Analysis of SARS-CoV-2 Mutations after Nirmatrelvir Treatment in a Lung Cancer Xenograft Mouse Model [0.03%]
纳莫特雷韦治疗后小细胞肺癌异种移植小鼠模型中SARS-CoV-2的突变分析研究
Bo Min Kang,Dongbum Kim,Jinsoo Kim et al.
Bo Min Kang et al.
Paxlovid is the first approved oral treatment for coronavirus disease 2019 and includes nirmatrelvir, a protease inhibitor targeting the main protease (Mpro) of SARS-CoV-2, as one of the key components. While some specific mutations emerged...
Elafibranor PPARα/δ Dual Agonist Ameliorates Ovalbumin-Induced Allergic Asthma [0.03%]
PPARα/δ双激动剂Elafibranor改善卵清蛋白诱导的过敏性哮喘
Ye-Eul Lee,Dong-Soon Im
Ye-Eul Lee
Asthma is characterized by chronic inflammation and respiratory tract remodeling. Peroxisome proliferator-activated receptors (PPARs) play important roles in the pathogenesis and regulation of chronic inflammatory processes in asthma. The r...
Extracellular Vesicles Derived from Adipose Stem Cells Alleviate Systemic Sclerosis by Inhibiting TGF-β Pathway [0.03%]
外泌体通过抑制TGF-β途径治疗系统性硬化症
Eunae Kim,Hark Kyun Kim,Jae Hoon Sul et al.
Eunae Kim et al.
Systemic sclerosis is an autoimmune disease characterized by inflammatory reactions and fibrosis. Myofibroblasts are considered therapeutic targets for preventing and reversing the pathogenesis of fibrosis in systemic sclerosis. Although th...
Erratum to "Bispecific Antibody-Bound T Cells as a Novel Anticancer Immunotherapy" [Biomol. Ther. 30 (2022) 418-426] [0.03%]
“双特异性抗体结合T细胞作为一种新型的癌症免疫疗法”一文中表位二聚体的结构式有误
Jaewon Cho,Nara Tae,Jae-Hee Ahn et al.
Jaewon Cho et al.
Published Erratum
Biomolecules & therapeutics. 2024 May 1;32(3):400-401. DOI:10.4062/biomolther.2024.003 2024
Erratum to "Potential Role of Dietary Salmon Nasal Cartilage Proteoglycan on UVB-Induced Photoaged Skin" [Biomol. Ther. 32 (2024) 249-260] [0.03%]
“饮食鲑鱼鼻软骨蛋白多糖对UVB引起的光老化皮肤的潜在作用”一文的勘误注释[Biomol. Ther. 32 (2024) 249-260]
Hae Ran Lee,Seong-Min Hong,Kyohee Cho et al.
Hae Ran Lee et al.
Published Erratum
Biomolecules & therapeutics. 2024 May 1;32(3):399. DOI:10.4062/biomolther.2024.004 2024
Anti-Melanogenic Activity of Undecylprodigiosin, a Red Pigment Isolated from a Marine Streptomyces sp. SNA-077 [0.03%]
由海洋链霉菌(SNA-077)分离的抑黑素红色色素 undecylprodigiosin 的抗黑色素增生活性研究
Chaeyoung Lee,Jung Min Park,Prima F Hillman et al.
Chaeyoung Lee et al.
Bioassay and HPLC-UV guided fractionations of the crude extract of marine-derived Streptomyces sp. SNA-077 have led to the isolation of a red pigment, undecylprodigiosin (1). The chemical structure of undecylprodigiosin (1) was revealed by ...
Lysophosphatidic Acid Receptor 1 Plays a Pathogenic Role in Permanent Brain Ischemic Stroke by Modulating Neuroinflammatory Responses [0.03%]
溶血磷脂酸受体1通过调节神经炎症反应在永久性脑缺血性卒中发病机制中起作用
Supriya Tiwari,Nikita Basnet,Ji Woong Choi
Supriya Tiwari
Lysophosphatidic acid receptor 1 (LPA1) plays a critical role in brain injury following a transient brain ischemic stroke. However, its role in permanent brain ischemic stroke remains unknown. To address this, we investigated whether LPA1 c...
Morroniside Protects C2C12 Myoblasts from Oxidative Damage Caused by ROS-Mediated Mitochondrial Damage and Induction of Endoplasmic Reticulum Stress [0.03%]
Morroniside保护ROS介导的线粒体损伤和内质网应激诱导的氧化应激所致C2C12肌管细胞损伤
Hyun Hwangbo,Cheol Park,EunJin Bang et al.
Hyun Hwangbo et al.
Oxidative stress contributes to the onset of chronic diseases in various organs, including muscles. Morroniside, a type of iridoid glycoside contained in Cornus officinalis, is reported to have advantages as a natural compound that prevents...
Dae Ui Lee,Beom Seok Han,Kyung Hee Jung et al.
Dae Ui Lee et al.
Pancreatic ductal adenocarcinoma (PDAC) has a poor prognosis owing to its desmoplastic stroma. Therefore, therapeutic strategies targeting this tumor stroma should be developed. In this study, we describe the heterogeneity of cancer-associa...
Effect of Kaempferol on Modulation of Vascular Contractility Mainly through PKC and CPI-17 Inactivation [0.03%]
kaempferol通过PKC和CPI-17失活主要调节血管张力的作用
Hyuk-Jun Yoon,Heui Woong Moon,Young Sil Min et al.
Hyuk-Jun Yoon et al.
In this study, we investigated the efficacy of kaempferol (a flavonoid found in plants and plant-derived foods such as kale, beans, tea, spinach and broccoli) on vascular contractibility and aimed to clarify the detailed mechanism underlyin...