Prebiotic potential of proso millet and quinoa: Effects on gut microbiota composition and functional metabolic pathways [0.03%]
小米和奇亚种子的益生潜力：对肠道菌群组成及功能代谢途径的影响
Jinwoo Kim,Jiwoon Kim,Yewon Jung et al.
Jinwoo Kim et al.
Prebiotics are indigestible dietary components that improve host health by stimulating the growth and metabolic activity of beneficial intestinal microbes. The whole grains are rich in non-digestible carbohydrates, which may confer prebioti...
Metabolic engineering of Saccharomyces cerevisiae for efficient utilization of pectin-rich biomass [0.03%]
用于有效利用富含果胶生物质的酵母代谢工程
Dahye Lee,Fransheska Semidey,Luping Xu et al.
Dahye Lee et al.
Pectin-rich biomass, derived from fruit and citrus processing waste, presents a promising yet underutilized resource for sustainable biofuel and biochemical production. Its low lignin content and high concentrations of fermentable sugars, i...
Inhibition of candidalysin production by methoxy-apo-enterobactin from Streptomyces ambofaciens CJD34 as a novel antifungal strategy against Candida albicans [0.03%]
链霉菌CJD34的甲氧基- apo-肠杆菌素通过抑制白色念珠菌半乳糖醇合成作为一种新的抗真菌策略
Eui-Seong Kim,Hyeongju Jeong,Mustansir Abbas et al.
Eui-Seong Kim et al.
Opportunistic fungal pathogens, responsible for over 300 million severe cases and 1.5 million deaths annually, pose a serious global health threat, especially in immunocompromised individuals. Among these, Candida albicans is a major cause ...
Phycobium rhodophyticola gen. nov., sp. nov. and Aliiphycobium algicola gen. nov., sp. nov., isolated from the phycosphere of marine red algae [0.03%]
来源于红藻菌圈的新型念珠蓝细菌Phycobium rhodophyticola gen. nov., sp. nov. 和Aliiphycobium algicola gen. nov., sp. nov.
Jeong Min Kim,Woonhee Baek,Byeong Jun Choi et al.
Jeong Min Kim et al.
Two Gram-stain-negative, strictly aerobic, non-motile, rod-shaped bacteria, designated D3-12ᵀ and G2-2ᵀ, were isolated from the phycosphere of marine red algae. Both strains exhibited catalase- and oxidase-positive activities. Strain D3-1...
Targeting innate immune sensors for therapeutic strategies in infectious diseases [0.03%]
针对感染性疾病治疗策略的固有免疫传感器靶向作用
Seyun Shin,Young Ki Choi,SangJoon Lee
Seyun Shin
The innate immune system relies on innate immune sensors, such as pattern recognition receptors (PRRs), to detect pathogens and initiate immune responses, crucial for controlling infections but also implicated in inflammatory diseases. Thes...
Inhibiting kinesin family member 20A disrupts Zika virus entry by blocking internalization [0.03%]
抑制动力蛋白家族成员20A可阻断寨卡病毒内吞从而抑制其入侵
Jeonghyeon Lee,Younghyun Lim,Hyeong-Rae Kim et al.
Jeonghyeon Lee et al.
Zika virus, a mosquito-borne virus, is associated with congenital birth defects and neurological complications. However, despite its significant public health threat, no approved vaccines or antiviral treatments are currently available. The...
Development of a CRISPR/Cas9 RNP-mediated genetic engineering system in Paecilomyces variotii [0.03%]
构巢曲霉CRISPR/Cas9 RNP遗传工程技术的开发
Hui-Gang Han,Rutuja Nandre,Hyerang Eom et al.
Hui-Gang Han et al.
A thermophilic strain of Paecilomyces variotii (MR1), capable of surviving temperatures above 40°C, was isolated from a paper mill and investigated as a host for heterologous protein production. To prevent environmental dissemination of sp...
Bacteroides celer sp. nov. and Bacteroides mucinivorans sp. nov., isolated from human feces, and the reclassification of Bacteroides koreensis Shin et al. 2017 and Bacteroides kribbi Shin et al. 2017 as later heterotypic synonyms of Bacteroides ovatus Eggerth and Gagnon 1933 (Approved Lists 1980) [0.03%]
从人类粪便中分离的拟杆菌属两种新物种：快择拟杆菌和粘液择菌以及韩国拟杆菌Shin et al. 2017和克里布拟杆菌Shin et al. 2017归类为与卵形拟杆菌Eggerth and Gagnon 1933（Approved Lists 1980）异同型异名的新分类
Ah-In Yang,Bora Kim,Woorim Kang et al.
Ah-In Yang et al.
Two novel, Gram-stain-negative, anaerobic, and non-motile bacterial strains, designated KFT8T and CG01T, were isolated from the feces of healthy individuals without diagnosed diseases and characterized using a polyphasic approach. Phylogene...
The photosensitizer DH-I-180-3 regulates intracellular bacterial growth by increasing the secretion of proinflammatory cytokines via the NF-κB- and MAPK-mediated signaling pathways and promoting phagosome maturation in Salmonella-infected mouse macrophages [0.03%]
光敏剂DH-I-180-3通过NF-κB和MAPK介导的信号通路增加促炎症细胞因子的分泌并促进沙门氏菌感染的小鼠巨噬细胞中吞噬体成熟以此调控胞内细菌生长
Hyo-Jung Kim,Eui-Kwon Jeong,Hyo-Ji Lee et al.
Hyo-Jung Kim et al.
Photodynamic therapy (PDT) is a known strategy for treating cancer; in PDT, photosensitizers are activated by light stimulation and then induce reactive oxygen species (ROS) production to damage cancer tissues. Recently evidence has shown t...
Microbial signatures in oral sites of patients with primary Sjögren's syndrome: Association with salivary gland hypofunction [0.03%]
原发性舍格伦综合征患者口腔部位的微生物特征与唾液腺功能减退的关系
Sarah Kamounah,Arjun Sarathi,Christiane Elisabeth Sørensen et al.
Sarah Kamounah et al.
This study aimed to determine if the microbiota in four different oral sites and the oral health status differ between patients with primary Sjögren's syndrome (pSS), non-pSS sicca symptoms, and healthy controls. All participants underwent...