Research progress on eravacycline: from pharmacokinetics/pharmacodynamics to the practice of individualized therapy [0.03%]
Eravacycline的研究进展：从药动/药效学到个体化治疗实践
Chao Meng,Jingjing Lan,Shuaijia Wang et al.
Chao Meng et al.
Eravacycline is a fully synthetic, fluorinated third-generation tetracycline with broad-spectrum antibacterial activity, approved for the treatment of complicated intra-abdominal infections(cIAI). Clinical studies have demonstrated favorabl...
Risk of peripheral edema in cancer patients receiving MET inhibitors: a systematic review and meta-analysis [0.03%]
MET抑制剂治疗癌症患者外周水肿的风险：系统评价和meta分析
Li Jing,Wen Xiong,Lina An
Li Jing
Although MET inhibitors are increasingly used in cancer treatment, the overall risk and key determinants of treatment-related peripheral edema remain insufficiently characterized. We performed a systematic review and meta-analysis of random...
Taxane-induced macular oedema: disproportionality and timing analyses using FAERS and JADER [0.03%]
他莫昔芬引起的黄斑水肿：FAERS和JADER数据库的 disproportionality和timing分析
Naohito Ide,Yoshifumi Kudo,Ken-Ichi Sako et al.
Naohito Ide et al.
Taxanes such as paclitaxel and docetaxel are widely used in malignancies but may cause rare ophthalmic toxicities, including macular oedema. This study clarified occurrence patterns and time to onset by analysing the FDA Adverse Event Repor...
Acquired CD74-ROS1 fusion-mediated osimertinib resistance successfully treated with osimertinib and crizotinib: a case report [0.03%]
获得性CD74-ROS1融合介导的奥希替尼耐药成功采用奥希替尼和克唑替尼治疗一例报告
Ali Kaan Güren,Erkam Kocaaslan,Yeşim Ağyol et al.
Ali Kaan Güren et al.
In EGFR T790M-mutant lung adenocarcinoma, the strong and early clinical responses achieved with osimertinib may be limited by the emergence of diverse resistance mechanisms over time. In this case report, we describe an acquired CD74-ROS1 f...
The role of gut microbiome in chemoresistance property development in colorectal cancer tissue and its novel therapeutic strategies [0.03%]
肠道微生物组在结直肠癌组织化疗耐药特性发展中的作用及其新型治疗策略
Pratikshya Parhi,Amrita Banerjee,Hrudayanath Thatoi
Pratikshya Parhi
Colorectal cancer remains the second contributor to cancer-related mortality worldwide. Despite various advances in chemotherapeutic approaches, chemoresistance still poses a significant risk, hampering the effectiveness of the treatment. R...
Cytofluorimetric study of cerebrospinal fluid at staging of diffuse large B cell lymphoma [0.03%]
弥漫性大B细胞淋巴瘤分期时脑脊液的流式细胞仪研究
O Annibali,C Bancone,V Tomarchio et al.
O Annibali et al.
Central nervous system (CNS) involvement is a devastating manifestation of diffuse large B-cell lymphoma (DLBCL), historically associated with poor outcomes. However, the criteria for accurately identifying patients at highest risk of lepto...
Disseminated intravascular coagulation (DIC) associated with immune checkpoint inhibitor therapy: a real-world study of the FDA adverse event reporting system [0.03%]
美国食品药品监督管理局不良事件报告系统中与免疫检查点抑制剂治疗相关的弥散性血管内凝血：一项真实世界研究
Xia Yang,Ming Hu,Quanyao Feng et al.
Xia Yang et al.
While immune checkpoint inhibitor (ICI)-related adverse effects have gained increasing attention, disseminated intravascular coagulation (DIC) remains understudied. This retrospective study analyzed the FAERS database from 2011 to 2025 usin...
Antiviral drug resistance in cytomegalovirus complicating hematopoietic stem cell transplantation: prevalence, genotypic analysis and novel UL97/UL54 variants [0.03%]
造血干细胞移植后人类巨细胞病毒的抗病毒药物耐药性：发生率、基因型分析和新型UL97 / UL54变异体
Şerife Çevik,Selma Gökahmetoğlu,Ömür Mustafa Parkan et al.
Şerife Çevik et al.
This study investigated antiviral resistance by sequencing UL97 and UL54 in cytomegalovirus (CMV) strains from haematology and hematopoietic stem cell transplant (HSCT) patients. Fifty-one samples from 48 patients (21 paediatric and 27 adul...
Effects of anthracyclines on arteriosclerosis and the protective effect of dexrazoxane in breast cancer patients [0.03%]
蒽环类药物对动脉粥样硬化的影响及艾德沙唑烷的心保护作用综述——以乳腺癌患者为例
Demet Isik Bayraktar,Recep Turkel,Guzin Demirag
Demet Isik Bayraktar
Anthracyclines are essential agents in the treatment of breast cancer. This study investigated the effect of anthracyclines on arteriosclerosis. The study group consisted of 60 patients not receiving anticoagulants and was divided into two ...
Short-term neurotoxicity trajectory in patients with thoracic cancers receiving triweekly albumin-bound paclitaxel [0.03%]
胸部肿瘤患者接受每周三次白蛋白结合型紫杉醇短期神经毒性轨迹分析
Yi Huang,Lijuan Feng,Jing Hu et al.
Yi Huang et al.
This study aimed to investigate the short-term trajectory of peripheral neuropathy in patients receiving triweekly albumin-bound paclitaxel (nab-paclitaxel) chemotherapy. 235 patients were recruited from March to August 2024, of whom 65.1% ...