The Resting-State Functional Connectivity of the Default Mode Networks in Patients With Obstructive Sleep Apnea-Hypopnea Syndrome [0.03%]
阻塞性睡眠呼吸暂停低通气综合征患者的默认模式网络静息态功能连接研究
Ting Chen,Ming Yang,Bin Liu et al.
Ting Chen et al.
Obstructive sleep apnea-hypopnea syndrome (OSAHS) is normally linked to cognitive and functional dysfunctions. In this study, we explored the resting-state functional connectivity (rsFC) in the default mode network (DMN) to show the mechani...
Subacute Fluoxetine Reduces Signs of Hippocampal Damage Induced by a Single Convulsant Dose of 4-Aminopyridine in Rats [0.03%]
次急性氟西汀减少4-氨基吡啶致惊厥剂量所致大鼠海马损害的迹象
Ahmed A Shiha,Rubén Fernández de la Rosa,Mercedes Delgado et al.
Ahmed A Shiha et al.
Background: Epilepsy is a central disorder associated with neuronal damage and brain hypometabolism. It has been reported that antidepressant drugs show anticonvulsant and neuroprotective effects in different animal model...
Neuropathic Pain and Lung Delivery of Nanoparticulate Drugs: An Emerging Novel Therapeutic Strategy [0.03%]
神经病理性疼痛和纳米颗粒药物的肺部递送：一种新兴的治疗策略
Nazrul Islam,Muzaffar Abbas,Shafiqur Rahman
Nazrul Islam
Neuropathic pain is a chronic neurological disorder affecting millions of people around the world. The currently available pharmacologic agents for the treatment of neuropathic pain have limited efficacy and are associated with dose related...
Desmoteplase for Acute Ischemic Stroke: A Systematic Review and Metaanalysis of Randomized Controlled Trials [0.03%]
关于急性缺血性卒中的系统评价和随机对照试验的荟萃分析：有关 deserotrol 的疗效及安全性
Ahmed Elmaraezy,Abdelrahman Ibrahim Abushouk,Soha Saad et al.
Ahmed Elmaraezy et al.
Introduction: There is an unmet need to develop better treatments for acute ischemic stroke (AIS). Desmoteplase is a vampire bat saliva-derived analogue of human tissue plasminogen activator. It has higher fibrin selectiv...
Mitochondrial Dysfunctions in Bipolar Disorder: Effect of the Disease and Pharmacotherapy [0.03%]
双相障碍的线粒体功能异常：疾病和药物治疗的影响
Tereza Cikankova,Ekaterina Sigitova,Martina Zverova et al.
Tereza Cikankova et al.
Exact pathophysiological mechanisms of bipolar disorder have not been sufficiently clarified. We review the evidence of mitochondrial dysfunctions on the relation between both disease and pharmacotherapy. Mitochondria produce the most of en...
Cerebrospinal-fluid Alzheimer's Disease Biomarkers and Blood-Brain Barrier Integrity in a Natural Population of Cognitive Intact Parkinson's Disease Patients [0.03%]
帕金森病患者中阿尔茨海默病脑脊液生物标志物与血脑屏障完整性的关系研究
Claudio Liguori,Enrica Olivola,Mariangela Pierantozzi et al.
Claudio Liguori et al.
Background: Cerebrospinal-fluid (CSF) Alzheimer's Disease (AD) biomarkers have been extensively studied in Parkinson's Disease (PD). Although reduced CSF beta-amyloid1-42 (Aβ42) levels have been associated with cognitive...
Analysis of Adverse Events Related to 720 Cases of Neural Progenitor Cell Transplantation [0.03%]
720例神经干细胞移植相关不良事件分析
Suqing Qu,Weipeng Liu,Hui Yang et al.
Suqing Qu et al.
Background: Cell therapies have shown to be able to improve neurological functions to some extent for patients with refractory central nervous system (CNS) diseases or damages. Meanwhile, increasing attention has been dra...
A Feature-Free 30-Disease Pathological Brain Detection System by Linear Regression Classifier [0.03%]
一种基于线性回归分类器的无特征脑病理病变检测系统
Yi Chen,Ying Shao,Jie Yan et al.
Yi Chen et al.
Aim: Alzheimer's disease patients are increasing rapidly every year. Scholars tend to use computer vision methods to develop automatic diagnosis system. (Background) In 2015, Gorji et al. proposed a novel method using pse...
Functional Connectivity Analysis of Brain Default Mode Networks Using Hamiltonian Path [0.03%]
基于哈密顿路径的默认模式脑网络的功能连接分析
Zhuqing Jiao,Kai Ma,Huan Wang et al.
Zhuqing Jiao et al.
The aim of this study is to introduce Hamiltonian path to analyze functional connectivity of brain default mode networks (DMNs). Firstly, the brain DMNs in resting state are constructed with the employment of functional Magnetic Resonance I...
Neuroprotective Effects of an Erythropoietin-Derived Peptide in PC1 2 Cells under Oxidative Stress [0.03%]
一种新型的促红细胞生成素衍生肽对氧化应激下PC12细胞的神经保护作用
Seung-Jun Yoo,Bongki Cho,Chanil Moon et al.
Seung-Jun Yoo et al.
Erythropoietin (EPO) has been shown to be a key cytokine in the production of erythrocytes from erythroblasts. Recently, attempts have been made to adopt EPO as a drug target for neuroprotection in selected neurological pathologies. In the ...