Ribes fasciculatum var. chinense Attenuated Allergic Inflammation In Vivo and In Vitro [0.03%]
刺五加悬钩子减轻过敏反应炎症的能力
Ji-Wook Jung,Su-Jin Kim,Eun-Mi Ahn et al.
Ji-Wook Jung et al.
Ribes fasciculatum var. chinense MAX. (R. fasciculatum) has traditionally been used in Korea to treat inflammatory diseases. However, the exact mechanism that accounts for the anti-inflammatory effect of R. fasciculatum is not completely un...
Novel Suppressive Effects of Ketotifen on Migration and Invasion of MDA-MB-231 and HT-1080 Cancer Cells [0.03%]
克洛替丁对MDA-MB-231和HT-1080癌细胞迁移和侵袭的抑制作用
Hyun Ji Kim,Mi Kyung Park,Soo Youl Kim et al.
Hyun Ji Kim et al.
The high mortality rates associated with cancer reflect the metastatic spread of tumor cells from the site of their origin. Metastasis, in fact, is the cause of 90% of cancer deaths. Therefore, considerable effort is being made to inhibit m...
The Protective Effects of IGF-1 on Different Subpopulations of DRG Neurons with Neurotoxicity Induced by gp120 and Dideoxycytidine In Vitro [0.03%]
IGF-1对gp120和-ddC体外诱导的背根节神经元不同亚群保护作用的影响
Lin Lu,Haixia Dong,Guixiang Liu et al.
Lin Lu et al.
Peripheral neuropathy induced by human immunodeficiency virus (HIV) infection and antiretroviral therapy is not only difficult to distinguish in clinical practice, but also difficult to relieve the pain symptoms by analgesics because of the...
Apigenin Inhibits Tumor Necrosis Factor-α-Induced Production and Gene Expression of Mucin through Regulating Nuclear Factor-Kappa B Signaling Pathway in Airway Epithelial Cells [0.03%]
染料木素通过调节核因子-κB信号途径抑制肿瘤坏死因子-α诱导的气道上皮细胞黏蛋白的产生及基因表达
Hyo-Seok Seo,Mohamed Asaduzzaman Sikder,Hyun Jae Lee et al.
Hyo-Seok Seo et al.
In the present study, we investigated whether apigenin significantly affects tumor necrosis factor-α (TNF-α)-induced production and gene expression of MUC5AC mucin in airway epithelial cells. Confluent NCI-H292 cells were pretreated with ...
Role of annexin a5 on mitochondria-dependent apoptosis induced by tetramethoxystilbene in human breast cancer cells [0.03%]
四甲氧基茋诱导的人乳腺癌细胞线粒体依赖性凋亡中Annexin A5的作用研究
Mihye Hong,Nahee Park,Young-Jin Chun
Mihye Hong
We have previously shown that 2,4,3',5'-tetramethoxystilbene (TMS), a trans-stilbene analogue, induces apoptosis in human cancer cells. However, the detailed mechanisms of mitochondria-dependent apoptosis induced by TMS are not fully unders...
Arsenite Acutely Decreases Nitric Oxide Production via the ROS-Protein Phosphatase 1-Endothelial Nitric Oxide Synthase-Thr(497) Signaling Cascade [0.03%]
亚砷酸通过ROS-蛋白磷酸酶1-内皮型一氧化氮合酶-Thr(497)信号级联急性降低一氧化氮的产生
Jungwon Seo,Jee Young Lee,Min-Sun Sung et al.
Jungwon Seo et al.
Chronic (>24 h) exposure of arsenite, an environmental toxicant, has shown the decreased nitric oxide (NO) production in endothelial cells (EC) by decreasing endothelial NO synthase (eNOS) expression and/or its phosphorylation at serine 117...
Paraquat Induces Apoptosis through Cytochrome C Release and ERK Activation [0.03%]
百草枯通过细胞色素C释放和ERK活化诱导凋亡
Hong Joo Seo,Sang Joon Choi,Jung-Hee Lee
Hong Joo Seo
Paraquat has been suggested to induce apoptosis by generation of reactive oxygen species (ROS). However, little is known about the mechanism of paraquat-induced apoptosis. Here, we demonstrate that extracellular signal-regulated protein kin...
Arctigenin Increases Hemeoxygenase-1 Gene Expression by Modulating PI3K/AKT Signaling Pathway in Rat Primary Astrocytes [0.03%]
大黄素增加PI3K / AKT信号通路在原代大鼠少突胶质细胞前体中的HO-1基因表达
Yeon-Hui Jeong,Jin-Sun Park,Dong-Hyun Kim et al.
Yeon-Hui Jeong et al.
In the present study, we found that the natural compound arctigenin inhibited hydrogen peroxide-induced reactive oxygen species (ROS) production in rat primary astrocytes. Since hemeoxygenase-1 (HO-1) plays a critical role as an antioxidant...
Lightening up Light Therapy: Activation of Retrograde Signaling Pathway by Photobiomodulation [0.03%]
光生物调节通过光疗激活逆行信号通路
Hong Pyo Kim
Hong Pyo Kim
Photobiomodulation utilizes monochromatic (or quasimonochromatic) light in the electromagnetic region of 600∼1000 nm for the treatment of soft tissues in a nondestructive and nonthermal mode. It is conceivable that photobiomodulation is ba...
Non-thermal atmospheric-pressure plasma possible application in wound healing [0.03%]
非热等离子体在伤口愈合中的潜在应用
Beate Haertel,Thomas von Woedtke,Klaus-Dieter Weltmann et al.
Beate Haertel et al.
Non-thermal atmospheric-pressure plasma, also named cold plasma, is defined as a partly ionized gas. Therefore, it cannot be equated with plasma from blood; it is not biological in nature. Non-thermal atmospheric-pressure plasma is a new in...