Evaluation of nausea induced by trifluridine/tipiracil in metastatic colorectal cancer treatment [0.03%]
评估转移性结直肠癌治疗中由三氟胸苷/提帕西林引起的恶心
Yoshitaka Saito,Yoh Takekuma,Yoshito Komatsu et al.
Yoshitaka Saito et al.
Trifluridine/tipiracil (FTD/TPI) frequently induces chemotherapy-induced nausea and vomiting (CINV). As evidence of factors associated with CINV in oral chemotherapeutic agents is limited, we aimed to assess factors for nausea development i...
Silvano Esposito,Chiara DAmore,Flora Salzano et al.
Silvano Esposito et al.
Mpox is an emerging zoonosis that was first described in African animals, including monkeys, small rodents, and Gambian marsupial rats. It has since been identified as a sexually transmitted infection among humans. The disease is characteri...
Evaluating the effect of neoadjuvant chemotherapy on surgical outcomes in breast cancer patients: a systematic review study [0.03%]
新辅助化疗对乳腺癌患者手术效果的影响评估:一项系统综述研究
Ali Tayebi,Adnan TizMaghz,Mahmood Gorjizad et al.
Ali Tayebi et al.
As a systematic review, this study addresses a gap in the literature by evaluating both the short-term and long-term outcomes of breast cancer patients undergoing neoadjuvant chemotherapy (NAC). The purpose of the current study was to evalu...
Exploring the role of quercetin on doxorubicin and lapatinib-mediated cellular and mitochondrial responses using in vitro and in silico studies [0.03%]
使用体外和计算机模拟研究探索黄酮对多柔比星和拉帕替尼介导的细胞和线粒体反应的作用
Ali Ergüç,Gökay Albayrak,Muhammed Tilahun Muhammed et al.
Ali Ergüç et al.
Doxorubicin (DOX) and lapatinib (LAP) have been reported to cause liver toxicity. The roles of mitochondrial and cellular responses in DOX and LAP mediated-hepatotoxicity have not been investigated with or without quercetin (QUE) in HepG2 c...
The relationship between body mass index and survival in patients with renal cell carcinoma treated with nivolumab [0.03%]
使用尼伏鲁单抗治疗的肾细胞癌症患者身体质量指数与生存率的关系研究
Rumeysa Çolak,İlkay Gültürk,Gülhan Dinç et al.
Rumeysa Çolak et al.
Introduction: Immunotherapies have increased the therapeutic options for patients with metastatic renal cell carcinoma (mRCC), but the absence of prognostic indicators remains unresolved. We assessed the potential associa...
Successful treatment with oxaliplatin and programmed cell death protein 1 inhibitor in recurrent advanced endometrial carcinoma with mismatch repair defects: a case report and literature review [0.03%]
奥沙利铂和程序性细胞死亡蛋白1抑制剂成功治疗具有错配修复缺陷的复发晚期子宫内膜癌一例及文献复习
Jian Qiu,Tian Ding,Mingyue Cao et al.
Jian Qiu et al.
The incidence of endometrial cancer (EC), a widely prevalent gynecological malignancy, is witnessing a global surge. Although early-stage cancer demonstrates promising outcomes, advanced cancer is associated with an unfavorable prognosis. N...
Comparison of Syrian generic ceftriaxone sodium preparations for injection: BHT content and its implications [0.03%]
叙利亚版注射用头孢曲松钠制剂的比较:BHT含量及其影响
Abeer Srour,Khawla Alamere,Ghassan Abo Chameh et al.
Abeer Srour et al.
This study aimed to evaluate the compatibility of generic ceftriaxone sodium preparations with various rubber closures used in pharmaceutical packaging, focusing on the release of butylated hydroxytoluene (BHT), an antioxidant present in ru...
Sai Harini Chandrasekaran,Pugazhendi Inban,Reeju Maharjan et al.
Sai Harini Chandrasekaran et al.
Although recent advancements in cancer treatment have significantly improved survival rates, they have also raised concerns regarding severe adverse effects, including cardiotoxicity. We conducted a prospective study at Dayanand Medical Col...
Perihan Perkin,Serhat Sekmek,Dogan Bayram et al.
Perihan Perkin et al.
Immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment but are associated with immune-related adverse events (irAEs). Pembrolizumab, an anti-PD-1 antibody, is widely used in non-small cell lung cancer (NSCLC), yet immune t...
The gene-panel obtained by anti-PD-1 monotherapy for melanoma reveals prognostic markers and therapeutic targets [0.03%]
通过抗PD-1单药治疗获得的黑色素瘤基因组揭示了预后标志物和治疗靶点
Miaomiao Wang,Zhike Zhou,Yingying Wang et al.
Miaomiao Wang et al.
To search for key drug resistance biomarkers and potential chemotherapeutic agents for combination therapy in melanoma patients. The common up-regulated differentially expressed genes were acquired from two cohort studies, GSE91061 and PRJE...