Cloning and Expression in Pichia pastoris of a New Cytochrome P450 Gene from a Dandruff-causing Malassezia globosa [0.03%]
来自引起头屑的球形马拉色菌的新细胞色素P450基因的克隆和毕赤酵母表达
Eun Chang Lee,Seul Ong Ohk,Bo Young Suh et al.
Eun Chang Lee et al.
The Malassezia fungi are responsible for various human skin disorders including dandruff and seborrheic dermatitis. Of the Malassezia fungi, Malassezia globosa (M. globosa) is one of the most common in human scalp. The completed genome sequ...
Methanolic Extract of Asterina pectinifera inhibits LPS-Induced Inflammatory Mediators in Murine Macrophage [0.03%]
Asterina pectinifera 甲醇提取物通过抑制小鼠巨噬细胞中LPS诱导的炎症介质发挥作用
Wol-Soon Jo,Yoo Jin Choi,Hyoun Ji Kim et al.
Wol-Soon Jo et al.
This study aimed to elucidate anti-inflammatory activities from extracts of Asterina pectinifera on nitric oxide (NO) production, TNF-α and IL-6 release in lipopolysaccharide (LPS) -stimulated murine macrophage cell, RAW264.7. We prepared ...
Antimutagenic and Anticarcinogenic Effect of Methanol Extracts of Sweetpotato (Ipomea batata) Leaves [0.03%]
甘藷叶甲醇萃取物之反致突变及防癌效果
Hwan-Goo Kang,Sang-Hee Jeong,Joon-Hyoung Cho
Hwan-Goo Kang
The present study was conducted to investigate the antimutagenic potential of the methanolic extract from the leaves of sweet potato (Ipomea batatas, IB) with the SOS chromotest (umu test) and Salmonella typhimurium TA 98 and TA 100. The an...
Gene expression analysis of so called asian dust extracts in human acute myeloid leukemia cells [0.03%]
人急性髓系白血病细胞中所谓亚洲沙尘提取物的基因表达分析
You-Jin Choi,Hu-Quan Yin,Eun-Jung Park et al.
You-Jin Choi et al.
As the frequency and the intensity of so called Asian dust (AD) events have increased, public concerns about the adverse health effects has spiked sharply over the last two decades. Despite the recent reports on the correlation between AD e...
Identification of differentially expressed genes in human mesenchymal stem cell-derived neurons [0.03%]
人间充质干细胞来源神经元差异基因的鉴定
Ji Hye Heo,Kyung Jin Cho,Dal Woong Choi et al.
Ji Hye Heo et al.
Mesenchymal stem cells (MSCs) have greater potential for immediate clinical and toxicological applications, due to their ability to self-renew, proliferate, and differentiate into a variety of cell types. To identify novel candidate genes t...
Assessment of the dermal and ocular irritation potential of lomefloxacin by using in vitro methods [0.03%]
体外方法评估洛美沙星的皮肤和眼睛刺激潜能
Jun-Ho Ahn,Ki-Hwan Eum,Michael Lee
Jun-Ho Ahn
The evaluation of eye and skin irritation potential is essential to ensuring the safety of human in contact with a wide variety of substances. Despite this importance of irritation test, little is known with respect to the irritation potenc...
Applications of genetically modified tools to safety assessment in drug development [0.03%]
基因工程工具在药物开发安全性评价中的应用
Hee Yeon Kay,Hongmin Wu,Seo In Lee et al.
Hee Yeon Kay et al.
The process of new drug development consists of several stages; after identifying potential candidate compounds, preclinical studies using animal models link the laboratory and human clinical trials. Among many steps in preclinical studies,...