Bisphenol A and reproductive health: a comprehensive overview of toxicological effect [0.03%]
双酚A与生殖健康：毒理学效应综述
Adfar Reyaz,Darakhshan Javaid,Syed Sanober Qadri et al.
Adfar Reyaz et al.
Bisphenol A (BPA), a synthetic compound extensively used in the production of polycarbonate plastics and epoxy resins, is a pervasive environmental contaminant and a potent endocrine disruptor. By mimicking oestrogen and binding to oestroge...
Unveiling the intriguing potential of Bacopa monnieri extract in alleviating cypermethrin-induced hypothyroidism and oxidative stress in female mice [0.03%]
巴基奥神草提取物在缓解女性小鼠丙氰聚醚诱导的甲状腺功能减退和氧化应激中的潜在作用探究
Surbhi Chourasiya,Anand Kar,Versha Sharma
Surbhi Chourasiya
Cypermethrin (CYP) is a commonly used type II Pyrethroid pesticide, that normally accumulates in the various body tissues, causing organ dysfunction. In order to reduce its toxicity, we primarily investigated the potential of Bacopa monnier...
Mechanism of endoplasmic reticulum stress-induced endothelial cell ferroptosis in trichloroethylene-induced mouse kidney injury [0.03%]
三氯乙烯致小鼠肾脏损伤的内质网应激介导的内皮细胞铁死亡机制
Meng Huang,Jiaxiang Zhang,Rui Li et al.
Meng Huang et al.
Trichloroethylene (TCE) is widely employed as a cleaning agent in industrial settings. Occupational exposure to TCE can lead to occupational medicamentose-like dermatitis due to trichloroethylene (OMDT). Our previous research has identified...
Case study on the evaluation of skin sensitization for 23 selected fragrance ingredients using a defined approach based on OECD Guideline 497 [0.03%]
基于OECD指南497的皮肤致敏评价方法对23种香料进行评估的案例研究
Hyejin Kim,Kwangsik Park
Hyejin Kim
Twenty-three single-ingredient substances, selected from materials labeled as allergens in cosmetic fragrances, were assessed for skin sensitization potential using a defined approach (DA) based on the OECD Guideline 497 Integrated Testing ...
Oxidative stress and pancreatic cancer: a dual role in tumorigenesis and drug toxicity [0.03%]
氧化应激与胰腺癌：在肿瘤发生和药物毒性的双重作用
Khem Raj Limbu,Rashmi Bhandari Chhetri,Yoon Sin Oh et al.
Khem Raj Limbu et al.
Pancreatic ductal adenocarcinoma (PDAC) is an aggressive and treatment-resistant malignancy with a poor prognosis. Among the multifactorial mechanisms implicated in the progression of PDAC, oxidative stress, defined as an imbalance between ...
Chitooligosaccharides as a potential immune modulator for reducing particulate matter 10-induced inflammation in pulmonary damage models [0.03%]
壳寡糖作为潜在免疫调节剂用于减少肺损伤模型中颗粒物引起的炎症
Chan-Ho Park,Yun-Ho Kim,Ju Myung Kim et al.
Chan-Ho Park et al.
This study investigated the effects of chitooligosaccharides (COS) on proinflammatory cytokines and nuclear factor-κB (NF-κB) activation in particulate matter 10 (PM10)-induced mice. Results demonstrated that COS treatment significantly r...
Pre and postnatal exposure to glyphosate-based herbicides and potential neurodevelopmental outcomes: a systematic review of animal and epidemiological studies [0.03%]
除草剂葡甘露聚糖孕前、孕期及出生后的暴露与潜在的神经发育结局：动物和流行病学研究的系统评价
Nathália Ribeiro Dos Santos,Homegnon Antonin Ferréol Bah,Erival Amorim Gomes-Júnior et al.
Nathália Ribeiro Dos Santos et al.
Emerging evidence indicates potential adverse effects on infant neurodevelopment from exposure to glyphosate during prenatal and postnatal periods. This systematic review examines the scientific literature to explore links between prenatal/...
Tangeretin induces apoptosis and cell cycle arrest in thyroid cancer cells [0.03%]
金丝桃苷诱导甲状腺癌细胞凋亡和细胞周期阻滞
Yun-Hee Jeoung,Hong Kyu Lee,Seung-Hyeon Ahn et al.
Yun-Hee Jeoung et al.
Thyroid cancer is a malignant tumor whose incidence is increasing worldwide. While thyroid cancer is treatable and curable, a small number of cases can become metastatic when cancer cells originating in the thyroid gland spread to other par...
Chemically-induced histopathological progression in the polycystic ovary syndrome (PCOS)- A review [0.03%]
化学诱导的多囊卵巢综合征(Polycystic Ovary Syndrome, PCOS)病理进展概述
Mehjbeen Javed,Suramya,Shahzad Ahmad et al.
Mehjbeen Javed et al.
Polycystic ovary syndrome (PCOS) is the most common endocrine-gynecological disorder, affecting 4-10% of women of reproductive age. Although a fragment of the involved mechanism behind the PCOS occurrence is discovered, the exact etiology a...
Effect of red yeast rice on the growth of male SD rats: a 90-day feeding study [0.03%]
红曲霉菌对雄性SD大鼠生长影响的90天喂养试验
Hayoung Lee,Byungkyung Do,Hoonjeong Kwon
Hayoung Lee
Red yeast rice (RYR) is commonly used as colouring and flavouring agent in foods throughout East Asia. RYR contains monacolin K, a compound known to lower blood lipids level, which has led to its use as a health functional food in Korea. Ad...