Single and repeated-dose toxicity studies by intravaginal administration of Lactobacillus plantarum ATG-K2 powder in female rats [0.03%]
植物乳杆菌ATG-K2粉剂单次及反复灌阴对雌性大鼠毒理学研究
Jae-Hyun Kang,Min-Soo Kang,Sun-Don Kim et al.
Jae-Hyun Kang et al.
Bacterial vaginosis (BV) is a microbial dysbiosis that shifts the paradigms of vaginal flora from lactobacilli to opportunistic pathogens. Globally, BV is treated with antibiotic therapy and recurrence rates are > 70% occurring within 6 mon...
Exploring the various functions of PHD finger protein 20: beyond the unknown [0.03%]
探索PHD指环蛋白20的多种功能：超出未知领域
Uijin Juang,Suhwan Gwon,Woohyeong Jung et al.
Uijin Juang et al.
Over the last decade, the functions of PHD finger protein 20 (PHF20) in several signaling processes have been studied, including those of protein kinase B (PKB)-mediated phosphorylation, p53 regulation, muscle differentiation, and histone m...
Evaluation of acute, repeated dose 28-day and 13-week oral toxicity and genotoxicity of a standardized fraction (HemoHIM) from Angelica gigas, Cnidium officinale, and Paeonia lactiflora [0.03%]
当归、蛇床子和白芍标准化组方（HemoHIM）的急性毒性、28天多次口服给药毒性、13周经口毒性及致基因突变性评价
Ju Gyeong Kim,Su-Bin Bak,Gyoung-Deuck Kim et al.
Ju Gyeong Kim et al.
HemoHIM is a functional food ingredient comprising a triple herbal combination of extracts from Angelica gigas Nakai, Cnidium officinale Makino, and Paeonia lactiflora Pallas. It was developed to aid the recovery of impaired immune function...
Uijin Juang,Soohyeon Lee,Suhwan Gwon et al.
Uijin Juang et al.
Plant homeodomain finger protein 20 (PHF20) plays a crucial role in various biological processes, but its involvement in renal fibrosis remains unclear. This study investigated the role of PHF20 in renal fibrosis using a unilateral ureteral...
Rocaglamide-A mitigates LPS-induced hepatic inflammation by modulating JNK/AP-1 signaling cascade and ROS production in hepatocytes [0.03%]
罗库拉明A通过调节JNK/AP-1信号级联和肝细胞ROS产生缓解LPS诱导的肝脏炎症
Yoon-Su Ha,Taek-Kyong Kim,Jun Heo et al.
Yoon-Su Ha et al.
Lipopolysaccharide (LPS), a gut-derived endotoxin, is a recognized risk factor for both Non-alcoholic fatty liver disease (NAFLD) and alcoholic liver disease (ALD). Rocaglamide-A (Roc-A), a natural compound derived from the genus Aglaia, is...
Quinine inhibits myogenic differentiation by disrupting AKT signaling pathway [0.03%]
奎宁通过破坏AKT信号通路抑制肌源性分化
Mi Ran Byun,Sou Hyun Kim,RanJu Woo et al.
Mi Ran Byun et al.
Sarcopenia is a disease characterized by decreased muscle fibers and mass. Although it mainly affects the older adults, it can also occur in various age groups as a secondary effect of medications used for treating certain diseases, such as...
Oral toxicity and genotoxicity assessment of standardized Echinacea purpurea (L.) extract and the pharmacokinetic profile of its active ingredient chicoric acid [0.03%]
紫锥菊口服毒理及遗传毒性评估和其有效成分木犀草素的药代动力学研究
Ji-Soo Jeong,Jeong-Won Kim,Jin-Hwa Kim et al.
Ji-Soo Jeong et al.
Echinacea purpurea (L.), a member of Asteraceae family, has traditionally been used in numerous countries to treat and prevent various immune-related diseases. This study confirmed the oral toxicity and genotoxicity profile of standardized ...
Neuroprotective effects of cerebroprotein hydrolysate and its combination with antioxidants against oxidative stress-induced HT22 cell death [0.03%]
脑蛋白水解物及其与抗氧化剂联合对抗氧化应激诱导的HT22细胞死亡的神经保护作用
Eun-Ju Yang,Jae Cheon Kim,Dong Hee Na
Eun-Ju Yang
This study aimed to investigate the neuroprotective effects of cerebroprotein hydrolysate (CPH) against oxidative stress-induced HT22 cell death. Additionally, the effect of antioxidants such as quercetin (QC) and N-acetyl-L-cysteine (NAC) ...
Identification of acrolein as a novel diagnostic odor biomarker for 1,2,3-trichloropropane-induced hepatotoxicity in Sprague Dawley rats [0.03%]
1,2,3-三氯丙烷致大鼠肝损伤的新型诊断气味生物标志物——丙烯醛的识别
Ji Eun Kim,Tae Ryeol Kim,Hee Jin Song et al.
Ji Eun Kim et al.
Body odor is considered a diagnostic indicator of various infectious and chronic diseases. But, few studies have examined the odor markers for various toxic effects in the mammalian system. This study attempted to identify the novel diagnos...
Retraction Note: Flavonoid fractions of diosmin and hesperidin mitigate lead acetate-induced biochemical, oxidative stress, and histopathological alterations in Wistar rats [0.03%]
撤回 notice: 二氢杨梅素和橙皮苷减轻醋酸铅诱导的 wistar 大鼠生化、氧化应激及组织病理变化
Ibrahim Yusuf Lamidi,Hudu Garba Mikail,Sani Adamu et al.
Ibrahim Yusuf Lamidi et al.
[This retracts the article DOI: 10.1007/s43188-020-00084-9.]. © Korean Society of Toxicology 2024.
Retraction of Publication
Toxicological research. 2024 Jul 30;40(4):701. DOI:10.1007/s43188-024-00257-w 2024