Activity-dependent metabolic vulnerability in the APPPS1 Alzheimer's disease mouse model during isoflurane anesthesia [0.03%]
异氟醚麻醉下APPPS1阿尔茨海默病小鼠模型中活性依赖的代谢脆弱性研究
Jonas Schunack,Georg Riepe,Kathrin Textoris-Taube et al.
Jonas Schunack et al.
General anesthesia is an essential component of modern surgical and diagnostic care. Although it is overall safe in younger and healthy individuals, the situation is markedly different in patients with underlying neurological conditions lik...
Corrigendum to "Chronic sarpogrelate treatment improves renal sympathetic hyperactivity in experimental diabetes"[Biomed. Pharmacother. 176 (2024) 116814] [0.03%]
“慢性沙普格雷特治疗改善实验性糖尿病肾交感神经活性过高”[Biomed. Pharmacother. 176 (2024) 116814]的勘误表
Juan Francisco Fernández-González,José Ángel García-Pedraza,Anaïs Clara Terol-Úbeda et al.
Juan Francisco Fernández-González et al.
Iron biomarkers for prognosis, diagnosis, and therapeutic insight in colorectal cancer [0.03%]
铁生物标志物在结直肠癌预后、诊断和治疗洞察中的作用
Amani Benamor,Peter Kubatka,Dietrich Büsselberg
Amani Benamor
Background: Colorectal cancer (CRC) is a significant global health concern. It ranks as the third most common cancer, accounting for about 10% of all cancer cases, with projections estimating a substantial increase in thi...
Intravenous immunoglobulin therapy in viral infections: Lessons learned from COVID-19 [0.03%]
COVID-19病毒性感染中的静脉注射免疫球蛋白治疗：经验与教训
Meryem Alaka,Edouard Tuaillon,Benoit Desnues
Meryem Alaka
Objectives: Intravenous immunoglobulin (IVIg) exerts both antiviral and immunomodulatory effects, but its role in viral infections remains incompletely defined. This review aims to provide an integrated overview of IVIg m...
Cuminaldehyde alleviates inflammation in isoproterenol-induced acute myocardial infarction through Nrf-2/HO-1 and NF-κB signaling pathways [0.03%]
肉豆蔻醛通过Nrf-2/HO-1和NF-κB信号通路缓解异丙肾上腺素诱导的急性心肌梗死炎症反应
Shervin Prince Stanely,Jibu Thomas,Reya Issac
Shervin Prince Stanely
Myocardial infarction (MI) is a leading cause of death, and the limited efficacy of current treatments pushes the exploration of novel drug candidates.The purpose of this study was to assess the anti-inflammatory effects of cuminaldehyde, a...
Stem cell-derived exosome therapy for traumatic brain injury and its auditory complications [0.03%]
间充质干细胞来源的外泌体治疗创伤性脑损伤及其听觉并发症的研究进展
Haitao Zhang,Maoxiang Xu,Boyu Cai et al.
Haitao Zhang et al.
Traumatic brain injury poses substantial public health and socio-economic threat globally. Hearing loss is one of the most common sensory complications of TBI. Post-traumatic hearing handicap causes impairment in cognition and communication...
Amelioration of obesity-induced testicular dysfunction and structural damage by ganoderma lucidum polysaccharides and triterpenoids in rats: Correlation with Nrf2-mediated antioxidant response [0.03%]
灵芝多糖和三萜改善肥胖大鼠睾丸功能障碍和结构损伤：与Nrf2介导的抗氧化反应的相关性研究
Li Yanhong,Liang Wei,Han Yunlin et al.
Li Yanhong et al.
Obesity is a global health crisis and a critical risk factor for male infertility, impairing testicular structure and function through hormonal imbalance and oxidative stress. Current therapeutic strategies are often unsatisfactory due to l...
Bidirectional microbiota-cancer crosstalk: Emerging platforms for advanced diagnostics and precision therapeutics in oncology [0.03%]
双向微生态-肿瘤互作：肿瘤学精准诊断和治疗的新兴平台
Mahtab Moshref-Javadi,Ghazale Ahmadbeigi,Hanieh Ataollahi et al.
Mahtab Moshref-Javadi et al.
Cancer is among the major causes of morbidity and mortality worldwide, and current treatment methods are limited by various drawbacks such as drug resistance, non-specificity, and differences among patients. With recent developments in this...
Biomaterials for women's health: Recent progress in nanomaterials and innovative therapies for endometriosis treatment [0.03%]
用于女性健康的生物材料：治疗子宫内膜异位症的纳米材料和创新疗法的新进展
Olga Urbanek,Magdalena Osial,Angelika Zaszczyńska et al.
Olga Urbanek et al.
Endometriosis is a chronic inflammatory condition characterized by the presence of endometrial-like tissue outside the uterine cavity. Despite significant advances in understanding its pathophysiology, the clinical management of endometrios...
Preliminary electrochemical study of Ap3A and Ap4A potential role in enhancing allicin-induced DNA denaturization and susceptibility to structure damage [0.03%]
Ap3A和Ap4A在增强蒜素诱导的DNA变性和结构损伤敏感性中的电化学初步研究
Oskar Szczepaniak,Małgorzata Pietrowska-Borek
Oskar Szczepaniak
Thiopolysulfides (TPS) are a group of organic sulphur compounds and are a part of secondary metabolites produced by plants of the Alliaceae family. A key representative compound of TPS is allicin, which has documented bacteriostatic propert...