Aiyatullah Shah,Nawab John Dar,Qazi Parvaiz Hassan et al.
Aiyatullah Shah et al.
Neurodegeneration is progressive loss of functional and structural integrity of the central nervous system. Neurodegenerative disorders are yet without any reliable therapy because the neurons of the central nervous system have limited abil...
Breakdown of Blood-Brain and Blood-Spinal Cord Barriers During Acute Methamphetamine Intoxication: Role of Brain Temperature [0.03%]
急性甲氨蝶呤中毒时血脑屏障和脊髓屏障的破坏：脑部温度的作用
Eugene A Kiyatkin,Hari S Sharma
Eugene A Kiyatkin
Methamphetamine (METH) is a powerful and often-abused stimulant with potent addictive and neurotoxic properties. While it is generally believed that structural brain damage induced by METH results from oxidative stress, in this work we pres...
Effect of Environmental Extremely Low-Frequency Electromagnetic Fields Exposure on Inflammatory Mediators and Serotonin Metabolism in a Human Neuroblastoma Cell Line [0.03%]
极低频电磁场暴露对人神经母细胞瘤细胞炎性介质及血清素代谢的影响
Marcella Reale,Chiara D&#x;Angelo,Erica Costantini et al.
Marcella Reale et al.
Exposure to environmental extremely low-frequency electromagnetic fields (ELF-EMF) in everyday life is increasing and it is a matter of great debate whether exposure to ELF-EMF can be harmful to human health. The neuropathology and symptoms...
'Non-Criteria' Neurologic Manifestations of Antiphospholipid Syndrome: A Hidden Kingdom to be Discovered [0.03%]
抗磷脂综合征的''非标准''神经精神表现：一个有待发现的领域
Md Asiful Islam,Fahmida Alam,Mohammad Amjad Kamal et al.
Md Asiful Islam et al.
Neurological manifestations or disorders associated with the central nervous system are among the most common and important clinical characteristics of antiphospholipid syndrome (APS). Although in the most recently updated (2006) APS classi...
Weihong Pan,Abba J Kastin
Weihong Pan
Here we summarize three aspects of our understanding of the interactions of cytokines and neurotrophic peptides/proteins with the blood-brain and bloodspinal cord barriers (BBB): (a) pharmacokinetic analysis that has been reported for nativ...
Abba J Kastin,Weihong Pan
Abba J Kastin
Pertinent to pandemic obesity, the discovery of endogenous peptides that affect the ingestion of food has led to the question of how these ingestive peptides exert their actions in the brain. Whereas peripheral sources provide a ready reser...
An Overview on the Role of α -Synuclein in Experimental Models of Parkinson's Disease from Pathogenesis to Therapeutics [0.03%]
α-突触核蛋白在帕金森病实验模型中的作用概述：从发病机制到治疗学
Hayate Javed,Mohammad Amjad Kamal,Shreesh Ojha
Hayate Javed
Parkinson's disease (PD) is a devastating and progressive movement disorder characterized by symptoms of muscles rigidity, tremor, postural instability and slow physical movements. Biochemically, PD is characterized by lack of dopamine prod...
Geoffrey Burnstock
Geoffrey Burnstock
Purinergic signalling, i.e. ATP as an extracellular signalling molecule and cotransmitter in both peripheral and central neurons, is involved in the physiology of neurotransmission and neuromodulation. Receptors for purines have been cloned...
Potential Use of Nanomedicine for Drug Delivery Across the Blood-Brain Barrier in Healthy and Diseased Brain [0.03%]
纳米药物在健康和疾病大脑中穿越血脑屏障递送药物的潜在应用
Barbara Ruozi,Daniela Belletti,Francesca Pederzoli et al.
Barbara Ruozi et al.
The research of efficacious non-invasive therapies for the treatment of brain diseases represents a huge challenge, as people affected by disorders of the central nervous system (CNS) will significantly increase. Moreover, the blood-brain b...
Neuroprotection by Methylene Blue in Cerebral Global Ischemic Injury Induced Blood-Brain Barrier Disruption and Brain Pathology: A Review [0.03%]
甲苯胺蓝对脑全局缺血性损伤的神经保护作用：综述文章
Lars Wiklund,Aruna Sharma,Hari Shanker Sharma
Lars Wiklund
Transient global ischemic cerebral injury is a consequence of cardiac arrest and accounts for approximately 450,000 annual deaths with a mortality of approximately 90%. Serious morbidity follows for many of the survivors and up to 16% of pa...