Puerarin Regulates Gut Homeostasis in T2DM Rats Involving Structural and Functional Alterations of Gut Microbiota and Paneth Cell Function [0.03%]
葛根素通过结构和功能重塑肠道菌群及潘氏细胞发挥T2DM大鼠肠道稳态调节作用
Yong-Zheng Wu,Lei Wang,Yao-Xiang Sun et al.
Yong-Zheng Wu et al.
Objective: To investigate the impact of puerarin on gut microbiota and epithelial integrity and glucose metabolism on a type 2 diabetes mellitus (T2DM) rat model. ...
Four Isosteroidal Alkaloids from Fritillaria Alleviate Lipopolysaccharide-Induced Inflammation in vitro and in vivo through MyD88- and TRIF-Dependent Signaling Pathways [0.03%]
四种异构体生物碱通过MyD88和TRIF依赖的信号途径缓解内毒素诱导的炎症作用
Er-Bu Aga,Ming-Xin Pai,Meng-Rui Zhang et al.
Er-Bu Aga et al.
Objective: To investigate the anti-inflammatory effects and mechanisms of action of 4 steroidal alkaloids (ebeiedinone, imperialine, chuanbeinone, and peimisine) in Fritillaria. ...
Honeysuckle-Derived Exosome-Like Nanovesicles Alleviate Cisplatin-Induced Acute Kidney Injury by Anti-Inflammation and Mitochondrial Function Protection [0.03%]
金银花衍生的类外泌体纳米囊泡通过抗炎和线粒体功能保护缓解顺铂引起的急性肾损伤
Wan-Cheng Gong,Jing-Xuan Li,Xiao-Juan Hu et al.
Wan-Cheng Gong et al.
Objective: To explore the potential of honeysuckle-derived exosome-like nanovesicles (HELNVs) for preventing cisplatin-induced acute kidney injury (AKI). ...
Risk Factors for Severity of Adverse Events Associated with Xuebijing Injection: A Propensity Score-Matched Analysis [0.03%]
雪靖注射液不良事件严重程度的风险因素：倾向分值匹配分析
Rui Zheng,Zhuo Chen,Xiao-Ying Zhong et al.
Rui Zheng et al.
Objective: To determine risk factors associated with the severity of Xuebijing Injection (XBJ)-related adverse events (AEs). Methods: T...
Prevention and Treatment of Doxorubicin and Trastuzumab-Induced Cardiotoxicity with Compound Danshen Dripping Pill [0.03%]
复方丹参滴丸防治多柔比星和赫赛汀致心肌毒性的临床研究
Nuo-Xian Yu,Meng-Meng Lin,Jing Xu et al.
Nuo-Xian Yu et al.
Objective: To elucidate the therapeutic effect and mechanism of Compound Danshen Dripping Pill (CDDP) on cardiotoxicity caused by doxorubicin (DOX) and trastuzumab (TRZ) METHODS: Eighteen Sprague-Dawley (SD) rats were ran...
Polysaccharide of Danggui Buxue Decoction Attenuates Colorectal Cancer via Modulating Intestinal Microflora and Metabolites [0.03%]
当归补血汤多糖通过调节肠道微生态及代谢物抑制结直肠癌的作用研究
Min Guo,Xin-Chi Zhang,Dong-Fei Guo et al.
Min Guo et al.
Objective: To explore whether polysaccharide of Danggui Buxue Decoction (formula polysaccharide, FP) could attenuate colorectal cancer (CRC) via modulating intestinal microflora and metabolites. ...
Tongxinluo Adjunctive Therapy and 12-Month Cardiovascular Outcomes after ST-Segment Elevation Myocardial Infarction: A Real-World Multicenter Prospective Cohort Study [0.03%]
通心络辅助治疗对ST段抬高型心肌梗死后12个月心血管结局的影响：一项真实世界多中心前瞻性队列研究
Guo-Qiang Yuan,Cheng-Cheng Chang,Li-Min Yang et al.
Guo-Qiang Yuan et al.
Objective: To evaluate the efficacy and safety of Tongxinluo in improving medium- and long-term prognosis of patients with ST-segment elevation myocardial infarction (STEMI) in a real-world setting. ...
Effect and Mechanism of Cerebrovasodilation Induced by Total Flavonoids of Chuzhou Chrysanthemum in Rats [0.03%]
滁菊总黄酮 cerebrovasodilative效应及机制研究
Xiao Wang,Miao Wu,Yu-Wen Li et al.
Xiao Wang et al.
Objective: To investigate cerebral vasorelaxation of total flavonoids of Chuzhou chrysanthemum (TFCC) in rats and its mechanism. Methods: ...
Anti-inflammatory and Anti-apoptotic Effects of Hypericum Japonicum and its Active Compounds in Hepatic Fibrosis [0.03%]
hypericum japonicum及其活性成分对肝纤维化的抗炎和抗凋亡作用
Yin-Jia He,Chang-Ming Yang,Xiao-Dong Liu et al.
Yin-Jia He et al.
Objective: To explore the therapeutic efficacy of Hypericum japonicum (HJ) and its active compounds in mitigating hepatic fibrosis by elucidating their anti-inflammatory and anti-apoptotic effects. ...
Isoquercitrin Improves Insulin Resistance by Inhibiting PTP1B-Regulated IRS/PI3K/AKT Signaling Pathway [0.03%]
异鼠李素通过抑制PTP1B调节的IRS / PI3K / AKT信号通路改善胰岛素抵抗
Si-Yu Liu,Lu-Jing Yu,Sheng-Nan Zhang et al.
Si-Yu Liu et al.
Objective: To explore the molecular mechanism by which protein tyrosine phosphatase 1B (PTP1B) enzyme regulates insulin resistance (IR) in diabetes mellitus, and the regulation of isoquercitrin (IS) on PTP1B in vitro and ...