Protective Effect of Arabinoxylan against Scopolamine-Induced Learning and Memory Impairment [0.03%]
阿拉伯木聚糖对胡椒碱致小鼠学习和记忆障碍的保护作用
Chang-Yul Kim,Gil-Yong Lee,Gyu Hwan Park et al.
Chang-Yul Kim et al.
The purpose of this study is to investigate the memory enhancing effect and underlying molecular mechanism of arabinoxylan (AX), a major component of dietary fiber in wheat against scopolamine (SCO)-induced amnesia in Sprague-Dawley (SD) ra...
Conditioned place preference and self-administration induced by nicotine in adolescent and adult rats [0.03%]
尼古丁在青春期和成年大鼠中引发的条件位置偏好及自我施用研究
Hafiz Muhammad Ahsan,June Bryan I de la Peña,Chrislean Jun Botanas et al.
Hafiz Muhammad Ahsan et al.
Nicotine addiction is a worldwide problem. However, previous studies characterizing the rewarding and reinforcing effects of nicotine in animal models have reported inconsistent findings. It was observed that the addictive effects are varia...
Strain differences in the chronic mild stress animal model of depression and anxiety in mice [0.03%]
慢性轻度压力抑郁和焦虑模型中不同品系小鼠的差异性研究
Yang-Hee Jung,Sa-Ik Hong,Shi-Xun Ma et al.
Yang-Hee Jung et al.
Chronic mild stress (CMS) has been reported to induce an anhedonic-like state in mice that resembles some of the symptoms of human depression. In the present study, we used a chronic mild stress animal model of depression and anxiety to exa...
Dioscorea Extract (DA-9801) Modulates Markers of Peripheral Neuropathy in Type 2 Diabetic db/db Mice [0.03%]
薯蓣提取物（DA-9801）调节db/db小鼠外周神经病的标志物
Eunjung Moon,Sung Ok Lee,Tong Ho Kang et al.
Eunjung Moon et al.
The purpose of this study was to investigate the therapeutic effects of DA-9801, an optimized extract of Dioscorea species, on diabetic peripheral neuropathy in a type 2 diabetic animal model. In this study, db/db mice were treated with DA-...
The Leaves of Broussonetia kazinoki Siebold Inhibit Atopic Dermatitis-Like Response on Mite Allergen-Treated Nc/Nga Mice [0.03%]
光叶银芽菊的叶子抑制尘螨过敏原处理的小鼠斑秃样反应
Hoyoung Lee,Hyekyung Ha,Jun Kyoung Lee et al.
Hoyoung Lee et al.
Broussonetia kazinoki Siebold. (B. kazinoki) has long been used in the manufacture of paper in Asian countries. Although B. kazinoki leaves (BK) have been employed in dermatological therapy, use of BK has not been tested in patients with at...
Resveratrol-Enriched Rice Down-Regulates Melanin Synthesis in UVB-Induced Guinea Pigs Epidermal Skin Tissue [0.03%]
富白藜芦醇大米下调UVB诱导的豚鼠表皮皮肤组织黑色素合成
Taek Hwan Lee,Jae Ok Seo,Moon Ho Do et al.
Taek Hwan Lee et al.
Synthetic compounds that are used in the clinic to regulate skin hyperpigmentation, such as arbutin, hydroquinone, and kojic acid, are only moderately effective. But, their use is limited by side effects. As part of an effort to overcome th...
Resveratrol Inhibits IL-6-Induced Transcriptional Activity of AR and STAT3 in Human Prostate Cancer LNCaP-FGC Cells [0.03%]
白藜芦醇通过抑制IL-6诱导的AR和STAT3转录活性而发挥抗前列腺癌作用
Mee-Hyun Lee,Joydeb Kumar Kundu,Young-Sam Keum et al.
Mee-Hyun Lee et al.
Prostate cancer is the most frequently diagnosed cancer. Although prostate tumors respond to androgen ablation therapy at an early stage, they often acquire the potential of androgen-independent growth. Elevated transcriptional activity of ...
Protective Effects of Chlorogenic Acid against Experimental Reflux Esophagitis in Rats [0.03%]
氯ogenic酸对实验性胃食管反流病的保护作用研究
Jung-Woo Kang,Sun-Mee Lee
Jung-Woo Kang
Esophageal reflux of gastric contents causes esophageal mucosal damage and inflammation. Recent studies show that oxygen-derived free radicals mediate mucosal damage in reflux esophagitis (RE). Chlorogenic acid (CGA), an ester of caffeic ac...
Comparison of the Effects of Matrix Metalloproteinase Inhibitors on TNF-α Release from Activated Microglia and TNF-α Converting Enzyme Activity [0.03%]
金属基质素蛋白酶抑制剂对活化小胶质细胞分泌tnf-α及tace活性的影响比较研究
Eun-Jung Lee,Pyong-Gon Moon,Moon-Chang Baek et al.
Eun-Jung Lee et al.
Matrix metalloproteinases (MMPs) are zinc-dependent endopeptidases that regulate cell-matrix composition and are also involved in processing various bioactive molecules such as cell-surface receptors, chemokines, and cytokines. Our group re...
Effects of atomoxetine on hyper-locomotive activity of the prenatally valproate-exposed rat offspring [0.03%]
左旋诺塔津对丙戊酸钠致胎鼠损伤子代高活动行为的影响研究
Chang Soon Choi,Minha Hong,Ki Chan Kim et al.
Chang Soon Choi et al.
A substantial proportion of patients with autism spectrum disorder (ASD) display hyperactivity as a comorbid symptom. Exposure to valproic acid (VPA) during pregnancy produces ASD-like core behavioral phenotypes as well as hyperactivity in ...