Updates on Therapeutics in Clinical Trials for Spinal Cord Injuries: Key Translational Applications of Human Embryonic Stem Cells-Derived Neural Progenitors [0.03%]
脊髓损伤临床试验中的治疗新进展：人胚胎干细胞来源神经前体细胞的关键转化应用
Habiba Zeb,Ishaq Nasib Khan,Iqbal Munir et al.
Habiba Zeb et al.
Injuries to the spinal cord often have devastating physiological impacts due to the organ's vital role in neuro-impulse communications between muscles and the brain. Spinal Cord Injuries (SCIs) have recently been estimated to affect up to 8...
Treatment Possibilities for Psychosis in Parkinson's Disease with An Emphasis on the Newly Approved Drug: Pimavanserin [0.03%]
帕金森病 psychosis 的治疗选择——重点关注新药 pimavanserin的应用
Zsofia Majlath,Izabella Obal,Laszlo Vecsei
Zsofia Majlath
Parkinson's disease (PD) is a progressive neurodegenerative disorder with prominent motor and non-motor symptoms. Psychosis develops in over 40% of PD patients and it is one of the most distressing symptoms for patients and caregivers alike...
Syed Sayeed Ahmad,Salman Akhtar,Qazi Mohammad Sajid Jamal et al.
Syed Sayeed Ahmad et al.
AD is a progressive and irreversible neurodegenerative disease and the most common cause of dementia in the elderly population. Βeta- amyloid cascade formation along with several cytoskeleton abnormalities succeeding to the hyperphosphoryl...
Selective Serotonin Reuptake Inhibitors and Serotonin and Noradrenaline Reuptake Inhibitors Improve Cognitive Function in Partial Responders Depressed Patients: Results from a Prospective Observational Cohort Study [0.03%]
选择性血清素再摄取抑制剂和血清素去甲肾上腺素再摄取抑制剂可改善部分抑郁患者的功能认知：一项前瞻性队列研究的结果
Sabrina Castellano,Andrea Ventimiglia,Salvatore Salomone et al.
Sabrina Castellano et al.
Background: Major Depressive disorder (MDD) is often accompanied by cognitive deficits, involving attention, learning, memory and executive functioning. Selective Serotonin Reuptake Inhibitors (SSRIs) and Serotonin and No...
Prediction of Anti-Diabetic Drugs as Dual Inhibitors Against Acetylcholinesterase and Beta-Secretase: A Neuroinformatics Study [0.03%]
预测抗糖尿病药物作为乙酰胆碱酯酶和β-分泌酶双重抑制剂的研究：一种神经信息学方法
Sibhghatulla Shaikh,Syed Mohd Danish Rizvi,Tabinda Suhail et al.
Sibhghatulla Shaikh et al.
An increasing number of research evidences indicate linkage between type 2 diabetes mellitus (T2DM) and Alzheimer's disease (AD); the two most common diseases of aging. In addition, T2DM and AD also share some common pathophysiological feat...
Neuroprotective Effects of Cannabidiol in Hypoxic Ischemic Insult. The Therapeutic Window in Newborn Mice [0.03%]
cannabidiol缺氧缺血损伤的神经保护作用及新生小鼠的有效治疗时间窗口分析
Nagat Mohammed,Maria Ceprian,Laura Jimenez et al.
Nagat Mohammed et al.
Background: A relevant therapeutic time window (TTW) is an important criterion for considering the clinical relevance of a substance preventing newborn hypoxic-ischemic (HI) brain damage. ...
Editorial: (Thematic Issue) Novel Concepts on the Blood-Brain Barrier and Brain Pathology. New Therapeutic Approaches [0.03%]
特刊·编辑部论文：关于血脑屏障和脑病理学的新概念及新治疗策略
Hari S Sharma,Stephen D Skaper,Aruna Sharma
Hari S Sharma
Commentary : Hypothesis Focused Ultrasound and NXY-059 in Experimental Cerebral Ischemia: A New Therapeutic Opportunity? [0.03%]
评论文章：实验性脑缺血的聚焦超声和NXY-059：新的治疗机会？
Burak Yulug,Lütfü Hanoglu,Feysel Yalcin Yamaner et al.
Burak Yulug et al.
José V Lafuente,Garazi Bermudez,Lorena Camargo-Arce et al.
José V Lafuente et al.
Cerebral syndromes related to high-altitude exposure are becoming more frequent as the number of trips to high altitudes has increased in the last decade. The commonest symptom is headache, followed by acute mountain sickness (AMS) and high...
Cornelia M Wilson,Gohar Mushtaq,Mohammad A Kamal et al.
Cornelia M Wilson et al.
Endoproteolysis is a normal post-translational process in the eukaryotic cell that plays a role in protein evolution allowing protein catabolism and the generation of amino acids. Endoproteolytic cleavage regulates many crucial cellular pro...