Acetonic extract of Saskatoon berry attenuates amyloid-associated neurotoxicity in cellular and Drosophila melanogaster Alzheimer's disease models [0.03%]
Saskatoon浆果醋提取物通过细胞和黑腹果蝇阿尔茨海默病模型中的淀粉样蛋白相关神经毒性作用发挥神经保护功能
Lucas Matos Martins Bernardes,Alexandre Souza Marquez,Fernanda Naves Araújo do Prado Mascarenhas et al.
Lucas Matos Martins Bernardes et al.
Saskatoon berry (Amelanchier alnifolia) is rich in polyphenols known to modulate oxidative stress and neuroinflammation, key mechanisms involved in Alzheimer's disease (AD), yet its neuroprotective potential in this context remains unexplor...
Efficacy of natural products in the treatment of melasma: A systematic review [0.03%]
天然产品治疗黄褐斑疗效的系统评价
Maria Thereza Morais,Talita Lorena Nascimento Gonçalves,Luise de Paula Soares et al.
Maria Thereza Morais et al.
Melasma is a chronic, relapsing hypermelanosis characterized by symmetric facial pigmentation and high recurrence rates. Natural products have been investigated for their antioxidant, anti-inflammatory, and depigmenting properties. This sys...
From in vitro antimicrobial activity to enhanced innate immunity in vivo: cornelian cherry (Cornus mas L.) fruit extracts correct diabetic leukocyte dysfunction through immunometabolic modulation [0.03%]
从体外抗菌活性到体内增强先天免疫：Cornus mas L.果实提取物通过免疫代谢调节纠正糖尿病白细胞功能障碍
Anna Moroz,Iryna Brodyak,Taras Peretyatko et al.
Anna Moroz et al.
The increasing prevalence of antimicrobial resistance and diabetes-associated immune dysfunction necessitates the development of novel natural agents with antimicrobial and immunomodulatory properties. Cornelian cherry fruits are rich in bi...
Engineered polymer micelles with tunable gas release for effective reduction of local fat deposits [0.03%]
具有可调气体释放功能的工程化聚合物胶束有效减少局部脂肪沉积
Choonggu Kim,Yun-Chan Lee,In Young Lee et al.
Choonggu Kim et al.
Demand is rising for non-surgical, site-specific fat reduction. This study presents fully organic biodegradable polymer micelles capable of intrinsic carbon dioxide (CO2) gas generation for adipocytolysis. Amphiphilic methoxy-poly(ethylene ...
Tuning the oxidation of boron nitride for enhancing its antitumor activity [0.03%]
通过调节氮化硼的氧化程度来增强其抗肿瘤活性
Lucas Souyris,Ingrid Charodin,Fanny Salmeron et al.
Lucas Souyris et al.
A paramount challenge in orthopedic research is the design of next-generation multifunctional biomaterials that can simultaneously promote bone regeneration and treat pathological conditions, such as bone tumors. Here, we investigated hexag...
Activity-dependent metabolic vulnerability in the APPPS1 Alzheimer's disease mouse model during isoflurane anesthesia [0.03%]
异氟醚麻醉下APPPS1阿尔茨海默病小鼠模型中活性依赖的代谢脆弱性研究
Jonas Schunack,Georg Riepe,Kathrin Textoris-Taube et al.
Jonas Schunack et al.
General anesthesia is an essential component of modern surgical and diagnostic care. Although it is overall safe in younger and healthy individuals, the situation is markedly different in patients with underlying neurological conditions lik...
Corrigendum to "Chronic sarpogrelate treatment improves renal sympathetic hyperactivity in experimental diabetes"[Biomed. Pharmacother. 176 (2024) 116814] [0.03%]
“慢性沙普格雷特治疗改善实验性糖尿病肾交感神经活性过高”[Biomed. Pharmacother. 176 (2024) 116814]的勘误表
Juan Francisco Fernández-González,José Ángel García-Pedraza,Anaïs Clara Terol-Úbeda et al.
Juan Francisco Fernández-González et al.
Iron biomarkers for prognosis, diagnosis, and therapeutic insight in colorectal cancer [0.03%]
铁生物标志物在结直肠癌预后、诊断和治疗洞察中的作用
Amani Benamor,Peter Kubatka,Dietrich Büsselberg
Amani Benamor
Background: Colorectal cancer (CRC) is a significant global health concern. It ranks as the third most common cancer, accounting for about 10% of all cancer cases, with projections estimating a substantial increase in thi...
Intravenous immunoglobulin therapy in viral infections: Lessons learned from COVID-19 [0.03%]
COVID-19病毒性感染中的静脉注射免疫球蛋白治疗：经验与教训
Meryem Alaka,Edouard Tuaillon,Benoit Desnues
Meryem Alaka
Objectives: Intravenous immunoglobulin (IVIg) exerts both antiviral and immunomodulatory effects, but its role in viral infections remains incompletely defined. This review aims to provide an integrated overview of IVIg m...
Cuminaldehyde alleviates inflammation in isoproterenol-induced acute myocardial infarction through Nrf-2/HO-1 and NF-κB signaling pathways [0.03%]
肉豆蔻醛通过Nrf-2/HO-1和NF-κB信号通路缓解异丙肾上腺素诱导的急性心肌梗死炎症反应
Shervin Prince Stanely,Jibu Thomas,Reya Issac
Shervin Prince Stanely
Myocardial infarction (MI) is a leading cause of death, and the limited efficacy of current treatments pushes the exploration of novel drug candidates.The purpose of this study was to assess the anti-inflammatory effects of cuminaldehyde, a...