Bertrand Jordan
Bertrand Jordan
Serial cloning of mice by nuclear transfer has been pursued for 20 years and almost 60 successive generations by a highly dedicated Japanese team. Cloning has been successful up to the 57th generation, although with increasing difficulty fr...
[Long COVID: between a syndromic framework and an etiological imperative] [0.03%]
[长新冠：“综合征框架”与“病因决定论”之间]
Solenn Tanguy
Solenn Tanguy
Our response to the article "Long COVID: a long story" by Ilana Löwy aims to reiterate the fundamental principles of the definition of Long COVID, focusing on its viral etiology. It emphasizes that the health crisis linked to SARS-CoV-2 ca...
[Philippe Lazar: rigor, high standards, commitment, and an ethics of relationships] [0.03%]
[菲利普·拉扎尔：严格 要求 高标准 严谨 性和 关系伦理]
Hervé Chneiweiss
Hervé Chneiweiss
[Mitochondria] [0.03%]
[线粒体]
Anna Salvetti
Anna Salvetti
[The Edmonton transplantation protocol, 25 years later: toward remission of type 1 diabetes?] [0.03%]
埃德蒙顿方案实施25年之后：1型糖尿病临床缓解之道？
Meriem Fassy El Fehri,Mourad Ferdaoussi
Meriem Fassy El Fehri
Type 1 diabetes is a disease caused by the autoimmune destruction of insulin-secreting pancreatic beta cells. The replacement of beta cells according to the Edmonton protocol has opened new therapeutic avenues for restoring physiological re...
[Bioinformatics and omics analyses: chronology of a new scientific approach] [0.03%]
[生物信息学和组学分析：一种新的科学研究方法的历程]
Sylvère Bastien,Marouchka Gourinovitch,François Vandenesch et al.
Sylvère Bastien et al.
From the early debates of the 1940s-1970s on the nature of the genetic information carrier - opposing proteins and DNA - to the rise of "omics" approaches now widely used to explore the complexity of genomes and their expression, molecular ...
Anne-Marie Moulin
Anne-Marie Moulin
[The 2025 Nobel Prize: regulatory T lymphocytes, the long-neglected "immunosuppressive cells". A brief history of a scientific renaissance and its emergence in France] [0.03%]
【2025年诺贝尔奖：长期被忽视的“免疫抑制细胞”调节性T淋巴细胞】科学复兴简史及其在法国的崛起
José L Cohen
José L Cohen
The 2025 Nobel Prize in Physiology or Medicine was awarded jointly to Mary Brunkow, Fred Ramsdell and Shimon Sakaguchi for characterizing regulatory T cells (Tregs) and identifying the FOXP3 gene as their "master regulator". This work rehab...
[Contributions of seeding amplification assays to the diagnosis of synucleinopathies] [0.03%]
[种子放大试验在突触核蛋白病诊断中的应用价值]
Emma Lamard,Daisy Bougard
Emma Lamard
Synucleinopathies comprise three distinct disorders: Parkinson's disease, Lewy body dementia and multiple system atrophy, all of which involve the pathological aggregation of a protein called alpha-synuclein (α-syn). In order to establish ...
Mouna Chajadine,Ludivine Laurans,Soraya Taleb
Mouna Chajadine
Tryptophan (Trp), an essential amino acid, plays a central role in metabolism, inflammation, immunity, and energy homeostasis. It is primarily metabolized through the kynurenine, indole, and serotonin pathways, generating metabolites with e...