CAR-T cell therapy in glioblastoma: from αβ to γδ T-cell platforms [0.03%]
从αβ到γδT细胞平台：嵌合抗原受体T细胞治疗胶质母细胞瘤
Costanza Dieli,Roberta Costanzo,Anna Maria Corsale et al.
Costanza Dieli et al.
Glioblastoma multiforme (GBM) remains a highly aggressive brain tumor with limited treatment options and poor survival. The persistent clinical failure has driven interest in novel, immune-based strategies with higher specificity and greate...
Risk factors for return to work in workers who experienced cancer: a systematic review with meta-analysis [0.03%]
癌症患者的返工风险因素：系统回顾和荟萃分析
M Franco,F Buscema,A Catalano et al.
M Franco et al.
Background: The number of people who have experienced cancer is increasing, and by 2040 cases are expected to rise by 40%, with a high prevalence among working-age individuals. Many people who experienced cancer (pwEC) fa...
Bidirectional regulatory mechanisms and therapeutic prospects of tumor hypercoagulable state and immunosuppressive tumor microenvironment [0.03%]
肿瘤高凝状态与免疫抑制性肿瘤微环境的双向调控机制及治疗前景
Yongli Lai,Ruyu Qin,Zhaidong Liu
Yongli Lai
The tumor hypercoagulable state (THS) is an acquired and persistent prothrombotic condition driven by the tumor and its microenvironment. An immunosuppressive tumor microenvironment (TME) is a local microenvironment that suppresses antitumo...
Artificial intelligence-driven multimodal fusion for precision diagnosis and personalized management of breast cancer [0.03%]
基于人工智能的多模态融合在乳腺癌精准诊断和个性化管理中的应用研究
Mingyu Zhang,Juhang Chu,Zixin Wang et al.
Mingyu Zhang et al.
Breast cancer is the most common malignancy among women worldwide, characterized by pronounced heterogeneity across molecular profiles, imaging phenotypes, and the tumor microenvironment. As precision oncology continues to advance, diagnost...
Cardio-oncology in multidisciplinary synergy: addressing the rising burden of cancer therapy-related cardiovascular toxicity (CTR-CVT) in advancing oncology practices [0.03%]
多学科协作中的心脏肿瘤学：在肿瘤学实践中解决不断加重的癌症治疗相关心血管毒性的负担问题
Putri Dwi Astuti,Eko Adhi Pangarsa,Andreas Arie Setiawan et al.
Putri Dwi Astuti et al.
Introduction: Improvements in cancer detection and the development of modern anticancer therapies have markedly increased survival rates among patients with malignancies, resulting in a rapidly expanding survivor populati...
Association of MMP-2 and hematological parameters with breast cancer metastasis: a cross-sectional study in Central Java, Indonesia [0.03%]
基质金属蛋白酶-2和血液学参数与乳腺癌转移的关系：印度尼西亚中爪哇的一次横断面研究
Alyssa Imani,Yan Wisnu Prajoko,Rudi Nirwantono et al.
Alyssa Imani et al.
Background: Breast cancer metastasis remains a major contributor to morbidity and mortality, partly due to the disease's marked biological heterogeneity. Identification of reliable biomarkers associated with metastatic pr...
Efficacy and safety of PD-1 inhibitors in recurrent or metastatic squamous cell carcinoma of the head and neck: a systematic review and meta-analysis [0.03%]
复发或转移性头颈部鳞癌中PD-1抑制剂的疗效和安全性：系统评价和Meta分析
Abdullah Alabbasi,Muhanad Alzahrani,Ziyad Alzahrani et al.
Abdullah Alabbasi et al.
Background: Conventional cytotoxic regimens for recurrent or metastatic head and neck squamous cell carcinoma (R/M HNSCC) offer limited durable benefit and are associated with significant toxicity. Immune checkpoint inhib...
Diagnostic utility of FAPI PET/CT in radioiodine-refractory thyroid cancer and TENIS syndrome: a systematic review [0.03%]
用于放射性碘难治性甲状腺癌和TENIS综合征诊断的FAPI-PET/CT系统综述
Akram Al-Ibraheem,Saad Ruzzeh,Ahmad Al-Muhtaseb et al.
Akram Al-Ibraheem et al.
Background: Fibroblast activation protein inhibitor (FAPI) positron emission tomography/computed tomography (PET/CT) has emerged as a promising molecular imaging modality with favorable lesion-to-background contrast acros...
Signaling pathway mechanisms in pancreatic ductal adenocarcinoma tumor microenvironment and emerging targeting strategies for improved prognosis [0.03%]
胰腺导管腺癌肿瘤微环境中的信号转导机制及改善预后的新兴靶向策略
Tosin Akinsipe,Caroline O Odewumi,Lekan Latinwo et al.
Tosin Akinsipe et al.
Pancreatic ductal adenocarcinoma (PDAC) remains one of the most lethal malignancies, characterized by a dense desmoplastic stroma and a profoundly immunosuppressive tumor microenvironment (TME). The TME plays a major role in tumor progressi...
Applications of large language models in tumor boards: a systematic review [0.03%]
肿瘤委员会中大型语言模型的应用：一项系统综述
Benjamin Konzmann,Maurice Henkel,Christian Breit et al.
Benjamin Konzmann et al.
Background: Multidisciplinary tumor boards (MDTs) are the gold standard for cancer care but currently face significant pressure from rising case volumes and the increasing complexity of precision medicine. Large Language ...