Albiflorin, a Monoterpene Glycoside, Protects Myoblasts against Hydrogen Peroxide-Induced Apoptosis by Activating the Nrf2/ HO-1 Axis [0.03%]
茋苷白皮素通过激活Nrf2/HO-1轴保护氢氧化钠诱导的肌细胞凋亡
Cheol Park,Hee-Jae Cha,Dong-Gu Kim et al.
Cheol Park et al.
Albiflorin, a key active compound in the roots of Paeonia lactiflora Pall, is known to have multiple health benefits. Although albiflorin has been shown to exert its major pharmacological effects via its antioxidant activity, its efficacy i...
Dimethyl Sulfoxide Shifts Human Mesenchymal Stem Cell Differentiation toward Adipogenesis over Osteogenesis [0.03%]
dimethyl sulfoxide使人类间充质干细胞分化为脂肪细胞而非成骨细胞
Seokyoung Hwang,Sungjin Ahn,Seungchan An et al.
Seokyoung Hwang et al.
Dimethyl sulfoxide (DMSO) is extensively used as a solvent in bioactive compound screening due to its capacity to solubilize a wide range of chemical compounds. This study demonstrates that DMSO significantly influences lineage commitment i...
BRL-50481 Ameliorates Lung Inflammation in a Murine Model of Ovalbumin-Induced Allergic Asthma with Co-Exposure to Lipopolysaccharide [0.03%]
巴夫霉素BRL-50481可减轻脂多糖联合作用于卵清蛋白致敏的小鼠模型中引起的哮喘肺部炎症作用
Oh Seong Kwon,Kyu-Taek Hwang,Won Seok Choi et al.
Oh Seong Kwon et al.
Asthma is an allergic inflammatory disease of the lungs characterized by eosinophilic inflammation, mucus hypersecretion, and airway hyperresponsiveness (AHR). Exposure to environmental endotoxins, such as lipopolysaccharide (LPS), can exac...
Erratum to "Morroniside Protects C2C12 Myoblasts from Oxidative Damage Caused by ROS-mediated Mitochondrial Damage and Induction of Endoplasmic Reticulum Stress" [Biomol Ther 32(3), 349-360 (2024)] [0.03%]
关于“Morroniside保护C2C12肌管细胞免受ROS介导的线粒体损伤和内质网应激诱导的氧化损伤”一文的勘误[Biomol Ther 32(3), 349-360 (2024)]
Hyun Hwangbo,Cheol Park,EunJin Bang et al.
Hyun Hwangbo et al.
Erratum to "Suppression of Lipopolysaccharide-induced Inflammatory and Oxidative Response by 5-Aminolevulinic Acid in RAW 264.7 Macrophages and Zebrafish Larvae" [Biomol Ther 29(6), 685-696 (2021)] [0.03%]
《5氨基乙醛酸通过RAW 264.7巨噬细胞和斑马鱼幼体抑制脂多糖诱导的炎症和氧化反应》的勘误[生物分子治疗,29(6), 685-696 (2021)]
Seon Yeong Ji,Hee-Jae Cha,Ilandarage Menu Neelaka Molagoda et al.
Seon Yeong Ji et al.
Hederacoside C Modulates EGF-Induced MUC5AC Mucin Gene Expression by Regulating the MAPK Signaling Pathway in Human Airway Epithelial Cells [0.03%]
Hedgecoside C通过调节MAPK信号途径调控人呼吸道上皮细胞中EGF诱导的MUC5AC黏蛋白基因表达
Rajib Hossain,Md Solayman Hossain,Hyun Jae Lee et al.
Rajib Hossain et al.
This study aimed to evaluate the potential of hederacoside C, an active compound isolated from Hedera helix, which has been used for managing inflammatory respiratory diseases, in attenuating epidermal growth factor (EGF)-induced airway MUC...
Anti-Inflammatory Activity of Cell-Penetrating Peptide Nucleic Acids Targeting Indoleamine 2,3-Dioxygenase 1 in IFNγ-Treated Human Keratinocytes [0.03%]
细胞穿透肽核酸通过抑制干扰素诱导的IDO1表达发挥抗炎作用
Daram Jung,Sungjin Ahn,In Guk Park et al.
Daram Jung et al.
Indoleamine 2,3-dioxygenase 1 (IDO1) is an enzyme that plays a pivotal role in immune regulation by metabolizing tryptophan into kynurenine, leading to T cell suppression and promoting immune tolerance. However, persistent activation of IDO...
Inhibition of Sphingosine-1-Phosphate Receptor 2 (S1P2) Attenuates Imiquimod-Induced Psoriasis-Like Skin Inflammation in BALB/c Mice [0.03%]
鞘氨醇-1-磷酸受体2(S1P2)抑制剂可减轻BALB/c小鼠咪喹莫德诱导的银屑病样皮肤炎症
Ju-Hyun Lee,Dong-Soon Im
Ju-Hyun Lee
Serum and epidermal levels of sphingosine 1-phosphate (S1P) are higher in patients with psoriasis than healthy subjects. Although roles of type 1 S1P receptor, S1P1, in the development of psoriasis has intensively been investigated, roles o...
Paeoniflorin Protects Retinal Pigment Epithelial Cells from High Glucose-Induced Oxidative Damage by Activating Nrf2-Mediated HO-1 Signaling [0.03%]
芍药苷通过激活Nrf2介导的HO-1信号保护视网膜色素上皮细胞免受高糖诱导的氧化损伤
Cheol Park,Hee-Jae Cha,Su Hyun Hong et al.
Cheol Park et al.
Oxidative stress due to hyperglycemia damages the functions of retinal pigment epithelial (RPE) cells and is a major risk factor for diabetic retinopathy (DR). Paeoniflorin is a monoterpenoid glycoside found in the roots of Paeonia lactiflo...
MLKL Inhibitor Reduces Oxidative Stress, Inflammation, and Dopaminergic Neuronal Cell Death in MPTP-Induced Parkinson's Disease Mouse Model [0.03%]
MLKL抑制剂可减少帕金森病模型小鼠中的氧化应激、炎症及多巴胺能神经元死亡
Do-Yeon Kim,Yea-Hyun Leem,Hee-Sun Kim
Do-Yeon Kim
Parkinson's disease (PD) is a movement disorder characterized by the progressive loss of dopaminergic neurons in the substantia nigra (SN). Recent studies have shown that necroptosis is involved in the development of inflammatory and neurod...