Microbial profiles in non-leptospirosis acute undifferentiated febrile illness: Associations with clinical parameters and implications for diagnosis [0.03%]
非钩体病急性发热患者的微生物组特征及其与临床参数的关系及诊断意义
Pavaret Sivapornnukul,Umaporn Limothai,Sasipha Tachaboon et al.
Pavaret Sivapornnukul et al.
Background: Acute undifferentiated febrile illness (AUF) remains a challenge in medical diagnosis. This study aimed to investigate the microbial profiles of non-leptospirosis AUF patients from Sisaket province, an endemic...
The clinical significance of positive acid-fast bacilli smear in respiratory specimens from patients completing anti-tuberculosis treatment [0.03%]
抗结核治疗结束患者的呼吸道标本涂片阳性的临床意义
Ping-Huai Wang,Wan-Lun Wu,Hsin-Ni Huang et al.
Ping-Huai Wang et al.
Purpose: The clinical significance of positive acid-fast bacilli (AFB) by microscopy smear in respiratory specimens remains poorly understood in patients with a history of successfully treated pulmonary tuberculosis (PTB)...
Extracellular vesicles of Mucor lusitanicus reveal virulence-associated protein cargo [0.03%]
葡萄牙粘帚霉 extracellular vesicle 含有与致病相关蛋白质货物
Sándor Kiss-Vetráb,Áron Péter,Kitti Bauer et al.
Sándor Kiss-Vetráb et al.
In this study, we report the first proteomic characterization of extracellular vesicles (EVs) in a Mucorales species. EV cargo of Mucor lusitanicus contains multiple virulence-associated and biomarker-relevant proteins, supporting a potenti...
Therapeutic strategies for and clinical outcomes in iliopsoas muscle abscess: A systematic review and meta-analysis [0.03%]
髂腰肌脓肿的治疗策略及临床疗效的系统评价和meta分析
Wan-Ling Cheng,Chuan-Ju Lin,Shu-Ting Huang et al.
Wan-Ling Cheng et al.
This systematic review and meta-analysis evaluated therapeutic strategies for iliopsoas muscle abscess (IPA). Overall treatment success and mortality rates were 80.4% and 8.3%, respectively, with mortality escalating in complex cases. Modal...
Doxycycline versus azithromycin as combination therapy in the empirical treatment of community-acquired pneumonia in an intensive care unit - A retrospective propensity score-matched cohort study [0.03%]
多西环素与阿奇霉素作为社区获得性肺炎经验治疗联合疗法的效果:一项回顾性倾向得分匹配队列研究
Sin Man Lam,Hoi Ping Shum
Sin Man Lam
Introduction: Community-acquired pneumonia constitutes a significant burden to healthcare systems. While international guidelines recommend beta-lactam plus macrolide in treating severe community-acquired pneumonia, doxyc...
Clinical outcomes in patients hospitalized for COVID-19 in the periods of non-Omicron and Omicron variant dominance [0.03%]
非奥密克戎株和奥密克戎株优势流行时期COVID-19住院患者临床结局分析
Yi-Jhen Hsieh,Bing-Chen Wu,Shih-Wei Huang et al.
Yi-Jhen Hsieh et al.
Background: Omicron is known for its higher transmissibility and milder respiratory symptoms than those of other SARS-CoV-2 variants. How comorbidities contribute to mortality outcomes in Omicron-related COVID-19 remains ...
Emerging imipenem resistance in Nocardia infections in Taiwan: a retrospective cohort study at a tertiary teaching hospital [0.03%]
台湾一家三级教学医院内芽生菌感染中碳青霉烯类耐药性增加的回顾队列研究
Da-Wei Jhou,Chian-Ya Yang,Chong Kei Lao et al.
Da-Wei Jhou et al.
Background: Nocardia species are emerging pathogens of increasing significance, particularly in immunocompromised hosts. Due to diverse clinical manifestations and resistance patterns, accurate identification is critical....
Longitudinal surveillance of molecular epidemiology and antimicrobial resistance of carbapenem-resistant Acinetobacter baumannii in Thailand [0.03%]
泰国碳青霉烯类耐药鲍曼不动杆菌的分子流行病学和抗菌药物耐药性的纵向监测研究
Kamonwan Taesoongnern,Made Rai Dwitya Wiradiputra,Krit Thirapanmethee et al.
Kamonwan Taesoongnern et al.
Background: Carbapenem-resistant Acinetobacter baumannii (CRAB) is a major cause of healthcare-associated infections, especially in intensive care units. Its rapid acquisition of antimicrobial resistance necessitates mole...
Synergistic activity of mitomycin C in combination with ciprofloxacin against severe Vibrio vulnificus infection [0.03%]
丝裂霉素C与环丙沙星联合治疗严重威氏气单胞菌感染的协同作用
Cheng-Fa Yeh,Chi-Chung Chen,Chih-Cheng Lai et al.
Cheng-Fa Yeh et al.
Background: Vibrio vulnificus is a highly virulent pathogen associated with rapidly progressive sepsis and necrotising soft-tissue infection, particularly among patients with diabetes or chronic liver disease. Effective t...
Chien-Min Chu,Chih-Yu Huang,Chung-Chieh Yu et al.
Chien-Min Chu et al.
Background: Unusual cell death in immune cells contributes to immunosuppression in sepsis. Neutrophils play a crucial role in fighting pathogens. However, the roles of apoptosis, pyroptosis, and neutrophil extracellular t...