First Report of (E)-1-Phenyl-3,7-dimethyl-2-octen-1-ol and N-propyl-4-methoxycinnamamide from Aegle marmelos unripe fruit: Isolation, characterization and mechanistic evaluation of proton pump inhibitory and antioxidant activities [0.03%]
从木果番荔枝未成熟的果实中首次鉴定到(E)-1-苯基-3,7-二甲基-2-辛烯-1-醇和N-丙基-4-甲氧基肉桂酰胺:分离、表征及抗质子泵和抗氧化活性的作用机制研究
Ayesha Tasnim Sinthi,Mst Shahnaj Parvin,Md Sayedul Islam Shakib et al.
Ayesha Tasnim Sinthi et al.
Aegle marmelos (L.) Corr. (Rutaceae) is a medicinally important tree widely used across South Asia for the treatment of gastrointestinal disorders including peptic ulcers, diarrhea, and dysentery. Beyond its antiulcer applications, the plan...
Therapeutic potential of antisense oligonucleotides in hematological malignancies [0.03%]
反义寡核苷酸在血液系统恶性肿瘤治疗中的潜力
Elie Cousin,Agathe Picard,Elfie Perrudin et al.
Elie Cousin et al.
Antisense oligonucleotides (ASOs) are short synthetic oligonucleotides composed of DNA, RNA, or chemically modified nucleotides, that represent a promising class of therapeutics for personalized medicine. This review synthesizes the clinica...
Myosin light chain phosphatase (MLCP), a type I phosphatase: Key regulator of vascular tone and an attractive target for novel therapeutic strategies in cardiovascular medicine [0.03%]
肌轻链磷酸酶(MLCP),一种I型磷atase:血管张力的关键调节因子及心血管医学中潜在的新治疗策略靶点
Nikola R Lazarov,Kamelya Bratoeva,Timm Schreiber et al.
Nikola R Lazarov et al.
The maintenance of stable vascular tone is functionally important for buffering flow and redistributing blood oxygen and glucose to match the metabolic demands of organs and tissues. As the tone of other hollow organs, build by smooth muscl...
Carnosic acid and carnosol promote lipid mediator class-switching toward inflammation resolution in human macrophages [0.03%]
肉猪酸和杨梅素促进人类单核细胞向炎症消退的脂质介质类型转换
Vivien Nischang,Bill J Perkowski,Lukas Peltner et al.
Vivien Nischang et al.
Lipid mediators (LM), formed from polyunsaturated fatty acids (PUFA) through cyclooxygenase- and lipoxygenase (LOX)-dependent pathways, contribute to all stages of inflammation and are thus valuable targets for drugs that intervene with inf...
Corrigendum: "Sea cucumber-derived extract can protect skin cells from oxidative DNA damage and mitochondrial degradation, and promote wound healing" [Biomed. Pharmacother. 180 (2024) 117466] [0.03%]
勘误:海参提取物可保护皮肤细胞免受氧化性DNA损伤和线粒体降解,并促进伤口愈合[Biomed. Pharmacother. 180 (2024) 117466]
Bismoy Mazumder,Meng Lu,Hassan Rahmoune et al.
Bismoy Mazumder et al.
Dual bispecific protein engager-armed T cells targeting BCMA and B7-H3 overcome antigen heterogeneity in multiple myeloma [0.03%]
双特异性蛋白武装的T细胞靶向BCMA和B7-H3可克服多发性骨髓瘤中的抗原异质性
Thanida Chanpong,Nunghathai Sawasdee,Kamonlapat Supimon et al.
Thanida Chanpong et al.
Multiple myeloma (MM) remains an incurable plasma cell malignancy, with most patients ultimately progressing to relapsed or refractory MM (RRMM) despite therapeutic advances. Antigen heterogeneity and immune escape, particularly the loss of...
Evaluating the cardiometabolic impact of Janus-kinase inhibition: An experimental analysis of Tofacitinib's therapeutic potential in a rodent model [0.03%]
Janus激酶抑制的 cardiometabolic 影响评估:Tofacitinib 在啮齿动物模型中的治疗潜力实验分析
Vera Tarjányi,Anna Szilágyi,Réka Szekeres et al.
Vera Tarjányi et al.
Background: Rheumatoid arthritis (RA) is the most prevalent non-infectious inflammatory disorder, often associated with comorbidities such as cardiovascular alterations and metabolic syndrome. These comorbidities signific...
Retraction notice to "Targeting neutrophils extracellular traps, a promising anti-thrombotic therapy for natural products from traditional Chinese herbal medicine" [Biomedicine & Pharmacotherapy 179 (2024) 117310] [0.03%]
撤稿通知:“针对天然中药产物的中草药抗血栓疗法——靶向 neutrophils 外源性陷阱[Biomedicine & Pharmacotherapy 179 (2024) 117310]]
Wei Lei,Xiao Li,Shanze Li et al.
Wei Lei et al.
Tailoring pH-responsive charge-conversional interfaces in ionizable lipid-based nanoliposomes for synchronized co-delivery and synergistic therapy of triple-negative breast cancer [0.03%]
通过调节离子化脂质基纳脂粒的pH响应电荷转换界面实现三阴性乳腺癌药物协同治疗
Yeji Choi,Ki-Hoon Choung,Minki Jin et al.
Yeji Choi et al.
Combination chemotherapy is often limited by the distinct physicochemical properties and intracellular behaviors of individual drugs. This limitation leads to poorly coordinated delivery in tumor tissues. In this study, pH-responsive ioniza...
Corrigendum to "Aerobic conditioning and ginsenoside modulation modify molecular resilience in middle-aged rats: Differential effects of individual and combined interventions" [Biomed. Pharmacother. 201 (2026) 119758] [0.03%]
“有氧锻炼和人参皂苷调节改变中年大鼠分子耐受性:单独和联合干预的差异效应”一文的勘误项 [Biomed. Pharmacother. 201 (2026) 119758]
Zahra Olfat Noubari,Jabbar Bashiri,Mohammad Mostafa Pourseif et al.
Zahra Olfat Noubari et al.