Emergence of terbinafine-resistant Trichophyton indotineae dermatophytosis in a familial cluster in Taiwan: Successful management with prolonged oral itraconazole [0.03%]
台湾一例特比萘芬耐药色真菌病家族聚集病例：延长口服伊曲康唑成功治疗白色念珠菌皮肤癣病
Han-Tang Wang,Meng-Ling Li,Wan-Lin Wu et al.
Han-Tang Wang et al.
The novel pyridine-fused quinolinone PQ-L5 exhibits antibacterial effects and enhances β-lactam activity by targeting PBP2a in methicillin-resistant Staphylococcus aureus [0.03%]
新型吡啶并喹啉酮衍生物PQ-L5具有抗菌活性并能够通过靶向耐甲氧西林金黄色葡萄球菌的pbp2a增强β-内酰胺类药物的作用
Wei Feng,Qian Yuan,Xiaowen Wang et al.
Wei Feng et al.
Background: Infections caused by methicillin-resistant Staphylococcus aureus (MRSA) are becoming increasingly difficult to treat because of the resistance of this pathogen to multiple drugs and its ability to form biofilm...
Molecular mechanisms and targets underlying immune evasion by human cytomegalovirus [0.03%]
人巨细胞病毒免疫逃逸的分子机制及靶点研究进展
Yitian Shen,Liang Zhang,Xiangyang Xue et al.
Yitian Shen et al.
Human cytomegalovirus (HCMV) establishes lifelong latency in humans largely through the evolution of sophisticated immune evasion strategies that allow it to escape recognition and clearance by the host immune system. While significant prog...
Chronicity and quality of life in Chikungunya virus infection: a cross-sectional study in Barranquilla, Colombia [0.03%]
慢性丘凯宁热病毒感染与生活质量之间的关系：哥伦比亚巴兰基拉市的横断面研究
Jorge Acosta-Reyes,Rafael Tuesca,Edgar Navarro-Lechuga et al.
Jorge Acosta-Reyes et al.
Chikungunya virus (CHIKV) infection is the second most widespread arboviral disease after dengue, and a significant number of patients suffer from a spectrum of chronic symptoms. Our objective was to estimate the prevalence of chronic CHIKV...
Efficacy and safety of ten-day bismuth quadruple therapy for first-line anti-Helicobacter pylori infection in the elderly- A multicenter real-world report [0.03%]
老年人首次根除幽门螺杆菌十日铋四联疗法的疗效和安全性——一项多中心真实世界研究报告
Kuo-Hsuan Huang,Wei-Chen Tai,Feng-Woey Tsay et al.
Kuo-Hsuan Huang et al.
Background: Aging may influence the effectiveness of Helicobacter pylori (H. pylori) eradication. The purpose of this study was to evaluate the efficacy and safety of 10-day bismuth quadruple therapy as a first-line treat...
Regulatory Networks in Helicobacter pylori: The Roles of Two-Component Systems and CsrA in Stress Adaptation [0.03%]
幽门螺杆菌的调节网络：双组分系统和CsrA在应激适应中的作用
Pei-Yun Kuo,Cheng-Yen Kao
Pei-Yun Kuo
Helicobacter pylori (H. pylori) is a major human pathogen, infecting nearly half of the global population. It has evolved remarkable adaptability to the harsh gastric environment, contributing to gastrointestinal diseases and gastric cancer...
Javanicin inhibits the secretion of hepatitis B virus particles thorough the proteasome-dependent degradation of core protein [0.03%]
爪哇酸通过泛素蛋白酶体系统降解HBV核心蛋白而抑制乙肝病毒颗粒的分泌
Nayeon Park,Gwang-Hoon Ko,Yun Seo Park et al.
Nayeon Park et al.
Background: Hepatitis B virus (HBV) is the primary cause of liver disease. Nucleot(s)ide analogues such as Entecavir are commonly used to treat HBV infection; however, although these drugs attenuate the virus, they are no...
Detection of haptoglobin gene deletion and antibodies against haptoglobin in a patient with severe anaphylactic transfusion reaction [0.03%]
血浆输注发生严重过敏反应患者的血红素结合蛋白基因缺失和抗血红素结合蛋白的检测
Kao-Yu Chang,Kuan-Hua Chu,Mei-Hwa Lin et al.
Kao-Yu Chang et al.
An immunochromatographic device to detect antibodies for rapid diagnosis of human angiostrongyliasis in whole-blood and cerebrospinal fluid samples [0.03%]
一种免疫层析装置可检测全血和脑脊液样本中的抗体从而快速诊断人类管圆线虫病
Patcharaporn Boonroumkaew,Lakkhana Sadaow,Nongnapas Kanchanangkul et al.
Patcharaporn Boonroumkaew et al.
Background: Human angiostrongyliasis is caused by the rat lung worm, Angiostrongylus cantonensis and is often a cause of eosinophilic meningitis (EOM) or meningoencephalitis. Humans are infected by consuming infective lar...
Influence of climate change on prevalence of pollen sensitization in northern Taiwan [0.03%]
气候变化对台湾北部居民花粉过敏的影响研究
Yu-Jung Liang,Bor-Luen Chiang,Chun-Min Kang et al.
Yu-Jung Liang et al.
Background: Pollen sensitization is not as common as mite sensitization in Taiwan. The dearth of regional aeropalynological studies and relevant clinical analyses has, therefore, led to an underestimation of the prevalenc...