Aerobic Exercise Ameliorates Muscle Atrophy Induced by Methylglyoxal via Increasing Gastrocnemius and Extensor Digitorum Longus Muscle Sensitivity [0.03%]
有氧运动通过增加比目鱼肌和趾长伸肌敏感性来改善甲基糖醛诱导的肌肉萎缩
Seong-Min Hong,Eun Yoo Lee,Jinho Park et al.
Seong-Min Hong et al.
Muscle atrophy is characterized by the loss of muscle function. Many efforts are being made to prevent muscle atrophy, and exercise is an important alternative. Methylglyoxal is a well-known causative agent of metabolic diseases and diabeti...
Eun-Sook Kim,Sun Young Kim,Aree Moon
Eun-Sook Kim
Many cancers arise from sites of chronic inflammation, which creates an inflammatory microenvironment surrounding the tumor. Inflammatory substances secreted by cells in the inflammatory environment can induce the proliferation and survival...
Keun Soo Ahn,Koo Jeong Kang,Yong Hoon Kim et al.
Keun Soo Ahn et al.
Bile pigment, bilirubin, and biliverdin concentrations may change as a results of biliary tract cancer (BTC) altering the mechanisms of radical oxidation and heme breakdown. We explored whether changes in bile pigment components could help ...
A Novel Role of Hyaluronic Acid and Proteoglycan Link Protein 1 (HAPLN1) in Delaying Vascular Endothelial Cell Senescence [0.03%]
透明质酸和蛋白聚糖链接蛋白1(HAPLN1)在延缓血管内皮细胞衰老中的新作用
Dan Zhou,Ji Min Jang,Goowon Yang et al.
Dan Zhou et al.
Cardiovascular diseases (CVDs) are the most common cardiovascular system disorders. Cellular senescence is a key mechanism associated with dysfunction of aged vascular endothelium. Hyaluronic acid and proteoglycan link protein 1 (HAPLN1) ha...
Novel Effect of Hyaluronan and Proteoglycan Link Protein 1 (HAPLN1) on Hair Follicle Cells Proliferation and Hair Growth [0.03%]
透明质酸和蛋白聚糖链接蛋白1(HAPLN1)对毛囊细胞增殖及生发的新作用
Hae Chan Ha,Dan Zhou,Zhicheng Fu et al.
Hae Chan Ha et al.
Hair loss is a common condition that can have a negative impact on an individual's quality of life. The severe side effects and the low efficacy of current hair loss medications create unmet needs in the field of hair loss treatment. Hyalur...
Inhaled Volatile Molecules-Responsive TRP Channels as Non-Olfactory Receptors [0.03%]
气道上皮中的TRP通道非嗅觉感知挥发性化学分子的受体
Hyungsup Kim,Minwoo Kim,Yongwoo Jang
Hyungsup Kim
Generally, odorant molecules are detected by olfactory receptors, which are specialized chemoreceptors expressed in olfactory neurons. Besides odorant molecules, certain volatile molecules can be inhaled through the respiratory tract, often...
The Effect of γ-Aminobutyric Acid Intake on UVB- Induced Skin Damage in Hairless Mice [0.03%]
γ-氨基丁酸干预对无毛小鼠紫外线损伤皮肤的影响研究
Hairu Zhao,Bomi Park,Min-Jung Kim et al.
Hairu Zhao et al.
The skin, the largest organ in the body, undergoes age-related changes influenced by both intrinsic and extrinsic factors. The primary external factor is photoaging which causes hyperpigmentation, uneven skin surface, deep wrinkles, and mar...
Association between LEPR Genotype and Gut Microbiome in Healthy Non-Obese Korean Adults [0.03%]
LEPR基因型与健康非肥胖韩国成人肠道微生物组的关系
Yoon Jung Cha,In Ae Chang,Eun-Heui Jin et al.
Yoon Jung Cha et al.
The LEPR (leptin receptor) genotype is associated with obesity. Gut microbiome composition differs between obese and non-obese adults. However, the impact of LEPR genotype on gut microbiome composition in humans has not yet been studied. In...
Biased Dopamine D2 Receptors Exhibit Distinct Intracellular Trafficking Properties and ERK Activation in Different Subcellular Domains [0.03%]
偏向的多巴胺D2受体在不同亚细胞区室表现出不同的胞内运输性质和ERK激活作用
Shujie Wang,Lulu Peng,Kyeong-Man Kim
Shujie Wang
Biased signaling or functional selectivity refers to the ability of an agonist or receptor to selectively activate a subset of transducers such as G protein and arrestin in the case of G protein-coupled receptors (GPCRs). Although signaling...
Intermittent Fasting Modulates Immune Response by Generating Tregs via TGF-β Dependent Mechanisms in Obese Mice with Allergic Contact Dermatitis [0.03%]
间歇性禁食通过肥胖小鼠中的过敏性接触性皮炎的TGF-β依赖机制生成Treg来调节免疫反应
Sang-Chul Han,Jung-Il Kang,Youn Kyung Choi et al.
Sang-Chul Han et al.
People with obesity maintain low levels of inflammation; therefore, their exposure to foreign antigens can trigger an excessive immune response. In people with obesity or allergic contact dermatitis (ACD), symptoms are exacerbated by a redu...