The Therapeutic Effects of Dietary Supplements on OCD: A Narrative Review [0.03%]
饮食补充剂对OCD的治疗作用：叙述性综述
Ghazal Tavakoli,Leili Sharif Bakhtiar,Amir Ghanbari et al.
Ghazal Tavakoli et al.
Introduction: Sufficient amounts of nutrients have been considered important in the pathophysiology of obsessive-compulsive disorder (OCD). In recent years, many studies have examined alleviating symptoms of neurological ...
Amyotrophic Lateral Sclerosis: Therapeutic Innovations and Evolving Regulatory Approaches [0.03%]
肌萎缩侧索硬化症的治疗创新与监管措施的演变
Gautam Singh,Samarendra Singh,Atreyee Sarkar et al.
Gautam Singh et al.
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder characterized by progressive degeneration of upper and lower motor neurons, leading to muscle weakness, paralysis, and respiratory failure. Despite extensive research...
Pathogenic Proteins Driving ALS Pathogenesis: Molecular Mechanisms and Translational Therapeutic Perspectives [0.03%]
驱动ALS发病的致病蛋白：分子机制与转化治疗观点
Harshpreet Kaur,Mandeep Kaur,Gopal Krishna Sethi et al.
Harshpreet Kaur et al.
Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease characterized by the progressive degeneration of motor neurons, with protein aggregation as a central pathological hallmark. Key pathogenic proteins, including TDP-43,...
Early Anti-CD20 and CNS Penetrant BTK Inhibition to Enhance OPC-Driven Remyelination in Multiple Sclerosis [0.03%]
早期的抗CD20和穿透中枢神经系统的BTK抑制作用可增强多发性硬化症中少突胶质前体细胞驱动的脱髓鞘修复作用
N Vivekanandan,M V Kumudhavalli,M Kumar
N Vivekanandan
Disability in Multiple Sclerosis (MS) increasingly accrues through Progression Independent of Relapse Activity (PIRA), driven by compartmentalized inflammation in Chronic Active Lesions (CALs) such as Paramagnetic Rim Lesions (PRLs) and Slo...
The Role of Helicobacter pylori CagA Protein in Inhibiting Amyloid Protein Aggregation [0.03%]
幽门螺旋杆菌蛋白CagA抑制淀粉样蛋白质聚集的作用机制研究
Ava Watson,Michael Shahid,Mohamed Eldeeb
Ava Watson
Amyloids are β-sheet-rich protein aggregates with various implications in biology. Beyond their functional contributions, such as biofilm formation, amyloids are best known for their involvement in a number of human pathologies, including ...
Cannabidiol in Digital Fatigue: Neuroadaptive Mechanisms and Therapeutic Perspectives on Chronic Screen Exposure [0.03%]
大麻二酚在数字疲劳中的作用：慢性屏幕暴露的神经适应机制和治疗前景
Yash Kalra,Shikha Baghel Chauhan,Indu Singh et al.
Yash Kalra et al.
Introduction: Digital Era Fatigue (DEF) is a contemporary neurobehavioral syndrome characterized by cognitive weariness, affective instability, sleep disturbances, and physiological stress caused by continuous screen and ...
Mitochondrial Dysfunction in Parkinson's Disease: Diagnostic and Therapeutic Advances [0.03%]
帕金森病的线粒体功能障碍：诊断和治疗进展
Gang Wu,Xiao-Lin Dong,Rui Li et al.
Gang Wu et al.
Parkinson's Disease (PD) is a neurodegenerative disorder in which mitochondrial dysfunction plays a central role in pathogenesis. This review summarizes key mitochondrial abnormalities involved in PD, including respiratory chain impairment,...
Understanding the OMA1-DELE1-HRI Axis and PINK1-parkin-mediated Mitophagy in Parkinson's Disease [0.03%]
帕金森病中OMA1-DELE1-HRI轴和PINK1-parkin介导的线粒体自噬机制
Shalini Singh,Anisha Sharma,Ravi Kumar Rajan et al.
Shalini Singh et al.
Introduction: Mitochondrial dysfunction plays a crucial role in the pathogenesis of Parkinson's disease (PD). PINK1-Parkin-mediated mitophagy is a quality-control system for mitochondria that protects neurons by getting r...
Bridging Gaps in Postpartum Depression Research: Pathways to Personalized Medicine in Women's Mental Health [0.03%]
产后抑郁症研究中的缺口及女性精神健康个性化医疗的路径
Harshpreet Kaur,Neha Sharma,Joy Das et al.
Harshpreet Kaur et al.
Postpartum depression (PPD) is a prevalent and serious mental health disorder that affects nearly 15% of women after childbirth. It disrupts maternal well-being, infant development, and family relationships, and often remains underdiagnosed...
Bcl-2 as a Double-edged Sword for the Treatment of Multiple Sclerosis: A Systematic Review [0.03%]
Bcl-2在多发性硬化治疗中的双刃剑作用：系统性综述
Naser-Aldin Lashgari,Fatemeh Badrabadi,Negar Rouhollahi et al.
Naser-Aldin Lashgari et al.
Introduction: Multiple sclerosis (MS) is a chronic immune-mediated neurodegenerative disease that involves inflammation, demyelination, and neuronal loss. The B-cell lymphoma 2 (Bcl-2) protein family regulates intrinsic a...