Extensive evolution analysis of the global chikungunya virus strains revealed the origination of CHIKV epidemics in Pakistan in 2016 [0.03%]
登革病毒2016年在巴基斯坦爆发的广泛进化分析及其起源追溯研究
Junming Shi,Zhengyuan Su,Zhaojun Fan et al.
Junming Shi et al.
Chikungunya virus (CHIKV) is a mosquito-borne virus that causes epidemics widely in the world especially in the tropical and subtropical regions. Phylogenetic analysis has found that the CHIKV lineages were associated with the spatial and t...
Wenxi An,Ningning Ge,Yilin Cao et al.
Wenxi An et al.
Chikungunya virus (CHIKV) is an arbovirus transmitted by Aedes mosquitos in tropical and subtropical regions across the world. After decades of sporadic outbreaks, it re-emerged in Africa, Asia, India Ocean and America suddenly, causing maj...
Developing a bacteriophage cocktail for biocontrol of potato bacterial wilt [0.03%]
用于生物防治马铃薯细菌性青枯病的噬菌体鸡尾酒制剂的研究与发展
Cuihua Wei,Junli Liu,Alice Nyambura Maina et al.
Cuihua Wei et al.
Bacterial wilt is a devastating disease of potato and can cause an 80% production loss. To control wilt using bacteriophage therapy, we isolated and characterized twelve lytic bacteriophages from different water sources in Kenya and China. ...
Crystal structure of the coxsackievirus A16 RNA-dependent RNA polymerase elongation complex reveals novel features in motif A dynamics [0.03%]
柯萨奇病毒A16依赖RNA的RNA聚合酶延伸复合物晶体结构揭示了动态变化的新特征
Peng Bi,Bo Shu,Peng Gong
Peng Bi
The RNA-dependent RNA polymerases (RdRPs) encoded by RNA viruses represent a unique class of nucleic acid polymerases. Unlike other classes of single-subunit polymerases, viral RdRPs have evolved a unique conformational change in their palm...
Ke Lan,Min-Hua Luo
Ke Lan
This special issue is dedicated to the recent research progress on human herpesviruses (HHVs). Human herpesviruses are distributed worldwide, and more than 90% of adults are infected by one or multiple HHVs. The HHV family contains three su...
Elevated expression of EBV and TLRs in the brain is associated with Rasmussen's encephalitis [0.03%]
Epstein-Barr病毒和TLRs在脑中的表达与Rasmussen脑炎有关
Xin Wang,Yisong Wang,Dong Liu et al.
Xin Wang et al.
Rasmussen's encephalitis (RE) is a rare pediatric neurological disorder, the etiology of which remains unclear. It has been speculated that the immunopathogenesis of RE involves damage to neurons, which eventually leads to the occurrence of...
Human cytomegalovirus miR-US5-1 inhibits viral replication by targeting Geminin mRNA [0.03%]
人巨细胞病毒的miR-US5-1通过靶向Geminin mRNA抑制病毒复制
Shujuan Jiang,Yujing Huang,Ying Qi et al.
Shujuan Jiang et al.
Viruses commonly create favorable cellular conditions for their survival through multiple mechanisms. MicroRNAs (miRNAs), which function as post-transcriptional regulators, are utilized by human cytomegalovirus (HCMV) in its infection and p...
Varicella-zoster virus ORF7 interacts with ORF53 and plays a role in its trans-Golgi network localization [0.03%]
水痘-带状疱疹病毒ORF7与ORF53相互作用并在其高尔基体网络定位中发挥作用
Wei Wang,Wenkun Fu,Dequan Pan et al.
Wei Wang et al.
Varicella-zoster virus (VZV) is a neurotropic alphaherpesvirus that causes chickenpox and shingles. ORF7 is an important virulence determinant of VZV in both human skin and nerve tissues, however, its specific function and involved molecula...
Prevalence of Kaposi's sarcoma-associated herpesvirus in Uygur and Han populations from the Urumqi and Kashgar regions of Xinjiang, China [0.03%]
新疆乌鲁木齐和喀什地区汉族人和维吾尔族人群KSHV感染的血清流行病学调查
Jun Zheng,Yang Yang,Meng Cui et al.
Jun Zheng et al.
Kaposi's sarcoma-associated herpesvirus (KSHV) is the infectious etiologic agent associated with Kaposi's sarcoma (KS), primary effusion lymphoma, and multicentric Castleman disease. It has been shown that high KSHV prevalence and high inci...
Detection of congenital cytomegalovirus in newborns using nucleic acid amplification techniques and its public health implications [0.03%]
应用核酸扩增技术检测新生儿先天性巨细胞病毒感染及其公共卫生意义
Guoyu Liu,Rong Hai,Fenyong Liu
Guoyu Liu
Human cytomegalovirus (HCMV), a herpesvirus, is an important human pathogen that causes asymptomatic infections in healthy or immunocompetent individuals but can lead to severe and potentially life-threatening complications in immune-immatu...