Inhibition of Wnt signaling by Frizzled7 antibody-coated nanoshells sensitizes triple-negative breast cancer cells to the autophagy regulator chloroquine [0.03%]
Frizzled7抗体包被的纳米壳通过抑制Wnt信号使三阴性乳腺癌细胞对自噬调节剂氯喹敏感化治疗
Jianxin Wang,Megan N Dang,Emily S Day
Jianxin Wang
Despite improvements in our understanding of the biology behind triple-negative breast cancer (TNBC), it remains a devastating disease due to lack of an effective targeted therapy. Inhibiting Wnt signaling is a promising strategy to combat ...
Bioengineering of nano metal-organic frameworks for cancer immunotherapy [0.03%]
用于癌症免疫治疗的纳米金属有机框架的生物工程学研究
Gaowei Chong,Jie Zang,Yi Han et al.
Gaowei Chong et al.
Immunotherapy techniques, such as immune checkpoint inhibitors, chimeric antigen receptor (CAR) T cell therapies and cancer vaccines, have been burgeoning with great success, particularly for specific cancer types. However, side effects wit...
Superhydrophobic, photo-sterilize, and reusable mask based on graphene nanosheet-embedded carbon (GNEC) film [0.03%]
基于石墨烯纳米片嵌入式碳膜的超疏水、光杀菌和可重复使用口罩
Zezhou Lin,Zheng Wang,Xi Zhang et al.
Zezhou Lin et al.
The 2019 coronavirus disease (COVID-19) has affected more than 200 countries. Wearing masks can effectively cut off the virus spreading route since the coronavirus is mainly spreading by respiratory droplets. However, the common surgical ma...
Long-term live-cell microscopy with labeled nanobodies delivered by laser-induced photoporation [0.03%]
用于激光诱导光穿孔递送纳米抗体的长期活细胞显微镜观测技术
Jing Liu,Tim Hebbrecht,Toon Brans et al.
Jing Liu et al.
Fluorescence microscopy is the method of choice for studying intracellular dynamics. However, its success depends on the availability of specific and stable markers. A prominent example of markers that are rapidly gaining interest are nanob...
Photoacoustic-immune therapy with a multi-purpose black phosphorus-based nanoparticle [0.03%]
基于多功能黑磷纳米粒子的光声免疫疗法
Fanchu Zeng,Huan Qin,Liming Liu et al.
Fanchu Zeng et al.
Effective therapeutic strategies to precisely eradicate primary tumors with minimal side effects on normal tissue, inhibit metastases, and prevent tumor relapses, are the ultimate goals in the battle against cancer. We report a novel therap...
Qiang Zhang,Zhuo Ao,Nan Hu et al.
Qiang Zhang et al.
The interstitial space, a widespread fluid-filled compartment throughout the body, is related to many pathophysiological alterations and diseases, attracting increasing attention. The vital role of interstitial space in malaria infection an...
Na Lu,Liqian Wang,Min Lv et al.
Na Lu et al.
Graphene-based nanomaterials have emerged as a novel type of materials with exceptional physicochemical properties and numerous applications in various areas. In this review, we summarize recent advances in studying interactions between gra...
Plasmonic molecular assays: Recent advances and applications for mobile health [0.03%]
等离子体分子检测技术：最新进展及移动医疗应用
Tao Yu,Qingshan Wei
Tao Yu
Plasmonics-based biosensing assays have been extensively employed for biomedical applications. Significant advancements in use of plasmonic assays for the construction of point-of-care (POC) diagnostic methods have been made to provide effe...
Hui Li,Shaoying Wang,Zhouxiang Ji et al.
Hui Li et al.
Nanotubes are miniature materials with significant potential applications in nanotechnological, medical, biological and material sciences. The quest for manufacturing methods of nano-mechanical modules is in progress. For example, the appli...
Efficient renal clearance of DNA tetrahedron nanoparticles enables quantitative evaluation of kidney function [0.03%]
高效的肾清除DNA四面体纳米颗粒可实现肾脏功能的定量评估
Dawei Jiang,Hyung-Jun Im,Madeline E Boleyn et al.
Dawei Jiang et al.
DNA tetrahedron nanostructure (DTN) is one of the simplest DNA nanostructures and has been successfully applied for biosensing, imaging, and treatment of cancer. To facilitate its biomedical applications and potential clinical translation, ...