Cinchonidine induces muscle weakness by inhibiting insulin-mediated IRS-1-AKT signaling pathway [0.03%]
长春定碱通过抑制胰岛素介导的IRS-1-AKT信号通路诱导肌肉无力
Mi Ran Byun,Sang Hoon Joo,Young-Suk Jung et al.
Mi Ran Byun et al.
Sarcopenia is an age-related condition marked by a reduction in muscle mass and strength, and it is associated with impaired muscle regeneration and differentiation. While diseases like cardiovascular and chronic liver disease can induce sa...
Comparative genome analysis of enterohemorrhagic Escherichia coli ATCC 43894 and its pO157-cured strain 277 [0.03%]
肠致病大肠杆菌ATCC 43894及其不含pO157的菌株277的基因组比较分析
Se Kye Kim,Yong-Joon Cho,Carolyn J Hovde et al.
Se Kye Kim et al.
Enterohemorrhagic Escherichia coli (EHEC) O157:H7 ATCC 43894 (also known as EDL932) has been widely used as a reference strain for studying the pathophysiology of EHEC. To elucidate the role of a large virulence plasmid pO157 and its relati...
Comparative Study
Journal of microbiology (Seoul, Korea). 2025 Dec;63(12):e2511015. DOI:10.71150/jm.2511015 2025
Synergistic anti-obesity effects of Bifidobacterium breve BR3 and Lactiplantibacillus plantarum LP3 via coordinated regulation of lipid metabolism and gut microbiota [0.03%]
通过协调调节脂质代谢和肠道菌群的协同减肥作用BR3和LP3细菌株的有效性
Misun Yun,Dooheon Son,Namhee Kim et al.
Misun Yun et al.
The global rise in obesity and its associated metabolic complications underscores the urgent need for safe and effective interventions. This study investigated the anti-obesity efficacy of a probiotic mixture containing Bifidobacterium brev...
Heeji Moon,Hokyoung Son
Heeji Moon
Pathogenic fungi pose major threats to both global food security and human health, yet the molecular basis of their virulence remains only partially understood. Beyond genetic and transcriptional control, emerging evidence highlights protei...
Proteolytic enzymes from Bacillus subtilis AB2 as antibiofilm adjuvants: Bioprocess optimization, mechanistic insights, and synergy with antibiotics [0.03%]
枯草芽孢杆菌AB2蛋白酶的抑菌膜活性研究：生物工艺优化、机制洞察及与抗生素的协同作用研究
Afra M Baghdadi
Afra M Baghdadi
Collagenase and keratinase are two important proteolytic enzymes with recognized applications in biotechnology and medicine, particularly in the enzymatic removal of necrotic tissue and the control of infection. In the present work, a soil ...
Mucilaginibacter florum sp. nov., isolated from the flower of Coreopsis grandiflora and Mucilaginibacter oryzagri sp. nov., isolated from rice paddy soil in Korea [0.03%]
来源于美国大花铁线莲花朵和韩国水稻土的两种粘液芽孢杆菌新种：花园粘液芽孢杆菌和稻田粘液芽孢杆菌
Parthiban Subramanian,Jun Heo,Daseul Lee et al.
Parthiban Subramanian et al.
Two aerobic, Gram-stain-negative, non-motile and rod-shaped bacterial strains designated GGG-R5T and M4-18T were isolated from flowers of golden wave (Coreopsis grandiflora) and rice paddy soil, respectively in the Republic of Korea. Both s...
Multi-omic profiling reveals the impact of keratinase kerZJ on mouse gut homeostasis [0.03%]
多组学谱型揭示角蛋白酶kerZJ对小鼠肠道稳态的影响
Xueqing Gan,Yijiao Wen,Si Chen et al.
Xueqing Gan et al.
Keratinase kerZJ is a multifunctional protease with potential as a feed additive and functional ingredient. Here we performed an integrated multi‑omics evaluation of its biosafety and impact on gut homeostasis in mice. Our findings confirm...
Metabolite-mediated mechanisms linking the urinary microbiome to bladder cancer [0.03%]
与膀胱癌相关的尿液微生物组的代谢中介机制
Thu Anh Trần,Ho Young Lee,Hae Woong Choi
Thu Anh Trần
Bladder cancer is the most common malignancy of the urinary tract and is a major health burden globally. Recent advances in microbiome research have revealed that the urinary tract harbors a resident microbial community, overturning the lon...
Lactiplantibacillus koreensis sp. nov. and Lactiplantibacillus kimchii sp. nov., isolated from kimchi, a traditional Korean fermented food [0.03%]
来源于传统韩国发酵食品泡菜的植物乳杆菌科两种新种：Lactiplantibacillus koreensis sp. nov. 和 Lactiplantibacillus kimchii sp. nov.
Min Ji Lee,Jisu Lee,Sohee Nam et al.
Min Ji Lee et al.
Two Gram-stain-positive, facultatively anaerobic, rod-shaped, and non-motile lactic acid bacterial strains, designated as strains CBA3605T and CBA3606T, were isolated from kimchi, a traditional Korean fermented food. Both strains were oxida...
Inhibition of cardiolipin biosynthesis partially suppresses the sensitivity of an Escherichia coli mutant lacking OmpC to envelope stress [0.03%]
部分抑制卡氏脂质生物合成可减弱缺乏ompC的埃希氏大肠杆菌突变体对包膜应激的敏感性
Dae-Beom Ryu,Umji Choi,Gyubin Han et al.
Dae-Beom Ryu et al.
Porins in the outer membrane (OM) of Gram-negative bacteria play two main functions: passage of various extracellular molecules and maintenance of membrane integrity. OmpC, a non-specific porin, is involved in both functions; however, the e...