K Alex Reeder et al.
Claudia Fredolini et al.
Urine is a potential source of diagnostic biomarkers for detection of diseases, and is a very attractive means of non-invasive biospecimen collection. Nonetheless, proteomic measurement in urine is very challenging because diagnostic biomar...
Proton-Resistant Quantum Dots: Stability in Gastrointestinal Fluids and Implications for Oral Delivery of Nanoparticle Agents [0.03%]
抗质子量子点：胃肠液中的稳定性及其对纳米颗粒药物口服递送的意义
Aaron M Mohs,Hongwei Duan,Brad A Kairdolf et al.
Aaron M Mohs et al.
Semiconductor quantum dots (QDs) have shown great promise as fluorescent probes for molecular, cellular and in-vivo imaging. However, the fluorescence of traditional polymer-encapsulated QDs is often quenched by proton-induced etching in ac...
Xiaoming Sun,Zhuang Liu,Kevin Welsher et al.
Xiaoming Sun et al.
Two-dimensional graphene offers interesting electronic, thermal, and mechanical properties that are currently being explored for advanced electronics, membranes, and composites. Here we synthesize and explore the biological applications of ...
Leslie Au,Yeechi Chen,Fei Zhou et al.
Leslie Au et al.
This paper describes a facile method of preparing cubic Au nanoframes with open structures via the galvanic replacement reaction between Ag nanocubes and AuCl(2) (-). A mechanistic study of the reaction revealed that the formation of Au nan...
Carbon Nanotubes in Biology and Medicine: In vitro and in vivo Detection, Imaging and Drug Delivery [0.03%]
生物医学中的碳纳米管：体外及体内探测、成像和药物输送
Zhuang Liu,Scott Tabakman,Kevin Welsher et al.
Zhuang Liu et al.
Carbon nanotubes exhibit many unique intrinsic physical and chemical properties and have been intensively explored for biological and biomedical applications in the past few years. In this comprehensive review, we summarize the main results...
Two-photon Luminescence Imaging of Bacillus Spores Using Peptide-functionalized Gold Nanorods [0.03%]
用于芽孢杆菌孢子两光子发光成像的肽功能化金纳米棒
Wei He,Walter A Henne,Qingshan Wei et al.
Wei He et al.
Bacillus subtilis spores (a simulant of Bacillus anthracis) have been imaged by two-photon luminescence (TPL) microscopy, using gold nanorods (GNRs) functionalized with a cysteine-terminated homing peptide. Control experiments using a pepti...
In Vivo Therapeutic Silencing of Hypoxia-Inducible Factor 1 Alpha (HIF-1α) Using Single-Walled Carbon Nanotubes Noncovalently Coated with siRNA [0.03%]
利用非共价作用将siRNA包覆在单壁碳纳米管上的方法实现其在体内对缺氧诱导因子(HIF)-1α的沉默效应
Geoffrey Bartholomeusz,Paul Cherukuri,John Kingston et al.
Geoffrey Bartholomeusz et al.
A new approach is described for delivering small interfering RNA (siRNA) into cancer cells by noncovalently complexing unmodified siRNA with pristine single-walled carbon nanotubes (SWCNTs). The complexes were prepared by simple sonication ...