Cdk1-dependent lamin aggregation underlies oxidative stress-induced nuclear shape abnormalities [0.03%]
氧化应激诱导的核形态异常源于由CDK1依赖性 lamins凝集引起的现象
Ju-Hyun Ahn,Min-Guk Cho,Abdul Basit et al.
Ju-Hyun Ahn et al.
Altered nuclear morphology, one of the characteristics of cancer cells, is often indicative of tumor prognosis. While reactive oxygen species (ROS) are known to induce nuclear morphology changes, mechanisms underlying these effects remain e...
Reverse beta-oxidation for biochemical production: insights into the functional properties of key enzymes [0.03%]
用于生物制造的逆β氧化：关键酶的功能属性的新见解
Areum Lee,Hyeoncheol Francis Son
Areum Lee
The reverse β-oxidation (rBOX) pathway is emerging as a promising alternative to fossil fuel-based chemical production, providing a versatile platform for the synthesis of various valueadded biochemicals. Efficient application of rBOX depe...
New insights to B cell tolerance involving the mechanosensitive ion channel Piezo1 [0.03%]
Piezo1机械敏感离子通道参与B细胞耐受的新见解
Youngjae Hong,Chaiwon Kim,Kihyuck Kwak
Youngjae Hong
B cell tolerance is critical for preventing autoimmunity, yet the mechanisms by which B cells discriminate self from non-self antigens remain incompletely understood. While early findings emphasize the role of classical antigen-mediated BCR...
Recent advances in single-cell bioinformatics for inferring higher-order chromatin contact maps [0.03%]
单细胞组学在高阶染色体互作图谱研究中的最新应用进展
Seung Kyun Noh,Minhyeok Lee,Hyobin Jeong
Seung Kyun Noh
DNA, a large molecule located in the nucleus, carries essential genetic information, including gene loci and cis-regulatory elements. Despite its extensive length, DNA is compactly stored within the limited space of the nucleus due to its h...
Ilimaquinone-induced lipophagy diminishes lipid accumulation via AMPK activation [0.03%]
Ilimaquinone诱导的脂质自噬通过活化AMPK减少脂质蓄积
Eun-Sun Yang,Se-Yun Cheon,Ji Yeong Park et al.
Eun-Sun Yang et al.
Lipid metabolism plays an important role in aging and longevity, and lipophagy-a specialized form of autophagy that targets lipid vesicles-regulates lipid homeostasis and alleviates metabolic diseases such as metabolic dysfunctionassociated...
Erratum to: Modulating CD226 and PD-(L)1 pathways improves CMV-specific CD8＋T cell responses in the absence of IL-2 [0.03%]
Correction to: 调节CD226和PD-(L)1信号轴可改善IL-2缺乏时的CMV特异性CD8+T细胞应答
Hye-In Sim,Yunju Jo,Hyejin Ahn et al.
Hye-In Sim et al.
[Erratum to: BMB Reports 2025; 58(7): 307-312, PMID: 40495489, PMCID: PMC12313400] BMB Reports recently published the article "Modulating CD226 and PD-(L)1 pathways improves CMV-specific CD8＋T cell responses in the absence of IL-2" (BMB Rep....
Published Erratum
BMB reports. 2025 Aug;58(8):369. DOI: 2025
The antioxidant effects of decursin inhibit EndMT progression through PI3K/AKT/NF-κB and Smad signaling pathways [0.03%]
抗氧化剂decursin通过PI3K/AKT/NF-κB和Smad信号通路抑制内皮-间充质转化（EndMT）进展的作用机制研究
Ran Kim,Sejin Kim,Hojin Kim et al.
Ran Kim et al.
Endothelial cells (ECs) undergo endothelial-to-mesenchymal transition (EndMT) during the pathophysiology of cardiovascular diseases, a complex cellular transdifferentiation process closely associated with increased oxidative stress under ad...
Metal-stabilized G-quadruplexes: biological insights and sensing applications [0.03%]
金属稳定的G-四联体：生物学见解及检测应用
Seongmin Kim,Dahoon Kim,Yoori Kim
Seongmin Kim
Repeat sequences account for approximately 45% of the human genome, and can produce noncanonical DNA secondary structures that include G-quadruplexes (G4s). Among these, G4s are unique, in that their formation and stability are largely infl...
Eunseok Kang,Rosa Haque,Hanseul Lee et al.
Eunseok Kang et al.
RNA modifications are key epigenetic alterations that play regulatory functions in RNA biology, including RNA stability and translation. Emerging evidence indicates that RNA modification is crucial for various physiological and pathological...
Ubiquitination and ubiquitin-like modifications in metabolic dysfunction-associated steatotic liver disease: mechanisms and implications [0.03%]
代谢功能异常相关性肝脂肪变性疾病中的泛素化及泛素样修饰：机制和意义
Hyunjin Rho,Uijin Kim,Jaewhan Song
Hyunjin Rho
Metabolic dysfunction-associated steatotic liver disease (MASLD) is a complex metabolic disorder that encompasses a spectrum of conditions, from simple hepatic steatosis to metabolicassociated steatohepatitis (MASH). MASH is characterized b...