Identification of optimal adenine and cytosine base editors for genome editing in Arabidopsis and soybean [0.03%]
用于拟南芥和大豆基因组编辑的最优腺嘌呤和胞嘧啶碱基编辑器鉴定
Yeong Yeop Jeong,Jun Hee Han,Jihyeon Yu et al.
Yeong Yeop Jeong et al.
Base editors, including adenine base editors (ABEs) and cytosine base editors (CBEs), are widely used in numerous organisms to introduce site-specific sequence modifications in genomic DNA without causing double-strand breaks (DSBs). Howeve...
Diagnosis and therapeutic targeting of quiescent cancer cells: road to conquer cancer recurrence [0.03%]
静息癌细胞的诊断与治疗靶向：克服癌症复发之路
Moon Jong Kim
Moon Jong Kim
Quiescent cancer cells (QCCs) are considered an origin of cancer recurrence and present an ongoing challenge in cancer treatment. Following anti-cancer therapy, non-proliferating, therapy-resistant QCCs have been detected as subsets of resi...
Exercise induces Mettl14 in iWAT but regulates browning and metabolism independently of Mettl14 [0.03%]
METTL14独立于运动诱导iWAT的褐变和能量代谢调节
Hye Jin Kim,Je Kyung Seong
Hye Jin Kim
Exercise is a key driver of metabolic enhancement, and the impact of exercise on methyltransferase-like14 protein (Mettl14)-mediated N6-methyladenosine (m6A) modification remains unexplored. This study investigates the role of Mettl14 in in...
SERPINA3 as a modulator of skin cell functionality in human dermal fibroblasts [0.03%]
人真皮成纤维细胞中 SERPINA3 在皮肤细胞功能中的调节作用
Young Du Choi,Young Un Kim,HyunJoon Gi et al.
Young Du Choi et al.
Skin aging is a complex biological process driven by intrinsic and extrinsic factors, leading to a progressive structural and functional decline. The balance between extracellular matrix (ECM) degradation and synthesis is critical for maint...
mTORC1 and STAT3 signaling are indispensable for in vitro TGFβ1-dependent three-dimensional (3D) tendon constructs [0.03%]
mTORC1和STAT3信号传导对体外TGFβ1依赖的三维(3D)腱结构的构建是必不可少的
Bon-Hyeock Koo,Aiden Smith,Kyu Sang Joeng
Bon-Hyeock Koo
Transforming Growth Factor-β1 (TGFβ1) is an established growth factor that regulates tenocyte differentiation, extracellular matrix production, and cell fate. We previously demonstrated its pivotal role in in vitro 3D tendon constructs fo...
LPS stimulation-induced regulation of LECT2 expression via TLR4 in hepatocytes [0.03%]
TLR4介导的LPS刺激诱导肝细胞LECT2表达调控作用机制研究
Ayoub El Bakiallah,Desy Simamora Damayanti,Rosana Nogueira et al.
Ayoub El Bakiallah et al.
Leukocyte cell-derived chemotaxin 2 (LECT2), a secreted protein, is implicated in various physiological and pathological processes. As a hepatokine, LECT2 is predominantly synthesized and secreted by hepatocytes, with elevated levels being ...
High-resolution detection of RPS24 microexon variations reveals novel splicing patterns in response to KRAS-targeted therapy in lung adenocarcinoma [0.03%]
高分辨率检测RPS24微外显子变异，揭示了肺腺癌对KRAS靶向治疗的新型剪接模式
Dahye Nam,Bin Tian,Jiyeon Park et al.
Dahye Nam et al.
Alternative splicing (AS) dysregulation is increasingly recognized as a critical factor in cancer progression and drug response. However, precisely detecting and characterizing complex splicing events, particularly those involving microexon...
Tat-GSTpi suppresses inflammatory responses by regulating ROS/MAPKs/apoptosis signaling pathways [0.03%]
Tat-GSTpi通过调节ROS/MAPKs/凋亡信号通路抑制炎症反应
Eun Ji Yeo,Min Jea Shin,Gi Soo Youn et al.
Eun Ji Yeo et al.
Glutathione S-transferase pi (GSTpi) is a phase II detoxifying enzyme that plays key roles in cellular processes. In a previous study, we have reported that cell permeable Tat-GSTpi can protect dopaminergic neurons against cell death. Howev...
Promiscuous enzyme SQOR in cellular metabolism and ferroptosis regulation [0.03%]
多功能酶SQOR在细胞代谢和铁死亡调控中的作用
Jumi Lee,Inhwan Yoo,Ihyeon Ahn et al.
Jumi Lee et al.
Ferroptosis, an iron-dependent form of programmed cell death, is primarily driven by the accumulation of lipid peroxides through radical generation, notably via the Fenton reaction. Emerging evidence highlights the intricate link between fe...
Erratum to: Celecoxib is the only nonsteroidal anti-inflammatory drug to inhibit bone progression in spondyloarthritis [0.03%]
Correction to: 集中式受理案件的法院是否更有效率？——基于最高人民法院申诉信访数据的分析
Jin Sun Choi,Ji-Young Kim,Min-Joo Ahn et al.
Jin Sun Choi et al.
[Erratum to: BMB Reports 2025; 58(3): 140-145, PMID: 39757202, PMCID: PMC11955732] The BMB Reports would like to issue a correction to an article published in BMB Rep. 58(3): 140-145, titled "Celecoxib is the only nonsteroidal anti-inflamma...
Published Erratum
BMB reports. 2025 Apr;58(4):190. DOI: 2025