Rihua Zeng,Jianning Chen
Rihua Zeng
Gastric cancer (GC) persists as a leading cause of global cancer morbidity and mortality, with its pathogenesis intricately linked to epigenetic dysregulation. Emerging research specifies the novelty of these mechanisms-including DNA methyl...
Ribosome biogenesis rate, a parameter of sensitivity to chemotherapeutic drugs inhibiting rRNA synthesis [0.03%]
核糖体生物发生率，一种化疗药物抑制rRNA合成敏感性的参数
Davide Treré,Lorenzo Montanaro,Massimo Derenzini et al.
Davide Treré et al.
Many drugs currently used in cancer chemotherapy exert their toxic action mainly by inhibiting ribosome biogenesis (RiBi). This is due to the fact that after inhibition of rRNA transcription ribosomal proteins, no longer used for ribosome b...
A novel approach in the identification of microRNAs in malignant pleural effusion for lung cancer diagnosis [0.03%]
一种通过恶性胸腔积液鉴定微小RNA以诊断肺癌的新方法
Jesús Valencia-Cervantes,Gustavo Ramirez-Martínez,Margarita Isabel Palacios-Arreola et al.
Jesús Valencia-Cervantes et al.
Introduction: Pleural effusion, an atypical accumulation of fluid in the pleural space, has been identified as a potential indicator of several diseases, including lung cancer. The presence of biomarkers in malignant pleu...
Irene Possenti,Stefano Miotti,Silvano Gallus et al.
Irene Possenti et al.
Introduction: Oral cavity and pharyngeal cancer (OPC) affects over 580,000 people globally each year, with tobacco and alcohol being key risk factors. This meta-analysis quantifies the excess risk of OPC associated with c...
Surgical cytoreduction versus systemic therapy in patients with metastatic gastroenteropancreatic neuroendocrine neoplasms (GEP-NENS): a national cancer database analysis (NCDB) [0.03%]
手术细胞减灭术与系统治疗在胃肠道和胰腺神经内分泌肿瘤(MGA-PNETS)患者中的比较：全国癌症数据库分析(NCDB)
Amr Mohamed,Fasih A Ahmed,Omkar Pawar et al.
Amr Mohamed et al.
Background: The optimal role of surgical cytoreduction in metastatic gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) remains uncertain, as supporting evidence is largely retrospective and rarely compares surger...
Universal vs. ASCO guidelines-based germline genetic testing for newly diagnosed breast cancer patients in resource-restricted settings [0.03%]
低资源条件下基于通用标准和ASCO指南的新发乳腺癌患者遗传咨询筛查研究
Hikmat Abdel-Razeq,Faris Tamimi,Sarah Abdel-Razeq et al.
Hikmat Abdel-Razeq et al.
Background: A significant subset of breast cancer cases is attributable to inherited pathogenic genetic variants. Germline genetic testing (GGT), particularly for BRCA1 and BRCA2, represents a critical tool for precision ...
Lights and shades of front-line treatment with covalent BTK inhibitors combined with venetoclax in patients with chronic lymphocytic leukemia [0.03%]
共价BTK抑制剂联合维奈克拉作为慢性淋巴细胞白血病一线治疗的疗效及安全性分析
Andrea Visentin,Francesca R Mauro
Andrea Visentin
This review focused on trials investigating the front-line covalent BTK inhibitors (cBTKi) and venetoclax (V) combination administered in a fixed-duration (CAPTIVATE, GLOW, AMPLIFY trials) or minimal residual disease (MRD)-guided manner (MD...
Diagnostic pitfalls: soft-tissue sarcomas initially misdiagnosed as benign vascular anomalies-a case report and systematic review [0.03%]
诊断陷阱：最初被误诊为良性血管异常的软组织肉瘤一例报告及系统回顾
Malgorzata Styczewska,Weronika Lyzinska,Stanislaw Maria Wardecki et al.
Malgorzata Styczewska et al.
Introduction: Vascular anomalies (VAs), comprising vascular tumors and malformations, are commonly diagnosed based solely on clinical evaluation and imaging. Soft-tissue sarcomas (STSs) may mimic VAs clinically and radiol...
Temporal changes in tongue color during immune checkpoint inhibitor therapy in patients with non-small-cell lung cancer: a prospective observational study using digital tongue diagnosis [0.03%]
数字舌诊断在非小细胞肺癌免疫检查点抑制剂治疗中观察舌色变化的前瞻性研究
Eunbyul Cho,Woosu Choi,Jun Hyeok Lim et al.
Eunbyul Cho et al.
Background: Tongue diagnosis (TD), a key component of traditional East Asian medicine, employs a unique pattern-based diagnostic system. Digital TD enables quantitative assessment of tongue characteristics, like body and ...
DNA methylation as prognostic factors in non-muscle-invasive bladder cancer: a systematic review and meta-analysis [0.03%]
DNA甲基化在非肌层浸润性膀胱癌中的预后价值：系统评价和 Meta 分析
Vishwajeet Singh,Mukul Kumar Singh,Anil Kumar et al.
Vishwajeet Singh et al.
Introduction: Early prognostication in non-muscle-invasive bladder cancer (NMIBC) is essential for optimizing therapy and follow-up. Epigenetic mechanisms, particularly DNA methylation, have emerged as promising biomarker...