Vindeburnol Induces Neuroprotection in Rat Traumatic Brain Injury via Adrenergic Receptor Antagonism [0.03%]
肾上腺素受体拮抗剂 Vindeburnol 对大鼠创伤性脑损伤的神经保护作用
Mikhail Ivanov,Lyudmila Borets,Elmira Yakupova et al.
Mikhail Ivanov et al.
Introduction/objective: Traumatic Brain Injury (TBI) causes substantial neurological deficits and remains a major therapeutic challenge. This study aimed to evaluate the neuroprotective properties of Vindeburnol (VIND), a...
Pathogenic Protein Post-Translational Modifications in Alzheimer's Disease: Mechanisms and Therapeutic Strategies [0.03%]
阿尔茨海默病致病蛋白翻译后修饰的机制与治疗策略
A Vijayalakshmi,V Prabhakar
A Vijayalakshmi
Background: Alzheimer's Disease (AD) pathology involves much more than just Amyloid- Beta (Aβ) and tau (Tau) deposition. A broad network of Post-Translational Modifications (PTMs) drives pathogenic protein conformations ...
Effect of 3',4'-Dihydroxyflavonol on Cortex Oxidant/Antioxidant System and Transmitter Levels in Brain Ischemia-Reperfusion [0.03%]
3,4-二羟基黄酮醇对脑缺血再灌注皮层氧化/抗氧化系统及神经递质的影响
Lemanur Soysal,Ebru Kubra Uzdil,Tugce Aladag et al.
Lemanur Soysal et al.
Introduction: Survivors of global cerebral ischemia (GCI) are at a high risk of developing neurological disorders. Cerebral infarction resulting from GCI may lead to neuronal loss and subsequent brain damage. In the prese...
Effects of Hesperetin Early Intervention on Brain Neurons and Microglia in APPswe/PS1dE9 Mice [0.03%]
hesperetin早期干预对APPswe/PS1dE9双转基因小鼠脑神经元和小胶质细胞的影响
Nan Wang,Hao Wen,Ying Sun et al.
Nan Wang et al.
Introduction: Neuroinflammation and microglial dysfunction play central roles in the pathogenesis of Alzheimer's disease (AD). This study investigated whether early intervention with hesperetin, a citrus flavonoid, could ...
Effect of Dual-task Exercise on Cognition and Dual-task Cost in the Elderly with Mild Cognitive Impairment: A Randomized Pilot Study [0.03%]
双任务训练对轻度认知障碍老年人认知功能及双任务成本影响的随机对照试点研究
Mariana Rocha Alves,Ana Carolina de Mello Alves Rodrigues,Rodolfo Tinini et al.
Mariana Rocha Alves et al.
Introduction: Dual-task (DT) training may enhance cognition and function in older adults with mild cognitive impairment (MCI). Whether virtual reality (VR)-based DT exercise offers advantages over traditional strength-bas...
Transcription Factor Pet-1/FEV as a Potential Therapeutic Target in Anxiety and Depressive Disorders [0.03%]
焦虑和抑郁障碍中的转录因子Pet-1/FEV的潜在治疗靶点研究
Juhee Lim
Juhee Lim
Introduction: Serotonergic dysfunction contributes to anxiety and depressive disorders not only through altered neurotransmission but also via disruptions in developmental programming, circuit integration, stress responsi...
Neurotoxicity Linked to Nitrous Oxide (Galaxy Gas) Recreation: An Overview of Clinical Evidence [0.03%]
与笑气（伽马气体）相关的神经毒性：临床证据综述
Rajkapoor Balasubramanian,Naina Mohamed Pakkir Maideen,Krishnaveni Kandasamy et al.
Rajkapoor Balasubramanian et al.
Nitrous oxide (N2O), known as laughing gas, is a colorless, low-volume gas that has become commonly used in busy maternity wards, emergency rooms, and dental offices. It provides an introduction to the principles and practices of anesthesia...
Neuropsychiatric Sequelae of COVID-19: A Systematic Review of Acute and Prolonged Effects [0.03%]
新冠COVID-19的神经精神后遗症：急性及长期影响系统综述
Mohammed Ahmed Ismail Alhasawi,Umme Farwa,Ghazala Muteeb et al.
Mohammed Ahmed Ismail Alhasawi et al.
Introduction: Following the global emergence of SARS-CoV-2, it has become evident that COVID-19 can produce persistent, multisystemic symptoms known as "long COVID." Neurocognitive and neuropsychiatric symptoms are report...
The Role of Presynaptic Cytomatrix Protein Bassoon (BSN) in Tau Pathology and Propagation [0.03%]
bassoon在tau病理和传播中的作用
Wei Jet Oo,Wei Tong Sia,Jia Yee Lee et al.
Wei Jet Oo et al.
Neurodegenerative disorders have become a global health threat following a prolonged lifespan, with the majority involving the accumulation and propagation of pathological tau. Tau oligomers can migrate to presynaptic terminals and interact...
Therapeutic Potential of Macroalgae- and Microalgae-Derived Bioactive Compounds in Parkinson's Disease [0.03%]
微藻和大型海藻源生物活性化合物在帕金森病治疗中的潜力
Jia Yee Lee,Luis Wei Cheng Lim,Chiew Yen Wong et al.
Jia Yee Lee et al.
Marine macroalgae and microalgae are valuable natural sources of diverse bioactive compounds, such as carbohydrates, phenolics, phycobiliproteins, carotenoids, fatty acids, and vitamins. These compounds exhibit a variety of biological activ...