Frailty first: Rethinking invasive strategies for elderly patients with non-ST-elevation myocardial infarction [0.03%]
脆弱先于老年：非ST段抬高性心肌梗死患者的侵入式治疗策略的再思考
Nikias Milaras,Konstantinos Toutouzas,Skevos Sideris
Nikias Milaras
The management of non-ST-elevation myocardial infarction (NSTEMI) in elderly patients is increasingly common, yet clinical decision-making remains challenging in the presence of frailty. In a large contemporary analysis, Popat et al examine...
Ryanodine receptor 2 mutations in catecholaminergic polymorphic ventricular tachycardia: From molecular mechanisms to precision medicine [0.03%]
肾上腺素能多形性室性心动过速中 Ryanodine 受体 2 基因突变的研究：从分子机制到精准医疗
Vaibhav Sharma
Vaibhav Sharma
Catecholaminergic polymorphic ventricular tachycardia is a classic example of the successful transfer of genetic cardiology from gene discovery to implementation of precision medicine. This inherited arrhythmia syndrome induces potentially ...
Oral anticoagulant therapy and outcomes in new-onset atrial fibrillation during acute myocardial infarction: A systematic review and meta-analysis [0.03%]
急性心肌梗死新发房颤的口服抗凝治疗及预后：系统评价和meta分析
Kristina G Pereverzeva,Ayoub Glenza,Sergey S Yakushin
Kristina G Pereverzeva
Background: New-onset atrial fibrillation (NOAF) is observed in 2%-21% of patients with acute myocardial infarction (AMI) and is associated with adverse outcomes, including increased mortality, heart failure, and stroke. ...
Phenomenon of "de Winter" pattern, sign, or syndrome: A systematic scoping review and data analysis [0.03%]
“de Winter征”现象、意义或综合征的系统综述与数据分析
Eman Elmenyar,Mohammad Adeeb Abbara,Zeina Al-Ghoul et al.
Eman Elmenyar et al.
Background: The de Winter (dW) pattern, sign, and syndrome is an ST-elevation myocardial infarction (STEMI) equivalent. The first two forms describe the electrocardiographic characteristics of this phenomenon, while dW sy...
Five-year mean follow-up of NeoHexa sirolimus eluting coronary stent: A retrospective evaluation of long-term safety and efficacy [0.03%]
NeoHexa西罗莫司洗脱冠脉支架5年平均随访：长期安全性和有效性的回顾性评估
Vijay K Trehan,Safal Safal,Siddhant Trehan et al.
Vijay K Trehan et al.
Background: Patients suffering from coronary artery disease (CAD) are experiencing significantly improved outcomes in clinical practice through the use of drug-eluting stents. However, there is still a dearth of real-worl...
Residual risk in atherosclerotic cardiovascular disease after statin therapy: Clinical mechanisms and management strategies [0.03%]
他汀治疗后动脉粥样硬化性心血管疾病剩余风险的临床机制和管理策略
Sze-Hua Tan,Jia-Lin Wu,Shu-Xiong Zhuo et al.
Sze-Hua Tan et al.
Atherosclerotic is one of the leading causes of death worldwide. Although lowering low-density lipoprotein cholesterol (LDL-C) levels reduces cardiovascular risk, studies have shown that even when LDL-C is well controlled, patients may stil...
Comparative efficacy and safety of chlorthalidone vs hydrochlorothiazide in hypertension management: A systematic review and meta-analysis [0.03%]
氯噻酮与氢氯噻嗪治疗高血压的有效性和安全性的系统评价和meta分析
Usha Kumari,Manaswini Kaka,Fakhar Abbas et al.
Usha Kumari et al.
Background: Hypertension is among the leading causes of cardiovascular diseases, including myocardial infarction (MI), stroke, and heart failure. The thiazide diuretics of chlorthalidone and hydrochlorothiazide are common...
Efficacy of nitroglycerin vs labetalol in hypertensive emergency among patients with a history of coronary artery disease [0.03%]
冠心病史患者的高血压急症患者使用硝酸甘油与拉贝洛尔的效果比较
Ahmed Jamal Chaudhary,Wasim Akbar Bhat,Affan Ul Haq et al.
Ahmed Jamal Chaudhary et al.
Background: Hypertensive emergencies, characterized by severe blood pressure elevation (> 180/120 mmHg) with end-organ damage, pose significant risks in patients with coronary artery disease (CAD), where rapid yet safe re...
Frailty in elderly patients with non-ST elevation myocardial infarction: Balancing the risks and benefits of percutaneous coronary intervention [0.03%]
老年非ST段抬高型心肌梗死患者的心血管介入治疗风险与获益的评估——兼论衰弱状态的作用
Hussam Ali,Flavio Airoldi,Riccardo Cappato
Hussam Ali
Frailty has emerged as a critical determinant of clinical outcomes in cardiovascular patients undergoing invasive management. Although percutaneous coronary intervention (PCI) remains the cornerstone of therapy for acute coronary syndromes,...
Mothers against decapentaplegic homolog 4 as a proteomic hub in vascular remodeling and residual cardiovascular risk [0.03%]
SMAD4在血管重塑和心血管残余风险中的中心作用：一项蛋白质组学研究
Davide Ramoni,Federico Carbone,Luca Liberale et al.
Davide Ramoni et al.
Translational cardiovascular medicine increasingly relies on systems-level approaches to uncover therapeutic targets that bridge molecular mechanisms and clinical outcomes. Recent proteomic analyses in experimental myocardial infarction mod...